Výsledky vyhledávání - "Nina Eggmann"

Autor: Sima Rozati, Jeannine D. Rinderknecht, Reinhard Dummer, Nina Eggmann, Simone M. Goldinger

Today, melanoma is considered as a spectrum of melanocytic malignancies that can be characterized by clinical and molecular features, including targetable mutations in several kinases. The successful development of therapies, targeting mutated BRaF (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ac5a90d78367f22847659b11fefac7
http://doc.rero.ch/record/297875/files/mds308.pdf

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Final results of a multicenter phase II study of the purine nucleoside phosphorylase (PNP) inhibitor forodesine in patients with advanced cutaneous t-cell lymphomas (CTCL) (Mycosis fungoides and Sézary syndrome)

Autor: Elise A. Olsen, J. Scarisbrick, Nina Eggmann, Sima Rozati, Youn H. Kim, K. Hutchinson, Simone M. Goldinger, E. Giuliano, M. Duvic, Larisa J. Geskin, Timothy M Illidge, Reinhard Dummer, J. Elder

Publikováno v: Annals of Oncology. 25:1807-1812

Background Forodesine is a potent inhibitor of purine nucleoside phosphorylase (PNP) that leads to intracellular accumulation of deoxyguanosine triphosphate (dGTP) in T and B cells, resulting in apoptosis. Forodesine has demonstrated impressive antit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694ba0d9b4e9882f722d3661155f0c5d
https://doi.org/10.1093/annonc/mdu231

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ILDS Newsletter No. 23

Autor: Stephan Schreml, Druck Reinhardt Druck Basel, Philipp Babilas, D. Gutkowicz-Krusin, Marjam J. Barysch, Jan Izakovic, E. Régnier-Rosencher, Kentaro Yonekura, Yoshihiro Sato, Oh Sang Kwon, Yuichi Teraki, Denis Salomon, Paolo Gisondi, Giampiero Girolomoni, Ji Won Lee, Kozo Hashimoto, A. Marghoob, Lucia Restano, C. Salliot, Robert J. Meier, Atae Utsunomiya, Rudolph Happle, Burkhardt Seifert, D. Farhi, Gianpaolo Tessari, A. Lebrun, I. Kolm, Satz Mengensatzproduktion, Lawrence A. Schachner, Renato G. Panizzon, Yuko Higashi, Soo Chan Kim, R. King, P. Googe, Eugénie Dalimier, A. Cognetta, M. Dougados, A.M. Skaria, Nina Eggmann, Wolfram Sterry, H. Rabinovitz, Michael Landthaler, Koichiro Takeda, Jean-Hilaire Saurat, L. French, Kazuhiro Kawai, Seunghee Lee, Daniela Zaharia, N. Dupin, Peter Itin, Takuro Kanekura, R.P. Braun, Raphael Battegay, Jean Kanitakis, Veronika Zeller, Hee Chul Eun, Tatsuya Nishioka, V.G. Prieto, Micol Del Giglio, V. Ahlgrimm-Siess, M. Mihm, Hans Christian Korting, Masayuki Shinohara, Tamotsu Kanzaki, Jwa-Seop Shin, Daniele Torchia, Christoph Itin, Barbara Behm, D. Polsky, Reinhard Dummer, Hyun Sun Yoon, Chizuru Kumagai, R. Hofmann-Wellenhof, Yuko Aso, Gianluca Tadini, Mirjam Beyeler, Noriyasu Tanimoto, M. Oliviero

Publikováno v: Dermatology. 224:93-96

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d1e62def8fa947430468c8bf84a1a69
https://doi.org/10.1159/000338702

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Vemurafenib in patients with BRAF(V600) mutation-positive melanoma with symptomatic brain metastases: final results of an open-label pilot study

Autor: L. Veronese, Reinhard Dummer, Simone M. Goldinger, Olivier Michielin, Christian P. Turtschi, Paul René Hilfiker, Lada Mitchell, Nina Eggmann, Lea Felderer, Jeannine D. Rinderknecht

Publikováno v: European journal of cancer (Oxford, England : 1990). 50(3)

Background & Aim Brain metastases are frequent in patients with metastatic melanoma, indicating poor prognosis. We investigated the BRAF kinase inhibitor vemurafenib in patients with advanced melanoma with symptomatic brain metastases. Methods This o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd44f368a4d5b9a157f44f10ec97e4c
https://pubmed.ncbi.nlm.nih.gov/24295639

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Long-term recurrence rate of large and difficult to treat cutaneous squamous cell carcinomas after superficial radiotherapy

Autor: Nina Eggmann, Renato G. Panizzon, Reinhard Dummer, Marjam J. Barysch, Burkhardt Seifert, Mirjam Beyeler

Publikováno v: Dermatology (Basel, Switzerland). 224(1)

Background: Surgical excision is the gold standard for cutaneous squamous cell carcinoma (cSCC), however its application is limited in specific cases. Superficial radiotherapy (RTx) is an alternative treatment option, but long-term follow-up data are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7145ef0649a4ceef5785cc67211512d1
https://pubmed.ncbi.nlm.nih.gov/22433440

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Open-Label Pilot Study of Vemurafenib in Previously Treated Metastatic Melanoma (MM) Patients (PTS) with Symptomatic Brain Metastases (BM)

Autor: Lada Mitchell, Nina Eggmann, Simone M. Goldinger, L. Veronese, R. Dummer, O. Michielin, Jeannine D. Rinderknecht, P.R. Hilfiker, C. Turtschi

Publikováno v: Annals of Oncology. 23:ix366

Background The BRAF inhibitor vemurafenib has shown high response rates and improved progression-free and overall survival in mM harbouring V600-mutated BRAF. BMs are often observed with mM and indicate a poor prognosis. The aim of this preliminary i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52ef5c75537603528ee9d7d1c49705d7
https://doi.org/10.1016/s0923-7534(20)33679-6

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Cutaneous side effects (cAE) of vemurafenib (V): Single-center cohort study of 28 metastatic melanoma (mM) patients (pts)

Autor: Benedetta Belloni, Nina Eggmann, Reinhard Dummer, Jeannine D. Rinderknecht, Simone M. Goldinger

Publikováno v: Journal of Clinical Oncology. 30:e19017-e19017

e19017 Background: V is a potent BRAF inhibitor with significant impact on progression-free and overall survival in mM pts. cAE are very common. This single-center observation analyses the clinical and histological spectrum of this new class-specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e59924bc581331c96c14f8fdff4e75b
https://doi.org/10.1200/jco.2012.30.15_suppl.e19017

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