Výsledky vyhledávání - "Nina Deppisch"

Akademický článek

Potential of the Trifunctional Bispecific Antibody Surek Depends on Dendritic Cells: Rationale for a New Approach of Tumor Immunotherapy

Autor: Nina Eissler, Josef Mysliwietz, Nina Deppisch, Peter Ruf, Horst Lindhofer, Ralph Mocikat

Publikováno v: Molecular Medicine, Vol 19, Iss 1, Pp 54-61 (2013)

Abstract Trifunctional bispecific antibodies (trAbs) used in tumor immunotherapy have the unique ability to recruit T cells toward antigens on the tumor cell surface and, moreover, to activate accessory cells through their immunoglobulin Fc region in

Externí odkaz: https://doaj.org/article/08ec4f4b1668430db55894883c0eab70

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Data from Efficacy and Tolerability of a GD2-Directed Trifunctional Bispecific Antibody in a Preclinical Model: Subcutaneous Administration Is Superior to Intravenous Delivery

Autor: Ralph Mocikat, Horst Lindhofer, Raymund Buhmann, Frauke Neff, Nina Eissler, Peter Ruf, Nina Deppisch

Trifunctional bispecific antibodies (trAb) are novel anticancer drugs that recruit and activate different types of immune effector cells at the targeted tumor. Thus, tumor cells are effectively eliminated and a long-lasting tumor-specific T-cell memo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251f0d06a62bf4124467a82046de7771
https://doi.org/10.1158/1535-7163.c.6538330.v1

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Supplementary Figures S1-S4 from Efficacy and Tolerability of a GD2-Directed Trifunctional Bispecific Antibody in a Preclinical Model: Subcutaneous Administration Is Superior to Intravenous Delivery

Autor: Ralph Mocikat, Horst Lindhofer, Raymund Buhmann, Frauke Neff, Nina Eissler, Peter Ruf, Nina Deppisch

Supplementary Figures S1-S4. Supplementary Figure S1. Development of anti-antibodies following Surek treatment; Supplementary Figure S2. Activation and proliferation of T cells after treatment with trAb Surek alone; Supplementary Figure S3. Weight lo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023d321dc26b367a9ecbc369a4022d5d
https://doi.org/10.1158/1535-7163.22506214

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Efficacy and Tolerability of a GD2-Directed Trifunctional Bispecific Antibody in a Preclinical Model: Subcutaneous Administration Is Superior to Intravenous Delivery

Autor: Nina Eissler, Ralph Mocikat, Raymund Buhmann, Horst Lindhofer, Peter Ruf, Frauke Neff, Nina Deppisch

Publikováno v: Molecular Cancer Therapeutics. 14:1877-1883

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea92677bbfc7bee193775cf3ca801c9
https://doi.org/10.1158/1535-7163.mct-15-0156

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Potential of the Trifunctional Bispecific Antibody Surek Depends on Dendritic Cells: Rationale for a New Approach of Tumor Immunotherapy

Autor: Josef Mysliwietz, Horst Lindhofer, Ralph Mocikat, Peter Ruf, Nina Deppisch, Nina Eissler

Publikováno v: Mol. Med. 19, 54-61 (2013)

Trifunctional bispecific antibodies (trAbs) used in tumor immunotherapy have the unique ability to recruit T cells toward antigens on the tumor cell surface and, moreover, to activate accessory cells through their immunoglobulin Fc region interacting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccfb238d729bb1556b6461bca215f2e
https://doi.org/10.2119/molmed.2012.00140

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Potent CD4+ T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition

Autor: Nina Eißler, Peter Ruf, Horst Lindhofer, Nina Deppisch, Ralph Mocikat

Publikováno v: Oncotarget
Oncotarget 8, 4520-4529 (2017)

// Nina Deppisch 1 , Peter Ruf 2 , Nina Eisler 1 , Horst Lindhofer 2 , Ralph Mocikat 1, 3 1 Institut fur Molekulare Immunologie, Helmholtz-Zentrum Munchen, Germany 2 Trion Research GmbH, Martinsried, Germany 3 AG Translationale Molekulare Immunologie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628cc857597013665278c7375a3f58de
https://pubmed.ncbi.nlm.nih.gov/27966460

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