Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nina, Ljumanovic"'
Autor:
Victor Yip, Shuguang Ma, M. Violet Lee, S. Cyrus Khojasteh, Amrita V. Kamath, Hao Cai, Nina Ljumanovic, Sylvia C. Wong, Ola Saad, Ben-Quan Shen
Publikováno v:
Drug Metabolism and Disposition. 48:1161-1168
Invasive Staphylococcus aureus infection is a leading cause of infectious disease-related deaths because S. aureus survives within host phagocytic cells, from which the bacteria are not adequately eliminated using current antibiotic treatments. Anti-
Autor:
Domagoj Vucic, Jonathan Maher, Tatiana Goncharov, Hua Zhang, Nina Ljumanovic, Brent S. McKenzie, Joshua D. Webster, Nick Corr, Youngsu Kwon, Sara F Santagostino, Summer Park, Snahel Patel, Eugene Varfolomeev, Jessica Preston, Adeyemi O Adedeji, Min Xu
Publikováno v:
Journal of Leukocyte Biology
Receptor interacting protein kinase 1 (RIP1) is a critical effector of inflammatory responses and cell death activation. Cell death pathways regulated by RIP1 include caspase‐dependent apoptosis and caspase‐independent necroptosis. The kinase act
Publikováno v:
Toxicology and applied pharmacology. 418
Tumor progression locus 2 (Tpl2, gene name MAP3K8), a mitogen-activated protein kinase, is widely expressed in immune and non-immune cells to integrate tumor necrosis factor (TNF), toll-like receptors (TLRs), and interleukin-1 (IL1) receptor signalin
Autor:
Hao, Cai, Victor, Yip, M Violet, Lee, Sylvia, Wong, Ola, Saad, Shuguang, Ma, Nina, Ljumanovic, S Cyrus, Khojasteh, Amrita V, Kamath, Ben-Quan, Shen
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 48(11)
Invasive
Autor:
Nicola J, Stagg, Paula, Katavolos, Kirsten, Achilles Poon, Shelly, Zhong, Nina, Ljumanovic, Amrita, Kamath, Hao, Cai, Montserrat, Carrasco-Triguero, Wendy, Halpern
Publikováno v:
Toxicology and Applied Pharmacology. 435:115811
Invasive Staphylococcus aureus (S. aureus) infections are a leading cause of death and not effectively treated with prolonged standard of care antibiotics. A novel THIOMAB™ antibody antibiotic conjugate (TAC) was developed that uses a bacterial-wal
Autor:
Ola Saad, Jason B Dinoso, Carrie M. Rosenberger, Sanjeev Mariathasan, Chenguang Zhou, Johnny Gutierrez, Kyu Hong, Montserrat Carrasco-Triguero, Neelima Koppada, Amos Baruch, Nina Ljumanovic, Amrita V. Kamath, Sophie M. Lehar
Publikováno v:
mAbs
DSTA4637A, a novel THIOMAB™ antibody antibiotic conjugate (TAC) against Staphylococcus aureus (S. aureus), is currently being investigated as a potential therapy against S. aureus infections. Structurally, TAC is composed of an anti-S. aureus antib
Autor:
C. Andrew Boswell, Kedan Lin, Paul Polakis, Crystal Zhang, Ron Firestein, Herman Gill, Shannon Stainton, Eduardo E. Mundo, Sheila Ulufatu, Leslie A. Khawli, Nina Ljumanovic, Reina N. Fuji, Cynthia Young, Aimee Fourie, Katherine R. Kozak, Weiguang Mao
Publikováno v:
British Journal of Pharmacology. 168:445-457
Background and Purpose The success of antibody-drug conjugates (ADCs) depends on the therapeutic window rendered by the differential expression between normal and pathological tissues. The ability to identify and visualize target expression in normal