Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nina Langoth"'
Autor:
Andrea Pathe-Neuschäfer-Rube, Frank Neuschäfer-Rube, Gerald Haas, Nina Langoth-Fehringer, Gerhard Paul Püschel
Publikováno v:
Toxins, Vol 10, Iss 9, p 360 (2018)
Despite the implementation of cell-based replacement methods, the mouse lethality assay is still frequently used to determine the activity of botulinum toxin (BoNT) for medical use. One explanation is that due to the use of neoepitope-specific antibo
Externí odkaz:
https://doaj.org/article/4bdf46d45e1540faa25759d2d5226b5f
Publikováno v:
Pharmaceutical Research. 22:2045-2050
Buccal administration of pituitary adenylate cyclase-activating polypeptide (PACAP) could represent a new possibility for the treatment of type 2 diabetes. In this study the effect of various buccal permeation enhancers on PACAP and FD-4 was evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e09cb7f0550c5c8e6283c35016014b
https://doi.org/10.1007/s11095-005-7894-4
https://doi.org/10.1007/s11095-005-7894-4
Publikováno v:
International Journal of Pharmaceutics. 278:353-360
d -Glucosamine and chitosan were modified by the immobilization of thiol groups utilizing 2-iminothiolane. The toxicity profile of the resulting d -glucosamine-TBA (4-thiobutylamidine) conjugate, of chitosan-TBA conjugate and of the corresponding unm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722a547465b6e32f5f9ea4c5266ba43e
https://doi.org/10.1016/j.ijpharm.2004.03.016
https://doi.org/10.1016/j.ijpharm.2004.03.016
Publikováno v:
International Journal of Pharmaceutics. 252:141-148
The purpose of the present study was to investigate the benefit of thiolated polymers (thiomers) for the development of buccal drug delivery systems. L-Cysteine was thereby covalently attached to polycarbophil (PCP) mediated by a carbodiimide. The re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82965a57a655a46396710cb545c63ba
https://doi.org/10.1016/s0378-5173(02)00638-5
https://doi.org/10.1016/s0378-5173(02)00638-5
Publikováno v:
Pharmaceutical Research. 20:931-936
Purpose. It was the purpose of this study to develop a new oral drug delivery system for low molecular weight heparin (LMWH) providing an improved bioavailability and a prolonged therapeutic effect.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb4db71691439793683510d19a5f2a20
https://doi.org/10.1023/a:1023803706746
https://doi.org/10.1023/a:1023803706746
Publikováno v:
International Journal of Pharmaceutics. 233:141-147
Peptide drugs in buccal bioadhesive delivery systems are exposed to the surface of the buccal mucosa at high concentrations over long periods of time. The peptidase activity on the surface of the buccal mucosa has not been evaluated as a barrier to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09461358347d3f2c90ae14889affa9e6
https://doi.org/10.1016/s0378-5173(01)00934-6
https://doi.org/10.1016/s0378-5173(01)00934-6
Autor:
Gudrun Schöffmann, Hermann Kahlbacher, Sonja Franz, Nina Langoth, Andreas Bernkop-Schnürch, Maximilian Schuh, Peter Dr Kurka, I. Schmerold
Publikováno v:
Pharmaceutical research. 23(3)
Intravenous application of pituitary adenylate cyclase-activating polypeptide (PACAP) has been identified as a promising strategy for the treatment of type 2 diabetes. To generate a more applicable formulation, it was the aim of this study to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e720bcb5c8a7b648d3389e71c09c615f
https://pubmed.ncbi.nlm.nih.gov/16411147
https://pubmed.ncbi.nlm.nih.gov/16411147
Publikováno v:
International journal of pharmaceutics. 296(1-2)
The buccal mucosa providing direct entry into the systemic circulation appears to be a potential site for the delivery of PACAP (pituitary adenylate cyclase-activating polypeptide), a new therapeutic agent in the treatment of type 2 diabetes. In orde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21a485794ea323a123ed860d9e4928f
https://pubmed.ncbi.nlm.nih.gov/15885461
https://pubmed.ncbi.nlm.nih.gov/15885461
Publikováno v:
Pharmaceutical research. 20(6)
It was the purpose of this study to develop a new oral drug delivery system for low molecular weight heparin (LMWH) providing an improved bioavailability and a prolonged therapeutic effect.The permeation enhancing polycarbophil-cysteine conjugate (PC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62f14fa6e2f4e839b65b03896dcf3c17
https://pubmed.ncbi.nlm.nih.gov/12817900
https://pubmed.ncbi.nlm.nih.gov/12817900
Autor:
Nina Langoth, Hermann Kahlbacher, Gudrun Schöffmann, Ivo Schmerold, Maximilian Schuh, Sonja Franz, Peter Kurka, Andreas Bernkop-Schnürch
Publikováno v:
Pharmaceutical Research; Mar2006, Vol. 23 Issue 3, p573-579, 7p