Výsledky vyhledávání - "Nina Kerstin Wenke"

Akademický článek

sPLINK: a hybrid federated tool as a robust alternative to meta-analysis in genome-wide association studies

Autor: Reza Nasirigerdeh, Reihaneh Torkzadehmahani, Julian Matschinske, Tobias Frisch, Markus List, Julian Späth, Stefan Weiss, Uwe Völker, Esa Pitkänen, Dominik Heider, Nina Kerstin Wenke, Georgios Kaissis, Daniel Rueckert, Tim Kacprowski, Jan Baumbach

Publikováno v: Genome Biology, Vol 23, Iss 1, Pp 1-24 (2022)

Abstract Meta-analysis has been established as an effective approach to combining summary statistics of several genome-wide association studies (GWAS). However, the accuracy of meta-analysis can be attenuated in the presence of cross-study heterogene

Externí odkaz: https://doaj.org/article/3d896a9b432e4884b5b3e0f48567d7c7

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Akademický článek

CTCF and Its Multi-Partner Network for Chromatin Regulation

Autor: Aylin Del Moral-Morales, Marisol Salgado-Albarrán, Yesennia Sánchez-Pérez, Nina Kerstin Wenke, Jan Baumbach, Ernesto Soto-Reyes

Publikováno v: Cells, Vol 12, Iss 10, p 1357 (2023)

Architectural proteins are essential epigenetic regulators that play a critical role in organizing chromatin and controlling gene expression. CTCF (CCCTC-binding factor) is a key architectural protein responsible for maintaining the intricate 3D stru

Externí odkaz: https://doaj.org/article/15809eb4c25047d6a50bd975e7a1b6cb

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sPLINK: A Federated, Privacy-Preserving Tool as a Robust Alternative to Meta-Analysis in Genome-Wide Association Studies

Autor: Reza Nasirigerdeh, Reihaneh Torkzadehmahani, Julian Matschinske, Tobias Frisch, Markus List, Julian Späth, Stefan Weiß, Uwe Völker, Dominik Heider, Nina Kerstin Wenke, Tim Kacprowski, Jan Baumbach

Publikováno v: bioRxiv

Genome-wide association studies (GWAS) have been widely used to unravel connections between genetic variants and diseases. Larger sample sizes in GWAS can lead to discovering more associations and more accurate genetic predictors. However, sharing an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f02b6e6aa69e7af6ae2a996cbc635e
https://doi.org/10.1101/2020.06.05.136382