Efficient and unique cobarcoding of second-generation sequencing reads from long DNA molecules enabling cost-effective and accurate sequencing, haplotyping, and de novo assembly

Autor: Xiao Liu, Rebecca Yu Zhang, Yan Zou, Chongjun Xu, Nina Barua, Ou Wang, Han K. Lam, Xun Xu, Jingbo Tang, Yujun Zhou, Jing Wang, Yinlong Xie, Xiaofang Cheng, Brock A. Peters, Wenlan Tian, Jingwan Wang, Fei Fan, Dan Chen, Jia Sophie Liu, Ao Chen, Snezana Drmanac, Andrei Alexeev, Yuhui Sun, Linying Wang, Radoje Drmanac, Ellis Anderson, Xiaojuan Qi, Dong Yuliang, Wenwei Zhang, M. Wu, Robert Chin, Huanming Yang, Qing Mao, Christian Villarosa, Karsten Kristiansen, Staci Nguyen, Scott Gablenz, He Wang, Darlene Nguyen

Publikováno v: Wang, O, Chin, R, Cheng, X, Wu, M K Y, Mao, Q, Tang, J, Sun, Y, Anderson, E, Lam, H K, Chen, D, Zhou, Y, Wang, L, Fan, F, Zou, Y, Xie, Y, Zhang, R Y, Drmanac, S, Nguyen, D, Xu, C, Villarosa, C, Gablenz, S, Barua, N, Nguyen, S, Tian, W, Liu, J S, Wang, J, Liu, X, Qi, X, Chen, A, Wang, H, Dong, Y, Zhang, W, Alexeev, A, Yang, H, Wang, J, Kristiansen, K, Xu, X, Drmanac, R & Peters, B A 2019, ' Efficient and unique cobarcoding of second-generation sequencing reads from long DNA molecules enabling cost-effective and accurate sequencing, haplotyping, and de novo assembly ', Genome Research, vol. 29, no. 5, pp. 798-808 . https://doi.org/10.1101/gr.245126.118

Here, we describe single-tube long fragment read (stLFR), a technology that enables sequencing of data from long DNA molecules using economical second-generation sequencing technology. It is based on adding the same barcode sequence to subfragments o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6de987fdf799d1cbdb17c1b96eee50
https://curis.ku.dk/portal/da/publications/efficient-and-unique-cobarcoding-of-secondgeneration-sequencing-reads-from-long-dna-molecules-enabling-costeffective-and-accurate-sequencing-haplotyping-and-de-novo-assembly(17bcf649-f5eb-48d0-b4a6-5250b87c3764).html

Clinical and genetic analysis of a rare syndrome associated with neoteny

Autor: Serban Ciotlos, Rebecca Yu Zhang, Radoje Drmanac, Misha R. Agarwal, Brock A. Peters, Richard F. Walker, Staci Nguyen, Qing Mao, Robert Chin, Zhenyu Li, Paolo Carnevali, M. Wu, Snezana Drmanac, Jia Sophie Liu, Kevin Sun, Nina Barua, Katharine Lee

Publikováno v: Genetics in medicine : official journal of the American College of Medical Genetics. 20(5)

PurposeWe describe a novel syndrome in seven female patients with extreme developmental delay and neoteny.MethodsAll patients in this study were female, aged 4 to 23 years, were well below the fifth percentile in height and weight, had failed to deve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4a7028d881bc2a89401401b9ec7af2
https://pubmed.ncbi.nlm.nih.gov/29758565