Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nina Judith Hos"'
Autor:
Saray Gutiérrez, Julia Fischer, Raja Ganesan, Nina Judith Hos, Gökhan Cildir, Martina Wolke, Alberto Pessia, Peter Frommolt, Vincenzo Desiderio, Vidya Velagapudi, Nirmal Robinson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009943 (2021)
Regulation of cellular metabolism is now recognized as a crucial mechanism for the activation of innate and adaptive immune cells upon diverse extracellular stimuli. Macrophages, for instance, increase glycolysis upon stimulation with pathogen-associ
Externí odkaz:
https://doaj.org/article/b990dc2fb1bd4d26bb009ef804bbfd30
Autor:
Uduak Okomo, PhD, Madikay Senghore, PhD, Saffiatou Darboe, MSc, Ebrima Bojang, MRes, Syed M A Zaman, PhD, Mohammad Jahangir Hossain, MBBS, Davis Nwakanma, PhD, Kirsty Le Doare, PhD, Kathryn E Holt, ProfPhD, Nina Judith Hos, MD, Joy E Lawn, ProfFMedSCi, Stephen D Bentley, PhD, Beate Kampmann, ProfPhD
Publikováno v:
The Lancet Microbe, Vol 1, Iss 3, Pp e119-e129 (2020)
Summary: Background: Sick newborns admitted to neonatal units in low-resource settings are at an increased risk of developing hospital-acquired infections due to poor clinical care practices. Clusters of infection, due to the same species, with a con
Externí odkaz:
https://doaj.org/article/05e282d9f1634a239738fef3154fbf22
Autor:
Raja Ganesan, Nina Judith Hos, Saray Gutierrez, Julia Fischer, Joanna Magdalena Stepek, Evmorphia Daglidu, Martin Krönke, Nirmal Robinson
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006227 (2017)
During intracellular infections, autophagy significantly contributes to the elimination of pathogens, regulation of pro-inflammatory signaling, secretion of immune mediators and in coordinating the adaptive immune system. Intracellular pathogens such
Externí odkaz:
https://doaj.org/article/88951ac5b7db4cf88e395f26c362ac3a
Autor:
Chiara Calabrese, Jan Rybniker, Sharad Kumar, Nirmal Robinson, Nina Judith Hos, Julia Fischer, Zahra Hejazi, Deniz Hos, Raja Ganesan, Martin Krönke, Ambika M. V. Murthy
Publikováno v:
J Immunol
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a Gram-negative bacterium that induces cell death of macrophages as a key virulence strategy. We have previously demonstrated that the induction of macrophage death is dependent on the host
Autor:
Madikay Senghore, Stephen D. Bentley, Ebrima Bojang, Nina Judith Hos, Uduak Okomo, Mohammad Jahangir Hossain, Joy E Lawn, Beate Kampmann, Kathryn E. Holt, Saffiatou Darboe, Syed M. A. Zaman, Kirsty Le Doare, Davis Nwakanma
Publikováno v:
The Lancet Microbe, Vol 1, Iss 3, Pp e119-e129 (2020)
Summary Background Sick newborns admitted to neonatal units in low-resource settings are at an increased risk of developing hospital-acquired infections due to poor clinical care practices. Clusters of infection, due to the same species, with a consi
Autor:
Martina Wolke, Raja Ganesan, Saray Gutiérrez, Gökhan Cildir, Jochen W.U. Fries, Nirmal Robinson, Julia Fischer, Vinay Tergaonkar, Adam Antebi, Chiara Calabrese, Jan Rybniker, Rajeev Ranjan, Georg Plum, Nina Judith Hos
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance In the present study, we identify and describe an important cross-talk between leptin signaling and macrophage functions in the context of Salmonella Typhimurium infection. Genetic ablation of leptin receptor or pharmacological antagoniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c712a8d2adc890baf4ebffbc0d84a77
https://hdl.handle.net/21.11116/0000-000B-42FF-C
https://hdl.handle.net/21.11116/0000-000B-42FF-C
Autor:
Thorsten Simon, Anja Möricke, Lars Tharun, Axel Hamprecht, Martin Dübbers, Janina Fischer, Nina Judith Hos, Bernd Gruhn, Grigore Cernaianu, Georg Plum
Publikováno v:
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie. 28(6)
Background The incidence of invasive aspergillosis (IA) in children with hematooncological malignancies is increasing as a result of intensive treatment, immunosuppression, and extended use of broad-spectrum antibiotics. Infection of the GI tract by
Autor:
Nina Judith Hos, Joanna Magdalena Stepek, Nirmal Robinson, Evmorphia Daglidu, Raja Ganesan, Martin Krönke, Saray Gutiérrez, Julia Fischer
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 2, p e1006227 (2017)
PLoS Pathogens, Vol 13, Iss 2, p e1006227 (2017)
During intracellular infections, autophagy significantly contributes to the elimination of pathogens, regulation of pro-inflammatory signaling, secretion of immune mediators and in coordinating the adaptive immune system. Intracellular pathogens such
Autor:
Zeinab Abdullah, Raja Ganesan, Deniz Hos, Jennifer Klimek, Saray Gutiérrez, Nina Judith Hos, Nirmal Robinson, Martin Krönke
Publikováno v:
Cell Stress
The Journal of Cell Biology
The Journal of Cell Biology
Type I interferon (IFN-I) triggers necroptosis in macrophages infected with S. Typhimurium by an unclear mechanism. Hos et al. now demonstrate that RIP3 enhances the interaction of Nrf2 with Pgam5 in response to IFN-I signaling in S. Typhimurium–in
Publikováno v:
European journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology. 35(9)
We evaluated two fully-automated real-time PCR systems, the novel QIAGEN artus MRSA/SA QS-RGQ and the widely used BD MAX MRSA assay, for their diagnostic performance in MRSA admission screening in a tertiary-care university hospital. Two hundred sixt