Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nina Braun"'
Autor:
Cameron L. Noland, Han Chow Chua, Marc Kschonsak, Stephanie Andrea Heusser, Nina Braun, Timothy Chang, Christine Tam, Jia Tang, Christopher P. Arthur, Claudio Ciferri, Stephan Alexander Pless, Jian Payandeh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
NaX is an atypical member of the voltage-gated sodium channel family that may contribute to Na+ homeostasis. Here, the authors describe the structural and functional attributes of the human NaX channel to reveal new insights into its physiology.
Externí odkaz:
https://doaj.org/article/2f977168e29d4738843b01d6e6b08fea
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001321 (2021)
Incorporation of noncanonical amino acids (ncAAs) can endow proteins with novel functionalities, such as crosslinking or fluorescence. In ion channels, the function of these variants can be studied with great precision using standard electrophysiolog
Externí odkaz:
https://doaj.org/article/be6c4a9da5ab4067909c632cb3b953e3
Publikováno v:
Swiss Medical Weekly, Vol 145, Iss 5152 (2015)
Although obesity and the associated metabolic syndrome negatively impact on health outcomes, a paradoxical relationship between obesity and mortality has been reported for specific patient populations – the “obesity paradox”. However, underlyin
Externí odkaz:
https://doaj.org/article/735262dcb1be41b794c43a8fbd59e647
Publikováno v:
Brain Structure & Function
The ventrolateral thalamic nucleus (VL), as part of the ‘motor thalamus’, is main relay station of cerebellar and pallidal projections. It comprises anterior (VLa) and posterior (VLpd and VLpv) subnuclei. Though the fibre architecture of cerebell
Autor:
Michael Hauser, Sabrina Wildner, Stefanie Wagner, Gerlinde Hofstetter, Nina Braun, Erika Jensen-Jarolim, Gabriele Gadermaier, Karin Hufnagl, Franziska Roth-Walter, Bart R. Blokhuis, Frank A. Redegeld, Sheriene Moussa Afify, Michael Wallner, Isabella Pali-Schöll, Luis F. Pacios, Markus Wiederstein
Publikováno v:
Allergy. 75:2073-2077
Publikováno v:
Energy and Sun ISBN: 9783868598780
Energy and Sun
Energy and Sun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62560ab93fccb86341ad5daaf4b39b85
https://doi.org/10.1515/9783868598780-017
https://doi.org/10.1515/9783868598780-017
Autor:
Cameron L, Noland, Han Chow, Chua, Marc, Kschonsak, Stephanie Andrea, Heusser, Nina, Braun, Timothy, Chang, Christine, Tam, Jia, Tang, Christopher P, Arthur, Claudio, Ciferri, Stephan Alexander, Pless, Jian, Payandeh
Publikováno v:
Nature communications. 13(1)
Unlike classical voltage-gated sodium (Na
Autor:
Søren Friis, Laura Hutchison, Paola Madau, Stephan A. Pless, Davide Pau, Alison Obergrussberger, Nadine Becker, Maria Giustina Rotordam, Markus Rapedius, David Dalrymple, Niels Fertig, Nina Braun, Ilka Rinke-Weiß, Tom A. Goetze, Nina Brinkwirth
Publikováno v:
Obergrussberger, A, Rinke-Weiß, I, Goetze, T A, Rapedius, M, Brinkwirth, N, Becker, N, Rotordam, M G, Hutchison, L, Madau, P, Pau, D, Dalrymple, D, Braun, N, Friis, S, Pless, S A & Fertig, N 2022, ' The suitability of high throughput automated patch clamp for physiological applications ', Journal of Physiology, vol. 600, no. 2, pp. 277-297 . https://doi.org/10.1113/JP282107
Although automated patch clamp (APC) devices have been around for many years and have become an integral part of many aspects of drug discovery, high throughput instruments with gigaohm seal data quality are relatively new. Experiments where a large
Publikováno v:
Braun, N, Friis, S, Ihling, C, Sinz, A, Andersen, J & Pless, S A 2021, ' High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology ', PLOS Biology, vol. 19, no. 9, e3001321 . https://doi.org/10.1371/journal.pbio.3001321
PLoS Biology, Vol 19, Iss 9, p e3001321 (2021)
PLoS Biology
PLoS Biology, Vol 19, Iss 9, p e3001321 (2021)
PLoS Biology
Incorporation of noncanonical amino acids (ncAAs) can endow proteins with novel functionalities, such as crosslinking or fluorescence. In ion channels, the function of these variants can be studied with great precision using standard electrophysiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47ac6c5162cc821f06ca74915038c50
https://doi.org/10.1101/2020.11.24.392498
https://doi.org/10.1101/2020.11.24.392498
Publikováno v:
The Journal of physiologyReferences. 598(20)
Ion channels play important roles in human physiology and their dysfunction is linked to a variety of diseases. This has sparked considerable interest in their molecular function and pharmacology and generated a need to manipulate them with great pre