Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nina D. Timberlake"'
Autor:
Krista A. Delviks-Frankenberry, Daniel Ackerman, Nina D. Timberlake, Maria Hamscher, Olga A. Nikolaitchik, Wei-Shau Hu, Bruce E. Torbett, Vinay K. Pathak
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 1023-1038 (2019)
Strategies to control HIV-1 replication without antiviral therapy are needed to achieve a functional cure. To exploit the innate antiviral function of restriction factor cytidine deaminase APOBEC3G (A3G), we developed self-activating lentiviral vecto
Externí odkaz:
https://doaj.org/article/8ce3c38bfdec4df3802934eb69e6970d
Autor:
Stosh Ozog, Craig X. Chen, Elizabeth Simpson, Olivia Garijo, Nina D. Timberlake, Petra Minder, Els Verhoeyen, Bruce E. Torbett
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 27-39 (2019)
Lentiviral vectors (LVs) pseudotyped with the measles virus hemagglutinin (H) and fusion (F) glycoproteins have been reported to more efficiently transduce hematopoietic stem and progenitor cells (HSPCs) compared with vesicular stomatitis virus glyco
Externí odkaz:
https://doaj.org/article/fddd9b144ec5464e8213e1eb8573ad39
Autor:
Daniel Ackerman, Vinay K. Pathak, Wei-Shau Hu, Olga A. Nikolaitchik, Krista A. Delviks-Frankenberry, Maria Hamscher, Bruce E. Torbett, Nina D. Timberlake
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss, Pp 1023-1038 (2019)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Strategies to control HIV-1 replication without antiviral therapy are needed to achieve a functional cure. To exploit the innate antiviral function of restriction factor cytidine deaminase APOBEC3G (A3G), we developed self-activating lentiviral vecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6445ceec1b06f144035b1b2c2c3da035
http://www.sciencedirect.com/science/article/pii/S2162253119303348
http://www.sciencedirect.com/science/article/pii/S2162253119303348
Autor:
Olivia Garijo, Bruce E. Torbett, Elizabeth Simpson, Petra Minder, Craig X. Chen, Stosh Ozog, Els Verhoeyen, Nina D. Timberlake
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 27-39 (2019)
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 27-39 (2019)
Lentiviral vectors (LVs) pseudotyped with the measles virus hemagglutinin (H) and fusion (F) glycoproteins have been reported to more efficiently transduce hematopoietic stem and progenitor cells (HSPCs) compared with vesicular stomatitis virus glyco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946d96af4c68480d60be200667333678
http://europepmc.org/articles/PMC6310745
http://europepmc.org/articles/PMC6310745
Autor:
Dale L. Boger, Gabriella Sghia-Hughes, Christopher M. Glinkerman, Elizabeth Simpson, Guoli Shi, Raymond R. Carillo, Saritha S. D'Souza, Kip Hermann, Hans-Peter Kiem, Nina D. Timberlake, Scott A. Snyder, Lauren E Schefter, Jennifer E. Adair, Kevin G. Haworth, Byoung Y. Ryu, Brian P. Sorrentino, Olivia Garijo, Bruce E. Torbett, Igor I. Slukvin, Stosh Ozog, Alex A. Compton
Publikováno v:
Blood
Therapeutic gene delivery to hematopoietic stem cells (HSCs) holds great potential as a life-saving treatment of monogenic, oncologic, and infectious diseases. However, clinical gene therapy is severely limited by intrinsic HSC resistance to modifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe627ca95d25d774eed5e2965968dee
https://pubmed.ncbi.nlm.nih.gov/31416800
https://pubmed.ncbi.nlm.nih.gov/31416800
Autor:
Scott A. Snyder, Saritha S. D'Souza, Nina D. Timberlake, Sergio D. Catz, Igor I. Slukvin, Bruce E. Torbett, Stosh Ozog
Publikováno v:
Molecular Therapy. 24:S2-S3
A major obstacle to the success of gene therapy for hematologic disorders is the inefficiency of lentiviral vector (LV) gene transfer to hematopoietic stem cells (HSCs). Achieving clinically relevant gene delivery levels requires prolonged ex vivo cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a3c07f0e86a4fd94ed302b1b382d411
https://doi.org/10.1016/s1525-0016(16)32813-1
https://doi.org/10.1016/s1525-0016(16)32813-1