Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Nina M Goodey"'
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 4, p e0011303 (2023)
Lymphatic filariasis is a debilitating illness with an estimated 50 million cases as of 2018. The majority of cases are caused by the parasitic worm W. bancrofti and additional cases by the worms B. malayi and B. timori. Dihydrofolate reductase (DHFR
Externí odkaz:
https://doaj.org/article/8c20d36c91bc4e7eb05fa27a07735415
Autor:
Andrew M Tobias, Dea Toska, Keith Lange, Tyler Eck, Rohit Bhat, Cheryl A Janson, David P Rotella, Ueli Gubler, Nina M Goodey
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197173 (2018)
Filariasis is a tropical disease caused by the parasitic nematodes Wuchereria bancrofti and Brugia malayi. Known inhibitors of dihydrofolate reductase (DHFR) have been previously shown to kill Brugia malayi nematodes and to inhibit Brugia malayi DHFR
Externí odkaz:
https://doaj.org/article/2c8a0df7e2ef4f8b811d5074508981ba
Autor:
Bhagyashree P. Vaidya, Diane F. Hagmann, Jamila Haramuniz, Jennifer Adams Krumins, Nina M. Goodey
Publikováno v:
Environmental pollution (Barking, Essex : 1987). 312
Restoring enzyme function in barren, brownfield soils using green strategies can improve microbial functioning and enable phytoremediation. It is known that adding simple, readily metabolized substrates secreted by growing plant roots (root exudates)
Autor:
Nina M. Goodey, Sarah Cho, Bhatti Maryum, Huma Booter, Cintya Moran, Natalie Jefferson, Savannah Van Den Berg, Patryjca Marin, Ashley Peralta, Katherine Margolin, David Konas
Publikováno v:
The FASEB Journal. 36
Autor:
Frank Gallagher, Nina M. Goodey, Diane Hagmann, Jay Prakash Singh, Claus Holzapfel, Megan Litwhiler, Jennifer Adams Krumins
Publikováno v:
Diversity, Vol 10, Iss 4, p 119 (2018)
The biodiversity of urban and post-industrial ecosystems is a highly relevant and growing new frontier in ecological research. Even so, the functionality of these ecosystems may not always be successfully predicted based on prior biodiversity and eco
Externí odkaz:
https://doaj.org/article/ac5dcb5844b04905abb8ec3095ddfffe
Autor:
Taylor Wieczerak, Daniel Rynerson, Archana Prasad, Bernabas Wolde, Pankaj Lal, Ashwani Vasishth, Nina M. Goodey, Amy R. Tuininga
Publikováno v:
SN Social Sciences. 2
Autor:
Tyler Eck, Mariana Laureano de Souza, Melvin Delvillar, Kutub Ashraf, Rammohan R. Yadav Bheemanaboina, Ramappa Chakrasali, Tamara Kreiss, John J. Siekierka, David P. Rotella, Purnima Bhanot, Nina M. Goodey
Publikováno v:
Chembiochem
P. falciparum cGMP-dependent protein kinase (PfPKG) is an enticing anti-malarial drug target. Novel chemotypes are needed because existing inhibitors have safety issues that may prevent further development. This work demonstrates isoxazole-based comp
Publikováno v:
ChemBioChem. 23
Publikováno v:
ChemBioChem. 23
Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis, affects millions of people worldwide. Several TB drugs have lost efficacy due to emerging drug resistance and new anti-TB targets are needed. Recent research suggests that indole-3
Autor:
Nina M. Goodey, Bheemanoboina Rry, Tyler Eck, John J. Siekierka, Ramappa Chakrasali, Purnima Bhanot, Laureano de Souza M, Tamara Kreiss, David P. Rotella
P. falciparum cGMP-dependent protein kinase (PfPKG) is an enticing anti-malarial drug target. Structurally novel isoxazole-based compounds were shown to be ATP competitive inhibitors of PfPKG. Isoxazoles 3 and 5 had Ki values of 0.7 ± 0.2 and 2.3 ±
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::354171d010b685e50cfad3da790134e4
https://doi.org/10.1101/2021.06.24.449800
https://doi.org/10.1101/2021.06.24.449800