Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nina Gasparoni"'
Autor:
Ranjan Kumar Maji, Beate Czepukojc, Michael Scherer, Sascha Tierling, Cristina Cadenas, Kathrin Gianmoena, Nina Gasparoni, Karl Nordström, Gilles Gasparoni, Stephan Laggai, Xinyi Yang, Anupam Sinha, Peter Ebert, Maren Falk-Paulsen, Sarah Kinkley, Jessica Hoppstädter, Ho-Ryun Chung, Philip Rosenstiel, Jan G. Hengstler, Jörn Walter, Marcel H. Schulz, Sonja M. Kessler, Alexandra K. Kiemer
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Fatty liver disease or the accumulation of fat in the liver, has been reported to affect the global population. This comes with an increased risk for the development of fibrosis, cirrhosis, and hepatocellular carcinoma. Yet, little is known
Externí odkaz:
https://doaj.org/article/08abcdc296d74786a777114970ddef43
Autor:
Denise Beckmann, Anja Römer-Hillmann, Annika Krause, Uwe Hansen, Corinna Wehmeyer, Johanna Intemann, David J. J. de Gorter, Berno Dankbar, Jan Hillen, Marianne Heitzmann, Isabell Begemann, Milos Galic, Toni Weinhage, Dirk Foell, Rizi Ai, Joachim Kremerskothen, Hans P. Kiener, Sylvia Müller, Thomas Kamradt, Christopher Schröder, Elsa Leitão, Bernhard Horsthemke, Philip Rosenstiel, Karl Nordström, Gilles Gasparoni, Nina Gasparoni, Jörn Walter, Na Li, Xinyi Yang, Ho-Ryun Chung, Hermann Pavenstädt, Nico Lindemann, Hans J. Schnittler, Wei Wang, Gary S. Firestein, Thomas Pap, Adelheid Korb-Pap
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Fibroblast-like synoviocytes are important mediators of joint pathology in rheumatoid arthritis (RA). Here the authors show that Lasp1 is epigenetically regulated and highly expressed by these cells in RA and its deletion can limit joint pathology in
Externí odkaz:
https://doaj.org/article/6eeabbe32b3249c9843c922ebc496340
Autor:
Kathrin Gianmoena, Nina Gasparoni, Adelina Jashari, Philipp Gabrys, Katharina Grgas, Ahmed Ghallab, Karl Nordström, Gilles Gasparoni, Jörg Reinders, Karolina Edlund, Patricio Godoy, Alexander Schriewer, Heiko Hayen, Christian A. Hudert, Georg Damm, Daniel Seehofer, Thomas S. Weiss, Peter Boor, Hans-Joachim Anders, Manga Motrapu, Peter Jansen, Tobias S. Schiergens, Maren Falk-Paulsen, Philip Rosenstiel, Clivia Lisowski, Eduardo Salido, Rosemarie Marchan, Jörn Walter, Jan G. Hengstler, Cristina Cadenas
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109526- (2021)
Summary: Epigenetic modifications (e.g. DNA methylation) in NAFLD and their contribution to disease progression and extrahepatic complications are poorly explored. Here, we use an integrated epigenome and transcriptome analysis of mouse NAFLD hepatoc
Externí odkaz:
https://doaj.org/article/8d9cdcdc3d35492a92af90d5a6d5d7cb
Autor:
Anna Ramisch, Verena Heinrich, Laura V. Glaser, Alisa Fuchs, Xinyi Yang, Philipp Benner, Robert Schöpflin, Na Li, Sarah Kinkley, Anja Römer-Hillmann, John Longinotto, Steffen Heyne, Beate Czepukojc, Sonja M. Kessler, Alexandra K. Kiemer, Cristina Cadenas, Laura Arrigoni, Nina Gasparoni, Thomas Manke, Thomas Pap, John A. Pospisilik, Jan Hengstler, Jörn Walter, Sebastiaan H. Meijsing, Ho-Ryun Chung, Martin Vingron
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-23 (2019)
Abstract We present the software Condition-specific Regulatory Units Prediction (CRUP) to infer from epigenetic marks a list of regulatory units consisting of dynamically changing enhancers with their target genes. The workflow consists of a novel pr
Externí odkaz:
https://doaj.org/article/0837b27a1c654e23a698084a3171e903
Autor:
Fatemeh Behjati Ardakani, Kathrin Kattler, Karl Nordström, Nina Gasparoni, Gilles Gasparoni, Sarah Fuchs, Anupam Sinha, Matthias Barann, Peter Ebert, Jonas Fischer, Barbara Hutter, Gideon Zipprich, Charles D. Imbusch, Bärbel Felder, Jürgen Eils, Benedikt Brors, Thomas Lengauer, Thomas Manke, Philip Rosenstiel, Jörn Walter, Marcel H. Schulz
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-14 (2018)
Abstract Background Bidirectional promoters (BPs) are prevalent in eukaryotic genomes. However, it is poorly understood how the cell integrates different epigenomic information, such as transcription factor (TF) binding and chromatin marks, to drive
Externí odkaz:
https://doaj.org/article/aeda19e919924fcba37b9cf5784814fb
Autor:
Marcel H. Schulz, Nina Gasparoni, Karl Nordström, Gilles Gasparoni, Stephan Laggai, Xinyi Yang, Anupam Sinha, Peter Ebert, Maren Falk-Paulsen, Sarah Kinkley, Ho-Ryun Chung, Philip Rosenstiel, Jan G. Hengstler, Jörn Walter, Sonja M. Kessler, Alexandra K. Kiemer, Ranjan Kumar Maji, Beate Czepukojc, Michael Scherer, Sascha Tierling
Fatty liver disease or the buildup of fat in the liver, has been reported to affect the global population. This comes with an increased risk for the development of fibrosis, cirrhosis, and hepatocellular carcinoma. Yet, little is known about the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6252f9941037ffbe0378d2b7b2f7ebc5
https://doi.org/10.21203/rs.3.rs-2711309/v1
https://doi.org/10.21203/rs.3.rs-2711309/v1
Autor:
Cristina Cadenas, Kathrin Gianmoena, Nina Gasparoni, Adelina Jashari, Philipp Gabrys, Ahmed Ghallab, Katharina Grgas, Jörn Walter, Jan Hengstler
Publikováno v:
Zeitschrift für Gastroenterologie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7d1babe9d1aa3aab862eac82cf87ebf
https://doi.org/10.1055/s-0041-1740734
https://doi.org/10.1055/s-0041-1740734
Autor:
Rizi Ai, Uwe Hansen, Johanna Intemann, Elsa Leitão, Toni Weinhage, Isabell Begemann, Joachim Kremerskothen, Anja Römer-Hillmann, Ho-Ryun Chung, Marianne Heitzmann, Thomas Pap, Hermann Pavenstädt, Hans P. Kiener, Na Li, Annika Krause, Wei Wang, Gilles Gasparoni, Berno Dankbar, Sylvia Müller, Corinna Wehmeyer, Denise Beckmann, Dirk Foell, Philip Rosenstiel, Bernhard Horsthemke, Thomas Kamradt, Adelheid Korb-Pap, Karl Nordström, Hans Schnittler, David J. J. de Gorter, Nico Lindemann, Jörn Walter, Gary S. Firestein, Xinyi Yang, Nina Gasparoni, Christopher Schröder, Jan Hillen, Milos Galic
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The LIM and SH3 domain protein 1 (Lasp1) was originally cloned from metastatic breast cancer and characterised as an adaptor molecule associated with tumourigenesis and cancer cell invasion. However, the regulation of Lasp1 and its function in the ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186d00758ac40be110c81701778639ee
http://europepmc.org/articles/PMC8206096
http://europepmc.org/articles/PMC8206096
Autor:
Jörn Walter, Nina Gasparoni
Publikováno v:
Fünfter Gentechnologiebericht
Die Epigenetik hat sich Jörn Walter und Nina Gasparoni zufolge in den vergangenen zwei Jahrzehnten zu einem Kernfach der Lebenswissenschaften entwickelt und eine breite Strahlkraft in nahezu alle Bereiche der Biologie und Biomedizin entfaltet. Epige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b493244e438f31a4b7f5204f38ea4c95
https://doi.org/10.5771/9783748927242-93
https://doi.org/10.5771/9783748927242-93
Autor:
Gilles Gasparoni, Rosemarie Marchan, Heiko Hayen, Philipp Gabrys, Daniel Seehofer, Ahmed Ghallab, Thomas S. Weiss, Kathrin Gianmoena, Peter Boor, Katharina Grgas, Georg Damm, Tobias S. Schiergens, Eduardo Salido, Jörg Reinders, Patricio Godoy, Cristina Cadenas, Jörn Walter, Karolina Edlund, Clivia Lisowski, Nina Gasparoni, Alexander Schriewer, Karl Nordström, Christian A. Hudert, Philip Rosenstiel, Maren Falk-Paulsen, Jan G. Hengstler, Adelina Jashari, Manga Motrapu, Hans-Joachim Anders, Peter L.M. Jansen
Publikováno v:
Cell reports, 36(8):109526
Cell Reports, Vol 36, Iss 8, Pp 109526-(2021)
Cell Reports, 36(8):109526. Cell Press
Cell Reports, Vol 36, Iss 8, Pp 109526-(2021)
Cell Reports, 36(8):109526. Cell Press
Summary Epigenetic modifications (e.g. DNA methylation) in NAFLD and their contribution to disease progression and extrahepatic complications are poorly explored. Here, we use an integrated epigenome and transcriptome analysis of mouse NAFLD hepatocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f571b52cf8f5b02c6d64ba43ac054af0
https://www.sciencedirect.com/science/article/pii/S2211124721009578?via=ihub#app2
https://www.sciencedirect.com/science/article/pii/S2211124721009578?via=ihub#app2