Tissue processing and optimal visualization of cerebral infarcts following sub-acute focal ischemia in rats

Autor: R. Andrew Tasker, Nina K. Iversen, Gregers Wegener, Vibeke Bay, Maryam Ardalan, Seyedeh Marziyeh Jabbari Shiadeh

Publikováno v: Bay, V, Iversen, N K, Jabbari, M, Tasker, A, Wegener, G & Ardalan, M 2021, ' Tissue processing and optimal visualization of cerebral infarcts following sub-acute focal ischemia in rats ', Journal of Chemical Neuroanatomy, vol. 118, 102034 . https://doi.org/10.1016/j.jchemneu.2021.102034

Transient cerebral ischemia followed by reperfusion in an infarcted brain comes with predictable acute and chronic morphological alterations in neuronal and non-neuronal cells. An accurate delineation of the cerebral infarct is not a simple task due

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4667ea16ce20e7950bcc00073e8600
https://pure.au.dk/portal/da/publications/tissue-processing-and-optimal-visualization-of-cerebral-infarcts-following-subacute-focal-ischemia-in-rats(9481a03c-13e7-4911-88a1-4b316e2dc7e5).html

Abstract WP326: Cortical Border Zones Are More Vulnerable to Spreading Depression-Induced Capillary Flow Disturbances

Autor: Nina K. Iversen, Turgay Dalkara, Eugenio Gutiérrez-Jiménez, Aslihan Taskiran-Sag, Leif Østergaard

Publikováno v: Stroke. 51

Cortical spreading depression (SD) is a major metabolic challenge to the brain and is followed by a unique hemodynamic response. It has been suggested that the oligemic phase of this response is accompanied by a mild to moderate capillary dysfunction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f3b5c896f7b6c80de96ed2332566c42
https://doi.org/10.1161/str.51.suppl_1.wp326

Longitudinal, Multiparametric MRI Assessment of repetitive mild TBI in rats

Autor: M Angoa-Perez, Jonas Lynge Olesen, Nina K. Iversen, Bente Krogh Hansen, Sune Nørhøj Jespersen, DM Kuhn, Leif Østergaard, Ahmad Raza Khan

Repetitive mild traumatic brain injury (mTBI) has long term health effects and may result in the development of neurodegenerative or neuropsychiatric disorders. Histology shows axonal and dendritic beading, synaptic atrophy, vasodilation and gliosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca2004d145dba49ca21f573f167010a
https://doi.org/10.1101/666024

Stroke infarct volume estimation in fixed tissue: Comparison of diffusion kurtosis imaging to diffusion weighted imaging and histology in a rodent MCAO model

Autor: Sune Nørhøj Jespersen, Kim Ryun Drasbek, Birgitte F. Kjølby, Jens R. Nyengaard, Irene Klærke Mikkelsen, Vibeke Bay, Brian Benjamin Hansen, Nina K. Iversen, Leif Østergaard, Maryam Ardalan

Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 4, p e0196161 (2018)
Bay, V, Kjølby, B F, Iversen, N K, Mikkelsen, I K, Ardalan, M, Nyengaard, J R, Jespersen, S N, Drasbek, K R, Østergaard, L & Hansen, B 2018, ' Stroke infarct volume estimation in fixed tissue : Comparison of diffusion kurtosis imaging to diffusion weighted imaging and histology in a rodent MCAO model ', PLOS ONE, vol. 13, no. 4, pp. e0196161 . https://doi.org/10.1371/journal.pone.0196161

Diffusion kurtosis imaging (DKI) is a new promising MRI technique with microstructural sensitivity superior to conventional diffusion tensor (DTI) based methods. In stroke, considerable mismatch exists between the infarct lesion outline obtained from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac49c5641760c52cbbb04a72ac82fd67
https://pubmed.ncbi.nlm.nih.gov/29698450

Capillary Transit Time Heterogeneity and Flow-Metabolism Coupling after Traumatic Brain Injury

Autor: Niels Juul, Leif Østergaard, Rasmus Aamand, Ronni Mikkelsen, Sune Nørhøj Jespersen, Anna Tietze, Brian Hansen, Jakob Udby Blicher, Jens Christian Sørensen, Irene Klærke Mikkelsen, Kim Ryun Drasbek, Thorbjørn S Engedal, Maryam Anzabi, Vibeke Bay, Erhard Trillingsgaard Næss-Schmidt, Nina K. Iversen, Mads Rasmussen

Publikováno v: Østergaard, L, Engedal, T S, Aamand, R, Mikkelsen, R, Iversen, N K, Anzabi, M, Næss-Schmidt, E, Drasbek, K R, Bay, V, Blicher, J, Tietze, A, Mikkelsen, I K, Hansen, B, Jespersen, S N, Juul, N, Sørensen, J CH & Rasmussen, M 2014, ' Capillary transit time heterogeneity and flow-metabolism coupling after traumatic brain injury ', Journal of Cerebral Blood Flow and Metabolism, vol. 34, no. 10, pp. 1585-1598 . https://doi.org/10.1038/jcbfm.2014.131
Journal of Cerebral Blood Flow & Metabolism

Most patients who die after traumatic brain injury (TBI) show evidence of ischemic brain damage. Nevertheless, it has proven difficult to demonstrate cerebral ischemia in TBI patients. After TBI, both global and localized changes in cerebral blood fl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbb96eea0e2670eaad5616496118c71
https://doi.org/10.1038/jcbfm.2014.131