Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Nina A. Bonekamp"'
Autor:
Stephen P. Burr, Florian Klimm, Angelos Glynos, Malwina Prater, Pamella Sendon, Pavel Nash, Christopher A. Powell, Marie-Lune Simard, Nina A. Bonekamp, Julia Charl, Hector Diaz, Lyuba V. Bozhilova, Yu Nie, Haixin Zhang, Michele Frison, Maria Falkenberg, Nick Jones, Michal Minczuk, James B. Stewart, Patrick F. Chinnery
Publikováno v:
Cell
1229.E21
1229.E21
Mitochondrial activity differs markedly between organs, but it is not known how and when this arises. Here we show that cell lineage-specific expression profiles involving essential mitochondrial genes emerge at an early stage in mouse development, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f0cb0645b86f5d93340ecb65896a8a
Autor:
Tina A. Schrader, Ruth E. Carmichael, Markus Islinger, Joseph L. Costello, Christian Hacker, Nina A. Bonekamp, Jochen H. Weishaupt, Peter M. Andersen, Michael Schrader
Publikováno v:
Journal of cell science. 135(13)
Peroxisome membrane dynamics and division are essential to adapt the peroxisomal compartment to cellular needs. The peroxisomal membrane protein PEX11β (also known as PEX11B) and the tail-anchored adaptor proteins FIS1 (mitochondrial fission protein
Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR-Cas9 screen
Autor:
Patrick Giavalisco, Oleksandr Lytovchenko, Roberta Filograna, Andrea Felser, Mara Mennuni, Nina A Bonekamp, Nils-Göran Larsson
Publikováno v:
EMBO Rep
EMBO Reports
EMBO Reports
Cancer cells depend on mitochondria to sustain their increased metabolic need and mitochondria therefore constitute possible targets for cancer treatment. We recently developed small‐molecule inhibitors of mitochondrial transcription (IMTs) that se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6b104519b6542bbe7542a948241955
https://hdl.handle.net/21.11116/0000-000B-B6C6-8
https://hdl.handle.net/21.11116/0000-000B-B6C6-8
Autor:
Nina A. Bonekamp, Rodolfo Garcia Villegas, Ilian Atanassov, Camilla Koolmeister, Nils-Göran Larsson, Elisa Motori, Chan Bae Park, Andrea Mesaros, Min Jiang
Publikováno v:
Life Sci Alliance
Life Science Alliance
Life Science Alliance
The TFAM-to-mtDNA ratio is critically important and must be maintained within a physiological range to allow normal mtDNA expression and prevent nucleoid hypercompaction in different mouse tissues.
Mitochondrial transcription factor A (TFAM) is
Mitochondrial transcription factor A (TFAM) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad6c9471ca7486d2a0d737ed876c16f
https://hdl.handle.net/21.11116/0000-000A-FABB-A
https://hdl.handle.net/21.11116/0000-000A-FABB-A
Autor:
Nina A Bonekamp, Sandra Grille, Maria Joao Cardoso, Monica Almeida, Miguel Aroso, Silvia Gomes, Ana Cristina Magalhaes, Daniela Ribeiro, Markus Islinger, Michael Schrader
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53424 (2013)
Pex11 proteins are involved in membrane elongation and division processes associated with the multiplication of peroxisomes. Human Pex11pβ has recently been linked to a new disorder affecting peroxisome morphology and dynamics. Here, we have analyze
Externí odkaz:
https://doaj.org/article/1d312833ac8346b3aa2ffa78f518cd43
Autor:
Nina A. Bonekamp, Nils-Göran Larsson
Publikováno v:
Cell
Mitochondrial DNA is compacted into nucleoprotein complexes denoted mitochondrial nucleoids, the focus of this SnapShot.
Autor:
Nils-Göran Larsson, Arnaud Mourier, James B. Stewart, Marita A Isokallio, Alexandra Just, Nina A. Bonekamp, Timo E.S. Kauppila, Johanna H.K. Kauppila
Publikováno v:
Nucleic Acids Res
Nucleic Acids Research
Nucleic Acids Research
Mitochondrial DNA (mtDNA) mutations become more prevalent with age and are postulated to contribute to the ageing process. Point mutations of mtDNA have been suggested to originate from two main sources, i.e. replicative errors and oxidative damage,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c573661e5b5b4505a9cbc7e6f5147f1
https://hdl.handle.net/21.11116/0000-0004-720F-C
https://hdl.handle.net/21.11116/0000-0004-720F-C
Autor:
Nils-Göran Larsson, Stefan Jakobs, Paola Loguercio Polosa, Inge Kühl, Christian A. Wurm, Nina A. Bonekamp, Friederike Joos, Maria Falkenberg, Christian Kukat, Henrik Spåhr, Chan Bae Park, Viktor Posse, Karen M. Davies, Werner Kühlbrandt
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Mammalian mitochondrial DNA (mtDNA) is packaged by mitochondrial transcription factor A (TFAM) into mitochondrial nucleoids that are of key importance in controlling the transmission and expression of mtDNA. Nucleoid ultrastructure is poorly defined,
Autor:
Joseph L, Costello, Inês G, Castro, Fátima, Camões, Tina A, Schrader, Doug, McNeall, Jing, Yang, Evdokia-Anastasia, Giannopoulou, Sílvia, Gomes, Vivian, Pogenberg, Nina A, Bonekamp, Daniela, Ribeiro, Matthias, Wilmanns, Gregory, Jedd, Markus, Islinger, Michael, Schrader
Publikováno v:
Journal of Cell Science
Tail-anchored (TA) proteins contain a single transmembrane domain (TMD) at the C-terminus that anchors them to the membranes of organelles where they mediate critical cellular processes. Accordingly, mutations in genes encoding TA proteins have been
Autor:
Michael Schrader, Nina A. Bonekamp
Publikováno v:
Communicative & Integrative Biology. 5:534-537
Mitochondria and peroxisomes are ubiquitous subcellular organelles that fulfill essential metabolic functions, rendering them indispensable for human development and health. Both are highly dynamic organelles that can undergo remarkable changes in mo