Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nina Lukinova"'
Autor:
Roberto Salgado, David B. Solit, David L. Rimm, Jan Bogaerts, Renzo Canetta, Tracy Lively, Kim Lyerly, Paul N. Span, Alison Bateman-House, Amr Makady, L. Bergmann, Sumimasa Nagai, Chris Smith, Mark Robson, Mary Savage, Emile Voest, Christopher Sweeney, Philippe Lambin, Marlene Thomas, Lyndsay Harris, Denis Lacombe, Chistophe Massard, Rene Bernards, Richard Sullivan, Sabine Tejpar, Nina Lukinova, Herbert K. Lyerly, Helen Moore, Malcolm A. Smith, Laura Yee, Ray DuBois, William C. Hahn, Pasi Janne, Cheryl L. Willman, David Rimm, Lothar Bergmann, Ian A. Cree, Priti Hegde, Shirley Hopper, Marc Robson, Magnus Ingelman-Sundberg, Gwen Nichols, Francois Maignen, Benjamin Besse, Rafal Swierzewski, Astrid Kiermaier, Christophe Massard, Michael Caliguri, Victor Velculescu, Paolo Foggi, Willem C. Hahn, Vassilis Golfinopoulos
Publikováno v:
European Journal of Cancer, 114, pp. 128-136
European Journal of Cancer, 114, 128-136
European Journal of Cancer, 114, 128-136. ELSEVIER SCI LTD
European Journal of Cancer, 114, 128-136
European Journal of Cancer, 114, 128-136. ELSEVIER SCI LTD
Academic, industry, regulatory leaders and patient advocates in cancer clinical research met in November 2018 at the Innovation and Biomarkers in Cancer Drug Development meeting in Brussels to address the existing dichotomy between increasing calls f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065a865995916dc6e9a0afd348575ec7
https://doi.org/10.1016/j.ejca.2019.03.025
https://doi.org/10.1016/j.ejca.2019.03.025
Autor:
Shelly Bambina, Nina Lukinova, Joshua J. Gruber, Leah R. Sabin, Rui Zhou, Sara Cherry, Allison Berman, Chi Kong Lau, Craig B. Thompson
Publikováno v:
Cell. 138:340-351
Intrinsic immune responses autonomously inhibit viral replication and spread. One pathway that restricts viral infection in plants and insects is RNA interference (RNAi), which targets and degrades viral RNA to limit infection. To identify additional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4633337355bb6168aa4775fa88348d
https://doi.org/10.1016/j.cell.2009.04.045
https://doi.org/10.1016/j.cell.2009.04.045
Publikováno v:
Immunity. 30:588-598
SummaryIntrinsic innate immune mechanisms are the first line of defense against pathogens and exist to control infection autonomously in infected cells. Here, we showed that autophagy, an intrinsic mechanism that can degrade cytoplasmic components, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc9b634a5636ede880f3f16203172e7
https://doi.org/10.1016/j.immuni.2009.02.009
https://doi.org/10.1016/j.immuni.2009.02.009
Publikováno v:
Genetics. 153:1789-1797
We performed a systematic lethal mutagenesis of the genomic region uncovered by Df(3L)rdgC-co2 (cytological interval 77A–D) to isolate mutations in the single known Presenilin (Psn) gene of Drosophila melanogaster. Because this segment of chromosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e037bb61f99ecc12db753c859c3d56fa
https://doi.org/10.1093/genetics/153.4.1789
https://doi.org/10.1093/genetics/153.4.1789
Publikováno v:
Nature. 398:525-529
Presenilin proteins have been implicated both in developmental signalling by the cell-surface protein Notch and in the pathogenesis of Alzheimer's disease. Loss of presenilin function leads to Notch/lin-12-like mutant phenotypes in Caenorhabditis ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5df72a643dd5ba66c0f0d68445932555
https://doi.org/10.1038/19096
https://doi.org/10.1038/19096
Autor:
Defne A. Amado, Nina Lukinova, Allan A. Hunter, Joshua L. Dunaief, Tzvete Dentchev, Natalie Wolkow, Gui-Shuang Ying, Janet R. Sparrow, Jared Iacovelli
Iron is essential for life because of its role in one-electron redox chemistry in the electron transport chain and as a cofactor in heme and iron-sulfur cluster–containing proteins. However, it also represents a potentially dangerous electron-trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6c6fb98e9433c118f5b1aa849a8671
https://europepmc.org/articles/PMC2665187/
https://europepmc.org/articles/PMC2665187/
Publikováno v:
Investigative ophthalmologyvisual science. 47(7)
PURPOSE. Menkes and Wilson diseases are associated with retinal degeneration. The Menkes and Wilson genes are homologous copper transporters, but differences in their expression pattern lead to different disease manifestations. To determine whether t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e013c44f9fe7e03d61b51e5805ee7caa
https://pubmed.ncbi.nlm.nih.gov/16799059
https://pubmed.ncbi.nlm.nih.gov/16799059
Publikováno v:
Blood. 122:4816-4816
Introduction A highly specific, rapid, robust and sensitive assay for Factor Xa (FXa) activity will greatly improve monitoring and optimization of anticoagulant therapy by direct FXa inhibitors and by low molecular weight (LMW) heparins. We have deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63a775dc95de33abb4d05c0912ed0dd8
https://doi.org/10.1182/blood.v122.21.4816.4816
https://doi.org/10.1182/blood.v122.21.4816.4816
Autor:
Chen Zhao, Joshua L. Dunaief, Noriko Esumi, Kandace Gollomp, Ayala King, Natalie Wolkow, Nina Lukinova, Douglas Vollrath, Leonard Feiner, Jared Iacovelli, Peter Veldman, Donald J. Zack, Pallavi Ojha, Eric A. Pierce
Publikováno v:
Investigative Opthalmology & Visual Science. 52:1378
The cre-loxP system has revolutionized mouse genetics by facilitating the creation of cell-type–specific knockout animal models. Cre recombinase is a P1 bacteriophage protein that binds to a 34-bp-long target recognition site known as loxP.1 Throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3b3649407609b6ae1cb292666da6d0
https://doi.org/10.1167/iovs.10-6347
https://doi.org/10.1167/iovs.10-6347
Publikováno v:
Neurobiology of Aging. 21:25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::234a67f24a89b528d6e1a44197806862
https://doi.org/10.1016/s0197-4580(00)82790-6
https://doi.org/10.1016/s0197-4580(00)82790-6