Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Nina Hobi"'
Autor:
Estelle Marrer-Berger, Annalisa Nicastri, Angelique Augustin, Vesna Kramar, Hanqing Liao, Lydia Jasmin Hanisch, Alejandro Carpy, Tina Weinzierl, Evelyne Durr, Nathalie Schaub, Ramona Nudischer, Daniela Ortiz-Franyuti, Ekaterina Breous-Nystrom, Janick Stucki, Nina Hobi, Giulia Raggi, Lauriane Cabon, Emmanuelle Lezan, Pablo Umaña, Isaac Woodhouse, Alexander Bujotzek, Christian Klein, Nicola Ternette
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Selective binding of TCR-like antibodies that target a single tumour-specific peptide antigen presented by human leukocyte antigens (HLA) is the absolute prerequisite for their therapeutic suitability and patient safety. To date, selectivity
Externí odkaz:
https://doaj.org/article/1e7a4a6f3006436c814053de1558d191
Autor:
Arunima Sengupta, Aurélien Dorn, Mohammad Jamshidi, Magali Schwob, Widad Hassan, Lea Lara De Maddalena, Andreas Hugi, Andreas O. Stucki, Patrick Dorn, Thomas M. Marti, Oliver Wisser, Janick D. Stucki, Tobias Krebs, Nina Hobi, Olivier T. Guenat
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Prolonged exposure to environmental respirable toxicants can lead to the development and worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD) and fibrosis. The limited number of FDA-approved inhaled dr
Externí odkaz:
https://doaj.org/article/c791da18c4f74563afefe4f78478af93
Autor:
Arunima Sengupta, Nuria Roldan, Mirjam Kiener, Laurène Froment, Giulia Raggi, Theo Imler, Lea de Maddalena, Aude Rapet, Tobias May, Patrick Carius, Nicole Schneider-Daum, Claus-Michael Lehr, Marianna Kruithof-de Julio, Thomas Geiser, Thomas Michael Marti, Janick D. Stucki, Nina Hobi, Olivier T. Guenat
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
The evaluation of inhalation toxicity, drug safety and efficacy assessment, as well as the investigation of complex disease pathomechanisms, are increasingly relying on in vitro lung models. This is due to the progressive shift towards human-based sy
Externí odkaz:
https://doaj.org/article/18439d6b7ad04cbb88aed125762e6885
Autor:
Pauline Zamprogno, Simon Wüthrich, Sven Achenbach, Giuditta Thoma, Janick D. Stucki, Nina Hobi, Nicole Schneider-Daum, Claus-Michael Lehr, Hanno Huwer, Thomas Geiser, Ralph A. Schmid, Olivier T. Guenat
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Zamprogno et al. report a lung-on-a-chip of the second generation that mimics an array of alveoli with in vivo-like dimensions, based on a thin, stretchable collagen-elastin membrane used to reproduce the air-blood barrier functions. The membrane is
Externí odkaz:
https://doaj.org/article/b58e7abc6fe5449390fc885d757f1445
Autor:
Kristina Krempaska, Sandra Barnowski, Jacopo Gavini, Nina Hobi, Simone Ebener, Cedric Simillion, Andrea Stokes, Ronja Schliep, Lars Knudsen, Thomas K. Geiser, Manuela Funke-Chambour
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic fatal lung disease without a cure and new drug strategies are urgently needed. Differences in behavior between diseased and healthy cells are well known and drug response can be dif
Externí odkaz:
https://doaj.org/article/19ef359e4b5940cfae9770024a8b6cc1
Autor:
Colin Charles Tièche, Yanyun Gao, Elias Daniel Bührer, Nina Hobi, Sabina Anna Berezowska, Kurt Wyler, Laurène Froment, Stefan Weis, Ren-Wang Peng, Rémy Bruggmann, Primo Schär, Michael Alex Amrein, Sean Ralph Robert Hall, Patrick Dorn, Gregor Kocher, Carsten Riether, Adrian Ochsenbein, Ralph Alexander Schmid, Thomas Michael Marti
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 2, Pp 185-196 (2019)
Cell lines are essential tools to standardize and compare experimental findings in basic and translational cancer research. The current dogma states that cancer stem cells feature an increased tumor initiation capacity and are also chemoresistant. He
Externí odkaz:
https://doaj.org/article/8bc1f63887234260ade852cc5b8ad7cb
Autor:
Mirjam Kiener, Nuria Roldan, Carlos Machahua, Arunima Sengupta, Thomas Geiser, Olivier Thierry Guenat, Manuela Funke-Chambour, Nina Hobi, Marianna Kruithof-de Julio
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
The coronavirus disease 2019 (COVID-19) pandemic has caused considerable socio-economic burden, which fueled the development of treatment strategies and vaccines at an unprecedented speed. However, our knowledge on disease recovery is sparse and conc
Externí odkaz:
https://doaj.org/article/cb4604d607294666a80996f8de2bc914
Autor:
Kristina Krempaska, Sandra Barnowski, Jacopo Gavini, Nina Hobi, Simone Ebener, Cedric Simillion, Andrea Stokes, Ronja Schliep, Lars Knudsen, Thomas K. Geiser, Manuela Funke-Chambour
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-1 (2020)
After publication of our article [1], we have been notified that an extra alpha symbol (α) was mistakenly added at the beginning of the title.
Externí odkaz:
https://doaj.org/article/692651b2c6af4217b910ad13c7eef1f7
Autor:
Pika Miklavc, Konstantin Ehinger, Kristin E Thompson, Nina Hobi, Derya R Shimshek, Manfred Frick
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84926 (2014)
Leucine-rich repeat kinase 2 (LRRK2) is known to play a role in the pathogenesis of various diseases including Parkinson disease, morbus Crohn, leprosy and cancer. LRRK2 is suggested to be involved in a number of cell biological processes such as ves
Externí odkaz:
https://doaj.org/article/a9153f2f03e242cc91677595d7fa74e4
Autor:
Nina Hobi, Olivier T. Guenat, Janick Stucki, Oliver Wisser, Tobias Krebs, Arunima Sengupta, Patrick Weindl, Nuria Roldan, Magali Schwob
Publikováno v:
Mechanisms of lung injury and repair.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8c33195741d323018256e53b1bd6404
https://doi.org/10.1183/13993003.congress-2021.pa2053
https://doi.org/10.1183/13993003.congress-2021.pa2053