Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Nina Iversen"'
Autor:
Nina Iversen, Carola Elisabeth Henriksson, Marit Sletten, Marie Skogstad Le, Beate Rikken Lindberg, Rune Andersen, Benedicte Paus
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-5 (2024)
Abstract Background Atresia of the infrarenal inferior vena cava (IVC) is associated with thrombophilia and antithrombin (AT) deficiency (ATD) due to homozygosity for the so-called Budapest 3 variant, c.391C > T, in the gene, SERPINC1. Case presentat
Externí odkaz:
https://doaj.org/article/a949bc1e11ec48edbd86983aaf3048e9
Autor:
Nicola Bassi, Henrikke Nilsen Hovland, Kashif Rasheed, Elisabeth Jarhelle, Nikara Pedersen, Eunice Kabanyana Mchaina, Sara Marie Engelsvold Bakkan, Nina Iversen, Hildegunn Høberg-Vetti, Bjørn Ivar Haukanes, Per Morten Knappskog, Ingvild Aukrust, Elisabet Ognedal, Marijke Van Ghelue
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Damaging alterations in the BRCA1 gene have been extensively described as one of the main causes of hereditary breast and ovarian cancer (HBOC). BRCA1 alterations can lead to impaired homologous recombination repair (HRR) of doubl
Externí odkaz:
https://doaj.org/article/3cfc411134d040d8a50b6bbb38b22097
Autor:
Xue Yan Cui, Geir Erland Tjønnfjord, Sandip M. Kanse, Anders Erik Astrup Dahm, Nina Iversen, Christiane Filion Myklebust, Ling Sun, Zhong Xing Jiang, Thor Ueland, James J. Campbell, Mitchell Ho, Per Morten Sandset
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The infiltration of chronic lymphocytic leukemia (CLL) cells into lymphoid organs correlates with disease severity. CXCL12 is a key chemotactic factor for the trafficking of CLL. Tissue factor pathway inhibitor (TFPI) is a serine protease in
Externí odkaz:
https://doaj.org/article/ce0caf0c3fe64d058cc6da40b15f9c56
Publikováno v:
Human Genomics, Vol 12, Iss 1, Pp 1-13 (2018)
Abstract Background Deleterious variants in the tumour suppressor BRCA1 are known to cause hereditary breast and ovarian cancer syndrome (HBOC). Missense variants in BRCA1 pose a challenge in clinical care, as their effect on protein functionality of
Externí odkaz:
https://doaj.org/article/75838fdb553a4de2a0d3394804b44b21
Publikováno v:
Case Reports in Obstetrics and Gynecology, Vol 2021 (2021)
Pregnancy is associated with an increased risk of venous thromboembolism (VTE). Previous VTE and severe thrombophilia are important risk factors. Our case was a 36-year-old woman, gravida 6, para 0, with antithrombin (AT) deficiency caused by a homoz
Externí odkaz:
https://doaj.org/article/7e55ef0be70a481d98aa98cef6492853
Autor:
Huda Omar Ali, Benedicte Stavik, Christiane Filion Myklebust, Elisabeth Andersen, Anders E A Dahm, Nina Iversen, Per Morten Sandset, Grethe Skretting
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152114 (2016)
Oestrogens influence the pathology and development of hormone-sensitive breast cancers. Tissue factor pathway inhibitor (TFPI) has been shown to be associated with breast cancer pathogenesis. Recently, we found TFPI mRNA levels to be significantly re
Externí odkaz:
https://doaj.org/article/da25db980d864c6dbc7931d409b2db49
Autor:
Mari Tinholt, Benedicte Stavik, William Louch, Cathrine Rein Carlson, Marit Sletten, Wolfram Ruf, Grethe Skretting, Per Morten Sandset, Nina Iversen
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0117404 (2015)
BACKGROUND:Tissue factor (TF) pathway inhibitor (TFPI) exists in two isoforms; TFPIα and TFPIβ. Both isoforms are cell surface attached mainly through glycosylphosphatidylinositol (GPI) anchors. TFPIα has also been proposed to bind other surface m
Externí odkaz:
https://doaj.org/article/b0a4d2d9f1324f26b268d614c2ab7d6c
Autor:
Hanne A Askautrud, Elisabet Gjernes, Gjermund Gunnes, Marit Sletten, Douglas T Ross, Anne Lise Børresen-Dale, Nina Iversen, Michael A Tranulis, Eirik Frengen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87268 (2014)
N-myc downstream-regulated gene 1 (NDRG1) is induced by cellular stress such as hypoxia and DNA damage, and in humans, germ line mutations cause Charcot-Marie-Tooth disease. However, the cellular roles of NDRG1 are not fully understood. Previously, N
Externí odkaz:
https://doaj.org/article/810df7ac7d194cba9b212c8e6d0e08c8
Autor:
Benedicte Stavik, Grethe Skretting, Ole Kristoffer Olstad, Marit Sletten, Magnus Dehli Vigeland, Per Morten Sandset, Nina Iversen
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47184 (2012)
Emerging evidence indicate a new role of TFPI in cancer biology. We recently reported that both isoforms of TFPI induced apoptosis and inhibited proliferation of cancer cells. The signaling pathway(s) mediating the effects of TFPI is, however, presen
Externí odkaz:
https://doaj.org/article/b30a66be188c455ea65a6ebbf77fa915
Autor:
Lena Tjeldhorn, Nina Iversen, Kirsten Sandvig, Jonas Bergan, Per Morten Sandset, Grethe Skretting
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e24009 (2011)
BACKGROUND: Protein C (PC) deficiency is associated with a high risk of venous thrombosis. Recently, we identified the PC-A267T mutation in a patient with PC deficiency and revealed by in vitro studies decreased intracellular and secreted levels of t
Externí odkaz:
https://doaj.org/article/a203a448586343ae9abe61329060c98d