Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Nina Ly"'
Autor:
Katherine Labbé, Lauren LeBon, Bryan King, Ngoc Vu, Emily H. Stoops, Nina Ly, Austin E. Y. T. Lefebvre, Phillip Seitzer, Swathi Krishnan, Jin-Mi Heo, Bryson Bennett, Carmela Sidrauski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The integrated stress response (ISR) enables cells to cope with a variety of insults, but its specific contribution to downstream cellular outputs remains unclear. Using a synthetic tool, we selectively activate the ISR without co-activation
Externí odkaz:
https://doaj.org/article/27e86f13e45248efb23da08ad179a50a
Autor:
Simina Grigoriu, Rachel Bond, Pilar Cossio, Jennifer A Chen, Nina Ly, Gerhard Hummer, Rebecca Page, Martha S Cyert, Wolfgang Peti
Publikováno v:
PLoS Biology, Vol 11, Iss 2, p e1001492 (2013)
Ser/thr phosphatases dephosphorylate their targets with high specificity, yet the structural and sequence determinants of phosphosite recognition are poorly understood. Calcineurin (CN) is a conserved Ca(2+)/calmodulin-dependent ser/thr phosphatase a
Externí odkaz:
https://doaj.org/article/869148b1dc734871b219ca7c467c926b
Autor:
James J. Lee, Nina Ly, Rejani B. Kunjamma, Holly M. Robb, Eric G. Mohler, Janani Sridar, Qi Hao, José Zavala-Solorio, Chunlian Zhang, Ganesh Kolumam, Nick van Bruggen, Caitlin F. Connelly, Carmela Sidrauski
eIF2B is a decameric guanine nucleotide exchange factor (GEF) that is essential for protein synthesis and a key effector of the integrated stress response (ISR). Hypomorphic mutations in any of the eIF2B subunits are associated with Vanishing White M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a2d80061127e97b50c933f8fc1faa9d
https://doi.org/10.1101/2023.05.06.539602
https://doi.org/10.1101/2023.05.06.539602
Autor:
Nina Lykke
Publikováno v:
Kvinder, Køn & Forskning, Vol 37, Iss 1 (2024)
This article focuses on green politics in Denmark, highlighting how mainstream political rhetorics with cruel optimism promote the country as a green world leader, while turning a blind eye to the eco-cides that have formed its landscapes. The primar
Externí odkaz:
https://doaj.org/article/9fe527f2af6e4eb1ad728de835ef8a42
Autor:
Nina Lykkegaard Gehr, Páll Karlsson, Signe Timm, Signe Christensen, Christian Andreas Hvid, Jana Peric, Torben Frøstrup Hansen, Lotte Lauritzen, Nanna Brix Finnerup, Lise Ventzel
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Oxaliplatin-induced peripheral neuropathy (OIPN) in general and painful OIPN in particular is a debilitating late effect that severely affects cancer survivors’ quality of life and causes premature cessation of potentially lifes
Externí odkaz:
https://doaj.org/article/207e261681104d0d8d0a91e3e2e700b1
Publikováno v:
PAIN Reports, Vol 9, Iss 2, p e1138 (2024)
Abstract. Neuropathic pain is a challenging chronic pain condition. Limited knowledge exists regarding the relative effectiveness of pharmacological treatments, and differences in trial design and impact of the placebo response preclude indirect comp
Externí odkaz:
https://doaj.org/article/291c8e78c97b44bcbe53e5ae64ba892a
Publikováno v:
Journal of Biological Chemistry. 292:16709-16721
Calcineurin, the conserved Ca2+/calmodulin-regulated phosphatase and target of immunosuppressants, plays important roles in the circulatory, nervous, and immune systems. Calcineurin activity strictly depends on Ca2+ and Ca2+-bound calmodulin (Ca2+/Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc61f4e1c0f26017fa62b6a5b01d6270
https://doi.org/10.1074/jbc.m117.795146
https://doi.org/10.1074/jbc.m117.795146
Autor:
Martha S. Cyert, Nina Ly
Publikováno v:
Molecular Biology of the Cell. 28:576-586
Calcineurin, the conserved Ca2+/calmodulin-activated phosphatase, is required for viability during prolonged exposure to pheromone and acts through multiple substrates to down-regulate yeast pheromone signaling. Calcineurin regulates Dig2 and Rod1/Ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6bef5d07ab6203a22e789f879776dc1
https://doi.org/10.1091/mbc.e16-06-0432
https://doi.org/10.1091/mbc.e16-06-0432
Publikováno v:
The Journal of biological chemistry. 292(40)
Calcineurin, the conserved Ca2+/calmodulin-regulated phosphatase and target of immunosuppressants, plays important roles in the circulatory, nervous, and immune systems. Calcineurin activity strictly depends on Ca2+ and Ca2+-bound calmodulin (Ca2+/Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d41bd9eaae8b5b55ff6acd5c1c845e8
https://pubmed.ncbi.nlm.nih.gov/28842480
https://pubmed.ncbi.nlm.nih.gov/28842480
Publikováno v:
Horizontes Antropológicos, Vol 29, Iss 66 (2023)
Resumo A biodiversidade assegura a existência da vida humana no planeta. Os países signatários das convenções globais precisam formular estratégias para alcançar as metas definidas e essas estratégias são estabelecidas por meio de políticas
Externí odkaz:
https://doaj.org/article/bf2d2dd589834ee8b34199e727cb194a