Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nina Geib"'
Autor:
Marco Tamborrini, Nina Geib, Aniebrys Marrero-Nodarse, Maja Jud, Julia Hauser, Celestine Aho, Araceli Lamelas, Armando Zuniga, Gerd Pluschke, Arin Ghasparian, John A. Robinson
Publikováno v:
Vaccines, Vol 3, Iss 4, Pp 850-874 (2015)
Alternatives to the well-established capsular polysaccharide-based vaccines against Streptococcus pneumoniae that circumvent limitations arising from limited serotype coverage and the emergence of resistance due to capsule switching (serotype replace
Externí odkaz:
https://doaj.org/article/bd3ac40b3b114e489cb401e7e801ed34
Autor:
Aniebrys Marrero-Nodarse, Julia Hauser, Gerd Pluschke, Armando Zuniga, Arin Ghasparian, Marco Tamborrini, Maja Jud, John A. Robinson, Nina Geib, Araceli Lamelas, Celestine Aho
Publikováno v:
Vaccines
Volume 3
Issue 4
Pages 850-874
Vaccines, Vol 3, Iss 4, Pp 850-874 (2015)
Volume 3
Issue 4
Pages 850-874
Vaccines, Vol 3, Iss 4, Pp 850-874 (2015)
Alternatives to the well-established capsular polysaccharide-based vaccines against Streptococcus pneumoniae that circumvent limitations arising from limited serotype coverage and the emergence of resistance due to capsule switching (serotype replace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af85d33203f484e1db608e81bbb0b0c
http://europepmc.org/articles/PMC4693222
http://europepmc.org/articles/PMC4693222
Publikováno v:
FEMS microbiology letters
Ferredoxins are required to supply electrons to the cytochrome P450 enzymes involved in cross-linking reactions during the biosynthesis of the glycopeptide antibiotics balhimycin and vancomycin. However, the biosynthetic gene clusters for these antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56943556cccc863d997870160394af6
https://doi.org/10.1111/j.1574-6968.2010.01933.x
https://doi.org/10.1111/j.1574-6968.2010.01933.x
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:3081-3084
OxyB catalyzes the first oxidative phenol coupling reaction in vancomycin biosynthesis. OxyB is a P450 hemoprotein whose activity is strictly dependent upon the presence of molecular oxygen. Here, it was shown that label from (18)O(2) is not incorpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e50e2a50ebfc8f34f8517e4d0579c7
https://doi.org/10.1016/j.bmcl.2007.11.093
https://doi.org/10.1016/j.bmcl.2007.11.093
Autor:
Dong Bo, Li, Katharina, Woithe, Nina, Geib, Khaled, Abou-Hadeed, Katja, Zerbe, John A, Robinson
Publikováno v:
Methods in enzymology
Oxidative phenol cross-linking reactions play a key role in the biosynthesis of glycopeptide antibiotics such as vancomycin. The vancomycin aglycone contains three cross-links between aromatic amino acid side-chains, which stabilize the folded backbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d79b8a176382fb490e8b81fc714cad95
https://www.zora.uzh.ch/id/eprint/24908/
https://www.zora.uzh.ch/id/eprint/24908/
Oxidative phenol cross-linking reactions play a key role in the biosynthesis of glycopeptide antibiotics such as vancomycin. The vancomycin aglycone contains three cross-links between aromatic amino acid side-chains, which stabilize the folded backbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dcd38197c73792f53b3d290b80e8b15
https://doi.org/10.1016/s0076-6879(09)04819-8
https://doi.org/10.1016/s0076-6879(09)04819-8
Autor:
Odile Meyer, Nina Geib, Severine Fournier-Rousset, Francesca Vitali, Katharina Woithe, Nobuatsu Matoba, John A. Robinson, Dong Bo Li, Katja Zerbe, Khaled Abou-Hadeed, Markus Heck
Publikováno v:
Journal of the American Chemical Society. 129(21)
OxyB is a cytochrome P450 enzyme that catalyzes the first phenol coupling reaction during the biosynthesis of vancomycin-like glycopeptide antibiotics. The phenol coupling reaction occurs on a linear peptide intermediate linked as a C-terminal thioes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f6422287a45c85c6d5fb5e1bb7a97c
https://pubmed.ncbi.nlm.nih.gov/17477533
https://pubmed.ncbi.nlm.nih.gov/17477533
Publikováno v:
The Journal of organic chemistry. 72(10)
Aminopyrazole derivatives constitute the first class of nonpeptidic rationally designed beta-sheet ligands. Here we describe a double solid-phase protocol for both synthesis and affinity testing. The presented solid-phase synthesis of four types of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a770cdc6455ff72af4501f8c64fb860
https://pubmed.ncbi.nlm.nih.gov/17428094
https://pubmed.ncbi.nlm.nih.gov/17428094
Publikováno v:
Organic & Biomolecular Chemistry. 6:2861
OxyB is a cytochrome P450 enzyme that catalyzes the first oxidative phenol coupling reaction during vancomycin biosynthesis. The preferred substrate is a linear peptide linked as a C-terminal thioester to a peptide carrier protein (PCP) domain of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6360aa2ed480eb9d63c8c94479d4c54
https://doi.org/10.1039/b805956j
https://doi.org/10.1039/b805956j