Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nina M Berkowitz"'
Autor:
Joseph P. Casazza, Amelia R. Hofstetter, Pamela J. M. Costner, LaSonji A. Holman, Cynthia S. Hendel, Alicia T. Widge, Richard L. Wu, William R. Whalen, Jennifer Cunningham, Anita Arthur, Xiaolin Wang, Abidemi Ola, Jamie Saunders, Floreliz Mendoza, Laura Novik, Maria C. Burgos Florez, Ana M. Ortega-Villa, Preeti J. Apte, Larisa Strom, Lu Wang, Marjaan Imam, Manjula Basappa, Mursal Naisan, Mike Castro, Jessica F. Trost, Sandeep R. Narpala, Hillary A. Vanderven, Galina V. Yamshchikov, Nina M. Berkowitz, Ingelise J. Gordon, Sarah H. Plummer, Diane L. Wycuff, Sandra Vazquez, Rebecca A. Gillespie, Adrian Creanga, William C. Adams, Kevin Carlton, Jason G. Gall, Adrian B. McDermott, Leonid A. Serebryannyy, Katherine V. Houser, Richard A. Koup, Barney S. Graham, Julie E. Ledgerwood, John R. Mascola, Theodore C. Pierson, Sarah F. Andrews, Masaru Kanekiyo, Lesia K. Dropulic, The VRC 323 study team
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract The relative conservation of the influenza hemagglutinin (HA) stem compared to that of the immunodominant HA head makes the HA stem an attractive target for broadly protective influenza vaccines. Here we report the first-in-human, dose-escal
Externí odkaz:
https://doaj.org/article/96bea20f4a6e46d8a78a3f7c6943f262
Autor:
Katherine V. Houser, Martin R. Gaudinski, Myra Happe, Sandeep Narpala, Raffaello Verardi, Edward K. Sarfo, Angela R. Corrigan, Richard Wu, Ro Shauna Rothwell, Laura Novik, Cynthia S. Hendel, Ingelise J. Gordon, Nina M. Berkowitz, Cora Trelles Cartagena, Alicia T. Widge, Emily E. Coates, Larisa Strom, Somia Hickman, Michelle Conan-Cibotti, Sandra Vazquez, Olga Trofymenko, Sarah Plummer, Judy Stein, Christopher L. Case, Martha Nason, Andrea Biju, Danealle K. Parchment, Anita Changela, Cheng Cheng, Hongying Duan, Hui Geng, I-Ting Teng, Tongqing Zhou, Sarah O'Connell, Chris Barry, Kevin Carlton, Jason G. Gall, Britta Flach, Nicole A. Doria-Rose, Barney S. Graham, Richard A. Koup, Adrian B. McDermott, John R. Mascola, Peter D. Kwong, Julie E. Ledgerwood
Publikováno v:
EClinicalMedicine, Vol 48, Iss , Pp 101477- (2022)
Background: Advances in therapeutic drugs have increased life-expectancies for HIV-infected individuals, but the need for an effective vaccine remains. We assessed safety and immunogenicity of HIV-1 vaccine, Trimer 4571 (BG505 DS-SOSIP.664) adjuvante
Externí odkaz:
https://doaj.org/article/49b7b8d527474cb4acebedb3025b53dc
Autor:
Kirsten E Lyke, Andrea A Berry, Kaitlin Mason, Azza H Idris, Mark O'Callahan, Myra Happe, Larisa Strom, Nina M Berkowitz, Mercy Guech, Zonghui Hu, Mike Castro, Manjula Basappa, Lu Wang, Kwang Low, LaSonji A Holman, Floreliz Mendoza, Ingelise J Gordon, Sarah H Plummer, Olga Trofymenko, Kathleen S Strauss, Sudhaunshu Joshi, Biraj Shrestha, Matthew Adams, Andrezza Campos Chagas, Jittawadee R Murphy, Judy Stein, Somia Hickman, Andrew McDougal, Bob Lin, Sandeep R Narpala, Sandra Vazquez, Leonid Serebryannyy, Adrian McDermott, Martin R Gaudinski, Edmund V Capparelli, Emily E Coates, Richard L Wu, Julie E Ledgerwood, Lesia K Dropulic, Robert A Seder, Cheryl Young, Colleen Boyce, Jennifer Winkler, Susan Holian, Nancy Greenberg, Shirley George, Alyson Kwon, Brenda Dorsey, Ana Raquel Da Costa, William Witt, Daryl Grays, Arren Gapasin, Paula Bernal, Jeffrey Floyd, Eric Goldstein, Leslie Howe, Myounghee Lee, Jennifer Marron, Kelly Brooks, Lisa Turek, Patricia Farley, Shantel Frels, Delores Booth, Jason Gall, Kevin Carlton, Gabriela Albright, Nadia Amharref, Kandace Atallah, Sashikanth Banappagari, Niutish Bastani, Daniel Blackstock, Bobby Boonyaratanakornkit, Elizabeth Carey, Adam Charlton, Rajoshi Chaudhuri, Alegria M. Caringal, Mingzhong Chen, Peifeng Chen, Wei Cheng, Daniel Gowetski, Krishana Gulla, Erica Hastings, Joe Horwitz, Vera Ivleva, Dan Kordella, Lisa A. Kueltzo, Sara Lagler, Matt Le, James Lee, Paula Lei, Yile Li, Attila Nagy, Aakash Patel, Peyi Runsewe, Will Shadrick, Shamitha Shetty, Hairong Wang, Calvin Webber, Farah Vejzagic, Yoo-Jung Yang
Publikováno v:
The Lancet Infectious Diseases. 23:578-588
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f600caf7a91af2dc3f76ba29b4af090
https://doi.org/10.1016/s1473-3099(22)00793-9
https://doi.org/10.1016/s1473-3099(22)00793-9
Autor:
Richard L, Wu, Azza H, Idris, Nina M, Berkowitz, Myra, Happe, Martin R, Gaudinski, Christian, Buettner, Larisa, Strom, Seemal F, Awan, LaSonji A, Holman, Floreliz, Mendoza, Ingelise J, Gordon, Zonghui, Hu, Andrezza, Campos Chagas, Lawrence T, Wang, Lais, Da Silva Pereira, Joseph R, Francica, Neville K, Kisalu, Barbara J, Flynn, Wei, Shi, Wing-Pui, Kong, Sarah, O'Connell, Sarah H, Plummer, Allison, Beck, Adrian, McDermott, Sandeep R, Narpala, Leonid, Serebryannyy, Mike, Castro, Rosa, Silva, Marjaan, Imam, Iris, Pittman, Somia P, Hickman, Andrew J, McDougal, Ashly E, Lukoskie, Jittawadee R, Murphy, Jason G, Gall, Kevin, Carlton, Patricia, Morgan, Ellie, Seo, Judy A, Stein, Sandra, Vazquez, Shinyi, Telscher, Edmund V, Capparelli, Emily E, Coates, John R, Mascola, Julie E, Ledgerwood, Lesia K, Dropulic, Robert A, Seder, Benjamin, Clarkson
Publikováno v:
The New England journal of medicine. 387(5)
New approaches for the prevention and elimination of malaria, a leading cause of illness and death among infants and young children globally, are needed.We conducted a phase 1 clinical trial to assess the safety and pharmacokinetics of L9LS, a next-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fefa9632a0575a3719d566aba7ba3df
https://pubmed.ncbi.nlm.nih.gov/36260982
https://pubmed.ncbi.nlm.nih.gov/36260982
Autor:
Peifeng Chen, Anita Arthur, Kaitlyn M. Morabito, Kristin Leach, Xiaolin Wang, Grace L. Chen, Attila Nagy, Lauren A. Chang, Jon Cooper, Amy L. Chamberlain, Janel Holland-Linn, Olga Vasilenko, Alicia T. Widge, Shufeng Bai, Judith A Stein, LaSonji A. Holman, Cristina Carter, Iris Pittman, Deepika Gollapudi, Lisa A. Kueltzo, Colleen Fridley, Michelle C. Crank, Amritha Menon, William Whalen, Mridul Ghosh, Cynthia S. Hendel, Martha Nason, Amy Liu, Althaf Hussain, Laura Novik, Pernell Williams, Maria Burgos Florez, Robert T. Bailer, Thuy Nguyen, Brenda Larkin, Tracy J. Ruckwardt, Pamela Costner, Lam Le, Zhong Zhao, Elizabeth Carey, Vera Ivleva, Jennifer Walters, John R. Mascola, Jennifer Cunningham, Olga Trofymenko, Ya-chen Chang, Somia P. Hickman, Martin R. Gaudinski, Richard M. Schwartz, Slobodanka D. Manceva, Kevin Carlton, Barney S. Graham, Rahul Ragunathan, Jason G. D. Gall, Ana M. Ortega-Villa, Colin Tran, Sarah H. Plummer, Abidemi Ola, Ro Shauna S Rothwell, Ingelise J. Gordon, Mingzhong Chen, Jamie G. Saunders, Aba Mensima Eshun, Bob C. Lin, Azad Kumar, Nina M. Berkowitz, Xun Liu, Cora Trelles Cartagena, Emily Phung, Galina Yamshchikov, Joe Horwitz, Sarah O’Connell, Florence Kaltovich, Floreliz Mendoza, LaShawn Requilman, Man Chen, Preeti Apte, Christopher Lee, Renunda Hicks
Publikováno v:
Lancet Respir Med
Multiple active vaccination approaches have proven ineffective in reducing the substantial morbidity and mortality caused by respiratory syncytial virus (RSV) in infants and older adults (aged ≥65 years). A vaccine conferring a substantial and sust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ae60b574c97c5be6e3eabd0b1e70f3
https://doi.org/10.1016/s2213-2600(21)00098-9
https://doi.org/10.1016/s2213-2600(21)00098-9
Autor:
Kirsten E. Lyke, Andrea A. Berry, Kaitlin Mason, Azza A. Idris, Mark O'Callahan, Myra Happe, Larisa Strom, Nina M. Berkowitz, Mercy Guech, Zonghui Hu, Mike Castro, Manjula Basappa, Lu Wang, Muhammed Naqvi, Kwang Low, LaSonji A. Holman, Floreliz Mendoza, Ingelize J. Gordon, Sarah H. Plummer, Olga Trofymenko, Kathleen S. Strauss, Sudhaunshu Joshi, Biraj Shrestha, Matthew Adams, Andrezza Campos Chagas, Jittawadee R. Murphy, Judy A. Stein, Somia P. Hickman, Andrew J. McDougal, Bob Lin, Sandeep Narparla, Sandra Vazquez, Leonid Serebryannyy, Adrian McDermott, Martin R. Gaudinski, Edmund V. Capparelli, Emily E. Coates, Richard L. Wu, Julie E. Ledgerwood, Lesia K. Dropulic, Robert A. Seder
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1851ee757a5ef9dde4de1c6324b99f89
https://doi.org/10.2139/ssrn.4240619
https://doi.org/10.2139/ssrn.4240619
Autor:
Martin R, Gaudinski, Nina M, Berkowitz, Azza H, Idris, Emily E, Coates, LaSonji A, Holman, Floreliz, Mendoza, Ingelise J, Gordon, Sarah H, Plummer, Olga, Trofymenko, Zonghui, Hu, Andrezza, Campos Chagas, Sarah, O'Connell, Manjula, Basappa, Naomi, Douek, Sandeep R, Narpala, Christopher R, Barry, Alicia T, Widge, Renunda, Hicks, Seemal F, Awan, Richard L, Wu, Somia, Hickman, Diane, Wycuff, Judy A, Stein, Christopher, Case, Brian P, Evans, Kevin, Carlton, Jason G, Gall, Sandra, Vazquez, Britta, Flach, Grace L, Chen, Joseph R, Francica, Barbara J, Flynn, Neville K, Kisalu, Edmund V, Capparelli, Adrian, McDermott, John R, Mascola, Julie E, Ledgerwood, Robert A, Seder
Publikováno v:
The New England journal of medicine. 385(9)
Additional interventions are needed to reduce the morbidity and mortality caused by malaria.We conducted a two-part, phase 1 clinical trial to assess the safety and pharmacokinetics of CIS43LS, an antimalarial monoclonal antibody with an extended hal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58451404ce1ce4b7789d3fcaca3de9f4
https://pubmed.ncbi.nlm.nih.gov/35590195
https://pubmed.ncbi.nlm.nih.gov/35590195
Autor:
Amarendra, Pegu, Sarah E, O'Connell, Stephen D, Schmidt, Sijy, O'Dell, Chloe A, Talana, Lilin, Lai, Jim, Albert, Evan, Anderson, Hamilton, Bennett, Kizzmekia S, Corbett, Britta, Flach, Lisa, Jackson, Brett, Leav, Julie E, Ledgerwood, Catherine J, Luke, Mat, Makowski, Martha C, Nason, Paul C, Roberts, Mario, Roederer, Paulina A, Rebolledo, Christina A, Rostad, Nadine G, Rouphael, Wei, Shi, Lingshu, Wang, Alicia T, Widge, Eun Sung, Yang, John H, Beigel, Barney S, Graham, John R, Mascola, Mehul S, Suthar, Adrian B, McDermott, Nicole A, Doria-Rose, Jae, Arega, Wendy, Buchanan, Mohammed, Elsafy, Binh, Hoang, Rebecca, Lampley, Aparna, Kolhekar, Hyung, Koo, Catherine, Luke, Mamodikoe, Makhene, Seema, Nayak, Rhonda, Pikaart-Tautges, Janie, Russell, Elisa, Sindall, Pratap, Kunwar, Evan J, Anderson, Amer, Bechnak, Mary, Bower, Andres F, Camacho-Gonzalez, Matthew, Collins, Ana, Drobeniuc, Venkata Viswanadh, Edara, Srilatha, Edupuganti, Katharine, Floyd, Theda, Gibson, Cassie M Grimsley, Ackerley, Brandi, Johnson, Satoshi, Kamidani, Carol, Kao, Colleen, Kelley, Hollie, Macenczak, Michele Paine, McCullough, Etza, Peters, Varun K, Phadke, Nadine, Rouphael, Erin, Scherer, Amy, Sherman, Kathy, Stephens, Mehgan, Teherani, Jessica, Traenkner, Juton, Winston, Inci, Yildirim, Lee, Barr, Joyce, Benoit, Barbara, Carste, Joe, Choe, Maya, Dunstan, Roxanne, Erolin, Jana, Ffitch, Colin, Fields, Lisa A, Jackson, Erika, Kiniry, Susan, Lasicka, Stella, Lee, Matthew, Nguyen, Stephanie, Pimienta, Janice, Suyehira, Michael, Witte, Nedim Emil, Altaras, Andrea, Carfi, Marjorie, Hurley, Rolando, Pajon, Wellington, Sun, Tal, Zaks, Rhea N, Coler, Sasha E, Larsen, Kathleen M, Neuzil, Lisa C, Lindesmith, David R, Martinez, Jennifer, Munt, Michael, Mallory, Caitlin, Edwards, Ralph S, Baric, Nina M, Berkowitz, Eli A, Boritz, Kevin, Carlton, Pamela, Costner, Adrian, Creanga, Daniel C, Douek, Martin, Gaudinski, Ingelise, Gordon, LaSonji, Holman, Kwanyee, Leung, Bob C, Lin, Mark K, Louder, Kaitlyn M, Morabito, Laura, Novik, Sarah, O'Connell, Marcelino, Padilla, Phillip A, Swanson, Yi, Zhang, James D, Chappell, Mark R, Denison, Tia, Hughes, Xiaotao, Lu, Andrea J, Pruijssers, Laura J, Stevens, Christine M, Posavad, Michael, Gale, Vineet, Menachery, Pei-Yong, Shi
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
SARS-CoV-2 mutations may diminish vaccine-induced protective immune responses, and the durability of such responses has not been previously reported. Here, we present a comprehensive assessment of the impact of variants B.1.1.7, B.1.351, P.1, B.1.429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e783dd6f4280d48257f617acf459420
https://pubmed.ncbi.nlm.nih.gov/34385356
https://pubmed.ncbi.nlm.nih.gov/34385356
Autor:
Katherine V, Houser, Grace L, Chen, Cristina, Carter, Michelle C, Crank, Thuy A, Nguyen, Maria Claudia, Burgos Florez, Nina M, Berkowitz, Floreliz, Mendoza, Cynthia Starr, Hendel, Ingelise J, Gordon, Emily E, Coates, Sandra, Vazquez, Judy, Stein, Christopher L, Case, Heather, Lawlor, Kevin, Carlton, Martin R, Gaudinski, Larisa, Strom, Amelia R, Hofstetter, C Jason, Liang, Sandeep, Narpala, Christian, Hatcher, Rebecca A, Gillespie, Adrian, Creanga, Masaru, Kanekiyo, Julie E, Raab, Sarah F, Andrews, Yi, Zhang, Eun Sung, Yang, Lingshu, Wang, Kwanyee, Leung, Wing-Pui, Kong, Alec W, Freyn, Raffael, Nachbagauer, Peter, Palese, Robert T, Bailer, Adrian B, McDermott, Richard A, Koup, Jason G, Gall, Frank, Arnold, John R, Mascola, Barney S, Graham, Julie E, Ledgerwood, Colin, Tran
Publikováno v:
Nature medicine. 28(2)
Currently, licensed seasonal influenza vaccines display variable vaccine effectiveness, and there remains a need for novel vaccine platforms capable of inducing broader responses against viral protein domains conserved among influenza subtypes. We co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c69a375fcdfc5aedf8c893234b7db8b8
https://pubmed.ncbi.nlm.nih.gov/35115706
https://pubmed.ncbi.nlm.nih.gov/35115706
Autor:
Scott A. Rush, Pamela Costner, John R. Mascola, Morgan S.A. Gilman, Yi Zhang, Samuel Darko, Barney S. Graham, Chaim A. Schramm, Alexandrine Derrien-Colemyn, John Misasi, Guillaume Stewart-Jones, Bharat Madan, Peter D. Kwong, Martin R. Gaudinski, Chen-Hsiang Shen, Grace L. Chen, Kaitlyn M. Morabito, Amy Ransier, Jason S. McLellan, Michelle C. Crank, Larissa Ault, Tracy J. Ruckwardt, LaSonji A. Holman, Daniel C. Douek, Sarah A.M. Lucas, Emily Phung, Nina M. Berkowitz, Brandon J. DeKosky, Nicole A. Doria-Rose, Nancy J. Sullivan, Daniel Wrapp, Maryam Mukhamedova, Lingshu Wang, Lauren A. Chang, Somia P. Hickman
Publikováno v:
SSRN Electronic Journal.
An effective vaccine for RSV is an unrealized public health goal. Recently, a single dose of the prefusion-stabilized fusion (F) glycoprotein subunit vaccine (DS-Cav1) was shown to substantially increase serum neutralizing activity in healthy adults.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a753eb36429a1136c8b6be4ec661c83
https://doi.org/10.2139/ssrn.3712702
https://doi.org/10.2139/ssrn.3712702