Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Nina C Weber"'
Autor:
Jan Fraessdorf, Markus W Hollmann, Iris Hanschmann, André Heinen, Nina C Weber, Benedikt Preckel, Ragnar Huhn
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134283 (2015)
Opioid receptors (OR) are involved in myocardial late preconditioning (LPC) induced by morphine and δ1-opioid receptor (δ1-OR) agonists. The role of OR in ischemic-induced LPC is unknown. We investigated whether 1) OR are involved in the trigger an
Externí odkaz:
https://doaj.org/article/14f07c05db624dc7a5bcfef7d770ddce
Autor:
Christian Fastner, Heimo Mairbäurl, Nina C Weber, Koen van der Sluijs, Florian Hackl, Lorenz Hotz, Albert Dahan, Markus W Hollmann, Marc M Berger
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112622 (2014)
We previously demonstrated that intratracheally administered S-ketamine inhibits alveolar fluid clearance (AFC), whereas an intravenous (i.v.) bolus injection had no effect. The aim of the present study was to characterize whether continuous i.v. inf
Externí odkaz:
https://doaj.org/article/ef58b3630684447c9814e7482dfd0458
Autor:
Hamid Aslami, Wilco P Pulskens, Maria T Kuipers, Aafkeline P Bos, André B P van Kuilenburg, Ronald J A Wanders, Jeroen Roelofsen, Joris J T H Roelofs, Raphaela P Kerindongo, Charlotte J P Beurskens, Marcus J Schultz, Wim Kulik, Nina C Weber, Nicole P Juffermans
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63497 (2013)
Sepsis is characterized by a generalized inflammatory response and organ failure, associated with mitochondrial dysfunction. Hydrogen sulfide donor NaHS has anti-inflammatory properties, is able to reduce metabolism and can preserve mitochondrial mor
Externí odkaz:
https://doaj.org/article/66d0b4d10b034ee9a477c87e096ffef5
Autor:
Sha Chen, Kenneth Overberg, Zakiya Ghouse, Markus W. Hollmann, Nina C. Weber, Ruben Coronel, Coert J. Zuurbier
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116477- (2024)
Background: SGLT2i reduce cardiac hypertrophy, but underlying mechanisms remain unknown. Here we explore a role for serine/threonine kinases (STK) and sodium hydrogen exchanger 1(NHE1) activities in SGLT2i effects on cardiac hypertrophy. Methods: Iso
Externí odkaz:
https://doaj.org/article/66c45ad5380a457c848948bdb50a2688
Autor:
Daan P. van den Brink, Derek J. B. Kleinveld, Annabel Bongers, Jaël Vos, Joris J. T. H. Roelofs, Nina C. Weber, Jaap D. van Buul, Nicole P. Juffermans
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Background Endothelial injury and permeability are a hallmark of sepsis. Initial resuscitation of septic patients with crystalloids is associated with aggravation of endothelial permeability, which may be related either to low protein conten
Externí odkaz:
https://doaj.org/article/2e71c8bb73db4b7498d7cd7a174e6bfb
Autor:
Raoul A. Fakkert, Noa Karlas, Patrick Schober, Nina C. Weber, Benedikt Preckel, Robert A. van Hulst, Robert P. Weenink
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-7 (2023)
Abstract Background Iatrogenic cerebral arterial gas embolism (CAGE) caused by invasive medical procedures may be treated with hyperbaric oxygen therapy (HBOT). Previous studies suggested that initiation of HBOT within 6–8 h is associated with high
Externí odkaz:
https://doaj.org/article/792c03fd9cc941198ee3c9afbf864ae0
Autor:
Xiaoling Li, Mengnan Wang, Jan-Ole Kalina, Benedikt Preckel, Markus W. Hollmann, Martin Albrecht, Coert J. Zuurbier, Nina C. Weber
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 102979- (2024)
Background: Empagliflozin (EMPA) ameliorates reactive oxygen species (ROS) generation in human endothelial cells (ECs) exposed to 10 % stretch, but the underlying mechanisms are still unclear. Pathological stretch is supposed to stimulate protein kin
Externí odkaz:
https://doaj.org/article/2f33de2efafb4ef0b4548402cf79295b
Autor:
Xiaoling Li, Raphaela P. Kerindongo, Benedikt Preckel, Jan-Ole Kalina, Markus W. Hollmann, Coert J. Zuurbier, Nina C. Weber
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114228- (2023)
Background: Canagliflozin (CANA) shows anti-inflammatory and anti-oxidative effects on endothelial cells (ECs). In diabetes mellitus (DM), excessive reactive oxygen species (ROS) generation, increased intracellular calcium (Ca2+) and enhanced extrace
Externí odkaz:
https://doaj.org/article/d73cc82c10a8419f99317442d2fbd5da
Autor:
Qian Wang, Coert J. Zuurbier, Ragnar Huhn, Carolin Torregroza, Markus W. Hollmann, Benedikt Preckel, Charissa E. van den Brom, Nina C. Weber
Publikováno v:
Cells, Vol 12, Iss 10, p 1432 (2023)
Pharmacological conditioning aims to protect the heart from myocardial ischemia-reperfusion injury (IRI). Despite extensive research in this area, today, a significant gap remains between experimental findings and clinical practice. This review provi
Externí odkaz:
https://doaj.org/article/7c2f903cb2d14ff5aa142cd8e9b5eddb
Autor:
Laween Uthman, Xiaoling Li, Antonius Baartscheer, Cees A. Schumacher, Patricia Baumgart, Jeroen Hermanides, Benedikt Preckel, Markus W. Hollmann, Ruben Coronel, Coert J. Zuurbier, Nina C. Weber
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112515- (2022)
Inflammation causing oxidative stress in endothelial cells contributes to heart failure development. Sodium/glucose cotransporter 2 inhibitors (SGLT2i’s) were shown to reduce heart failure hospitalization and oxidative stress. However, how inflamma
Externí odkaz:
https://doaj.org/article/714ef2cb2d7f40598704c5380f100e1b