Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Nina Ilic"'
Autor:
Chao Dai, Jonathan P. Rennhack, Taylor E. Arnoff, Maneesha Thaker, Scott T. Younger, John G. Doench, August Yue Huang, Annan Yang, Andrew J. Aguirre, Belinda Wang, Evan Mun, Joyce T. O’Connell, Ying Huang, Katherine Labella, Jessica A. Talamas, Ji Li, Nina Ilic, Justin Hwang, Andrew L. Hong, Andrew O. Giacomelli, Ole Gjoerup, David E. Root, William C. Hahn
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109443- (2021)
Summary: Metastasis is a complex and poorly understood process. In pancreatic cancer, loss of the transforming growth factor (TGF)-β/BMP effector SMAD4 is correlated with changes in altered histopathological transitions, metastatic disease, and poor
Externí odkaz:
https://doaj.org/article/576815dfcfd2415692f51077629b4730
Autor:
Ji Li, Peter S Choi, Christine L Chaffer, Katherine Labella, Justin H Hwang, Andrew O Giacomelli, Jong Wook Kim, Nina Ilic, John G Doench, Seav Huong Ly, Chao Dai, Kimberly Hagel, Andrew L Hong, Ole Gjoerup, Shom Goel, Jennifer Y Ge, David E Root, Jean J Zhao, Angela N Brooks, Robert A Weinberg, William C Hahn
Publikováno v:
eLife, Vol 7 (2018)
Alternative splicing of mRNA precursors represents a key gene expression regulatory step and permits the generation of distinct protein products with diverse functions. In a genome-scale expression screen for inducers of the epithelial-to-mesenchymal
Externí odkaz:
https://doaj.org/article/065b7c78b0bc49f4914d3e34a00422d9
Autor:
Elsa Beyer Krall, Belinda Wang, Diana M Munoz, Nina Ilic, Srivatsan Raghavan, Matthew J Niederst, Kristine Yu, David A Ruddy, Andrew J Aguirre, Jong Wook Kim, Amanda J Redig, Justin F Gainor, Juliet A Williams, John M Asara, John G Doench, Pasi A Janne, Alice T Shaw, Robert E McDonald III III, Jeffrey A Engelman, Frank Stegmeier, Michael R Schlabach, William C Hahn
Publikováno v:
eLife, Vol 6 (2017)
Externí odkaz:
https://doaj.org/article/97e06b1cb72c431b99c9fe722c7f8112
Autor:
Elsa B Krall, Belinda Wang, Diana M Munoz, Nina Ilic, Srivatsan Raghavan, Matthew J Niederst, Kristine Yu, David A Ruddy, Andrew J Aguirre, Jong Wook Kim, Amanda J Redig, Justin F Gainor, Juliet A Williams, John M Asara, John G Doench, Pasi A Janne, Alice T Shaw, Robert E McDonald III, Jeffrey A Engelman, Frank Stegmeier, Michael R Schlabach, William C Hahn
Publikováno v:
eLife, Vol 6 (2017)
Inhibitors that target the receptor tyrosine kinase (RTK)/Ras/mitogen-activated protein kinase (MAPK) pathway have led to clinical responses in lung and other cancers, but some patients fail to respond and in those that do resistance inevitably occur
Externí odkaz:
https://doaj.org/article/91aa16d9c6ee4f3db98bf405c26f0785
Autor:
William C. Hahn, Rameen Beroukhim, Jill P. Mesirov, Pablo Tamayo, Levi A. Garraway, Barbara A. Weir, Craig H. Mermel, David A. Barbie, Nicole A. Spardy, Anna C. Schinzel, Joseph Rosenbluh, Andrew O. Giacomelli, So Young Kim, Yashaswi Shrestha, Francisca Vazquez, Hiu Wing Cheung, Rhine R. Shen, Nina Ilic, Steven E. Schumacher, Alexander Tong, Daniel Hagerstrand
Supplementary Table S7 - XLSX file 61K, List of shRNAs used in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539e3f37dc54f1394b78b7a5239319d9
https://doi.org/10.1158/2159-8290.22530869.v1
https://doi.org/10.1158/2159-8290.22530869.v1
Autor:
William C. Hahn, Rameen Beroukhim, Jill P. Mesirov, Pablo Tamayo, Levi A. Garraway, Barbara A. Weir, Craig H. Mermel, David A. Barbie, Nicole A. Spardy, Anna C. Schinzel, Joseph Rosenbluh, Andrew O. Giacomelli, So Young Kim, Yashaswi Shrestha, Francisca Vazquez, Hiu Wing Cheung, Rhine R. Shen, Nina Ilic, Steven E. Schumacher, Alexander Tong, Daniel Hagerstrand
Supplementary Figure 2 - PDF file 17K, SKIL induces Matrigel invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6814bc75209190364fc2339cd40524b
https://doi.org/10.1158/2159-8290.22530896.v1
https://doi.org/10.1158/2159-8290.22530896.v1
Autor:
William C. Hahn, Jesse S. Boehm, Gad Getz, Todd R. Golub, Aravind Subramanian, David E. Root, Kasper Lage, Steven M. Corsello, Heiko Horn, Pablo Tamayo, Ted Natoli, Larson Hogstrom, Xiaoyun Wu, Candace R. Chouinard, John G. Doench, Mukta Bagul, Federica Piccioni, Michael S. Lawrence, Cindy Nguyen, Nancy Tran, Rakela Lubonja, Xiaoping Yang, Cong Zhu, Atanas Kamburov, Lihua Zou, Yashaswi Shrestha, Nina Ilic, Eejung Kim
Pool composition of in vivo screen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9a9e71a7ebad674dbc9abf9856af67
https://doi.org/10.1158/2159-8290.22531040.v1
https://doi.org/10.1158/2159-8290.22531040.v1
Autor:
William C. Hahn, Jesse S. Boehm, Gad Getz, Todd R. Golub, Aravind Subramanian, David E. Root, Kasper Lage, Steven M. Corsello, Heiko Horn, Pablo Tamayo, Ted Natoli, Larson Hogstrom, Xiaoyun Wu, Candace R. Chouinard, John G. Doench, Mukta Bagul, Federica Piccioni, Michael S. Lawrence, Cindy Nguyen, Nancy Tran, Rakela Lubonja, Xiaoping Yang, Cong Zhu, Atanas Kamburov, Lihua Zou, Yashaswi Shrestha, Nina Ilic, Eejung Kim
Supplementary Figure S1. Distribution of barcode read representation in pre-expansion and pre-injection samples. Supplementary Figure S2. Tumor composition of in vivo pooled screen, excluding the pools shown in Figure 2. Supplementary Figure S3. Gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3834e791550f6212cdd18850abe1488e
https://doi.org/10.1158/2159-8290.22531052.v1
https://doi.org/10.1158/2159-8290.22531052.v1
Autor:
William C. Hahn, Rameen Beroukhim, Jill P. Mesirov, Pablo Tamayo, Levi A. Garraway, Barbara A. Weir, Craig H. Mermel, David A. Barbie, Nicole A. Spardy, Anna C. Schinzel, Joseph Rosenbluh, Andrew O. Giacomelli, So Young Kim, Yashaswi Shrestha, Francisca Vazquez, Hiu Wing Cheung, Rhine R. Shen, Nina Ilic, Steven E. Schumacher, Alexander Tong, Daniel Hagerstrand
Supplementary Legends - PDF file 122K, Legends for all Supplementary information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c208369df286445bbe6c54753787d95f
https://doi.org/10.1158/2159-8290.22530890.v1
https://doi.org/10.1158/2159-8290.22530890.v1
Autor:
William C. Hahn, Rameen Beroukhim, Jill P. Mesirov, Pablo Tamayo, Levi A. Garraway, Barbara A. Weir, Craig H. Mermel, David A. Barbie, Nicole A. Spardy, Anna C. Schinzel, Joseph Rosenbluh, Andrew O. Giacomelli, So Young Kim, Yashaswi Shrestha, Francisca Vazquez, Hiu Wing Cheung, Rhine R. Shen, Nina Ilic, Steven E. Schumacher, Alexander Tong, Daniel Hagerstrand
Supplementary Figure 3 - PDF file 20K, 3q26 copy number in cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19945af4ebfde8f67e16efee4cabe9e7
https://doi.org/10.1158/2159-8290.22530893.v1
https://doi.org/10.1158/2159-8290.22530893.v1