Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nina, Karamanova"'
Autor:
Yining Zhang, Nina Karamanova, Kaleb T. Morrow, Jillian Madine, Seth Truran, Maria Lozoya, Volkmar Weissig, Ming Li, Mehdi Nikkhah, Jin G. Park, Raymond Q. Migrino
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Medin is a common vascular amyloidogenic peptide recently implicated in Alzheimer’s disease (AD) and vascular dementia and its pathology remains unknown. We aim to identify changes in transcriptomic profiles and pathways in human brain mic
Externí odkaz:
https://doaj.org/article/7d468b4c371e4ade9f15a6a89eb164c8
Autor:
Raymond Q. Migrino, Nina Karamanova, Seth Truran, Geidy E. Serrano, Hannah A. Davies, Jillian Madine, Thomas G. Beach
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Medin, an aging‐associated amyloidogenic protein, induces cerebrovascular dysfunction and inflammation. We investigated the relationship between cerebrovascular medin and Alzheimer's disease (AD) and vascular dementia (VaD). M
Externí odkaz:
https://doaj.org/article/4298e3d248cb4c78a5b46905644e680e
Autor:
Nina Karamanova, Seth Truran, Geidy E. Serrano, Thomas G. Beach, Jillian Madine, Volkmar Weissig, Hannah A. Davies, Jaimeson Veldhuizen, Mehdi Nikkhah, Michael Hansen, Weiyang Zhang, Karen D'Souza, Daniel A. Franco, Raymond Q. Migrino
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 2 (2020)
Background The function of medin, one of the most common human amyloid proteins that accumulates in the vasculature with aging, remains unknown. We aim to probe medin's role in cerebrovascular disease by comparing cerebral arterial medin content betw
Externí odkaz:
https://doaj.org/article/d05c9fe4b849467391c481a6df8d9070
Autor:
Daniel R, Griffiths, L Matthew, Law, Conor, Young, Alberto, Fuentes, Seth, Truran, Nina, Karamanova, Laura C, Bell, Gregory, Turner, Hannah, Emerson, Diego, Mastroeni, Rayna J, Gonzales, Peter D, Reaven, C Chad, Quarles, Raymond Q, Migrino, Jonathan, Lifshitz
Publikováno v:
Journal of Neurotrauma. 39:1429-1441
Severe traumatic brain injury (TBI) results in cognitive dysfunction in part due to vascular perturbations. In contrast, the long-term vasculo-cognitive pathophysiology of mild TBI (mTBI) remains unknown. We evaluated mTBI effects on chronic cognitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a453e54de76690a2e16c74de43cb52
https://doi.org/10.1089/neu.2022.0015
https://doi.org/10.1089/neu.2022.0015
Autor:
Natalie L Nabaty, Nina Karamanova, Seth Truran, Kaleb Morrow, Robert Schafer, Mehdi Nikkhah, Ming Li, Jillian Madine, Raymond Q Migrino
Publikováno v:
Stroke. 54
Background: Vascular aging is characterized by endothelial dysfunction and proinflammatory & prothrombotic changes. It is responsible for aging-associated pathologies including stroke, vascular dementia (VaD) and Alzheimer’s disease (AD). The under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78066c3c3599458e5e6e7dbbcf18c52e
https://doi.org/10.1161/str.54.suppl_1.tp222
https://doi.org/10.1161/str.54.suppl_1.tp222
Autor:
Jaimeson Veldhuizen, Helen F. Mann, Nina Karamanova, Wade D. Van Horn, Raymond Q. Migrino, David Brafman, Mehdi Nikkhah
Publikováno v:
Science Advances. 8
Long QT syndrome (LQTS) is a cardiovascular disease characterized by QT interval prolongation that can lead to sudden cardiac death. Many mutations with heterogeneous mechanisms have been identified in KCNH2 , the gene that encodes for hERG (Kv11.1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e02f52fc83261a5b369719ceff5409a
https://doi.org/10.1126/sciadv.abq6720
https://doi.org/10.1126/sciadv.abq6720
Autor:
Daniel A. Franco, Seth Truran, Volkmar Weissig, Diana Guzman‐Villanueva, Nina Karamanova, Subhadip Senapati, Camelia Burciu, Marina Ramirez‐Alvarado, Luis M. Blancas‐Mejia, Stuart Lindsay, Parameswaran Hari, Raymond Q. Migrino
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 6 (2016)
BackgroundLight chain amyloidosis (AL) is associated with high mortality, especially in patients with advanced cardiovascular involvement. It is caused by toxicity of misfolded light chain proteins (LC) in vascular, cardiac, and other tissues. There
Externí odkaz:
https://doaj.org/article/4ccb7dc4ecb14d59b564340d43dae37b
Autor:
Nina Karamanova, Andrew F. Ducruet, Raymond Q. Migrino, Seth Truran, Volkmar Weissig, Maria Lozoya, Hannah Emerson, Saif Ahmad, Daniel R. Griffiths, Tyler Vail, Adam Kindelin, Jonathan Lifshitz
Publikováno v:
Stroke. 53
Background and Purpose: Neuroprotective strategies for stroke remain inadequate. Nanoliposomes comprised of phosphatidylcholine, cholesterol, and monosialogangliosides (nanoliposomes) induced an antioxidant protective response in endothelial cells ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987e7f597dc77c52e85139acbdf8f8ca
https://doi.org/10.1161/strokeaha.121.037120
https://doi.org/10.1161/strokeaha.121.037120
Autor:
Daniel R. Griffiths, L. Matthew Law, Conor Young, Alberto Fuentes, Seth Truran, Nina Karamanova, Laura C. Bell, Gregory Turner, Hannah Emerson, Diego Mastroeni, Rayna Gonzales, Peter D. Reaven, Chad C. Quarles, Raymond Q. Migrino, Jonathan Lifshitz
Severe traumatic brain injury results in cognitive dysfunction in part due to vascular perturbations. In contrast, the long-term vasculo-cognitive pathophysiology of mild TBI (mTBI) remains unknown. We evaluated mTBI effects on chronic cognitive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::484ef74cf87787b48c9fa9239f58e2c1
https://doi.org/10.1101/2022.01.05.474992
https://doi.org/10.1101/2022.01.05.474992
Publikováno v:
Circulation. 144
Background: Vascular aging is characterized by acquisition of a pro-inflammatory and prothrombotic vascular phenotype independent of cardiovascular metabolic risk factors through still unknown mechanisms. Medin is an amyloidogenic peptide formed as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5720cb1cb22d71772dbfdd22a8c4eca9
https://doi.org/10.1161/circ.144.suppl_1.11596
https://doi.org/10.1161/circ.144.suppl_1.11596