Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nimrod, Miller"'
Autor:
Éanna B. Ryan, Jianhua Yan, Nimrod Miller, Sudarshan Dayanidhi, Yongchao C. Ma, Han-Xiang Deng, Teepu Siddique
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102061- (2021)
Summary: Mutations in coiled-coil-helix-coiled-coil-helix domain containing 10 (CHCHD10) have been identified in patients suffering from various degenerative diseases including mitochondrial myopathy, spinal muscular atrophy Jokela type, frontotempor
Externí odkaz:
https://doaj.org/article/33aca3422669407a9e11c79ae56d769e
Publikováno v:
eLife, Vol 6 (2017)
The etiological underpinnings of amyotrophic lateral sclerosis (ALS) are complex and incompletely understood, although contributions to pathogenesis by regulators of proteolytic pathways have become increasingly apparent. Here, we present a novel var
Externí odkaz:
https://doaj.org/article/d56a80c9cd784894b56a22723e6abfe1
Autor:
Hailing Shi, Nimrod Miller, Allen Zhu, Yong Chao Ma, Zhike Lu, Brittany M. Edens, Chuan He, Phillip J. Hsu
Publikováno v:
Journal of Biological Chemistry. 294:19889-19895
N6-Methyladenosine (m6A) is the most abundant post-transcriptional mRNA modification in eukaryotes and exerts many of its effects on gene expression through reader proteins that bind specifically to m6A-containing transcripts. Fragile X mental retard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::965219dfb88e415208153c7091fb3bcd
https://doi.org/10.1074/jbc.ac119.010078
https://doi.org/10.1074/jbc.ac119.010078
Autor:
Jesse M Gray, David A Harmin, Sarah A Boswell, Nicole Cloonan, Thomas E Mullen, Joseph J Ling, Nimrod Miller, Scott Kuersten, Yong-Chao Ma, Steven A McCarroll, Sean M Grimmond, Michael Springer
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89673 (2014)
mRNA synthesis, processing, and destruction involve a complex series of molecular steps that are incompletely understood. Because the RNA intermediates in each of these steps have finite lifetimes, extensive mechanistic and dynamical information is e
Externí odkaz:
https://doaj.org/article/1a3d01b1100d44b6a39d16e65f33d481
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45241 (2012)
Aplysia feeding is a model system for examining the neural mechanisms by which changes in motivational state control behavior. When food is intermittently present, Aplysia eat large meals controlled by a balance between food stimuli exciting feeding
Externí odkaz:
https://doaj.org/article/e1d2bd9012734aae80b7418beb2d7f04
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17779 (2011)
Neural activity can be affected by nitric oxide (NO) produced by spiking neurons. Can neural activity also be affected by NO produced in neurons in the absence of spiking?Applying an NO scavenger to quiescent Aplysia buccal ganglia initiated fictive
Externí odkaz:
https://doaj.org/article/10219c2c341742d88554fb219f75ed10
Autor:
Phillip J, Hsu, Hailing, Shi, Allen C, Zhu, Zhike, Lu, Nimrod, Miller, Brittany M, Edens, Yongchao C, Ma, Chuan, He
Publikováno v:
J Biol Chem
N(6)-Methyladenosine (m(6)A) is the most abundant post-transcriptional mRNA modification in eukaryotes and exerts many of its effects on gene expression through reader proteins that bind specifically to m(6)A-containing transcripts. Fragile X mental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b80779121f355ddb982853ad0ca6b5e2
https://pubmed.ncbi.nlm.nih.gov/31753916
https://pubmed.ncbi.nlm.nih.gov/31753916
Publikováno v:
Human Molecular Genetics. 25:3395-3406
Spinal muscular atrophy (SMA), the leading genetic cause of infant mortality, predominantly affects high metabolic tissues including motor neurons, skeletal muscles and the heart. Although the genetic cause of SMA has been identified, mechanisms unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85008650711d0eda91df39a8fde438a
https://doi.org/10.1093/hmg/ddw262
https://doi.org/10.1093/hmg/ddw262
Autor:
Brittany M, Edens, Caroline, Vissers, Jing, Su, Saravanan, Arumugam, Zhaofa, Xu, Han, Shi, Nimrod, Miller, Francisca, Rojas Ringeling, Guo-Li, Ming, Chuan, He, Hongjun, Song, Yongchao C, Ma
Publikováno v:
Cell reports
SUMMARY N6-methyladenosine (m6A) modification of mRNA is emerging as a vital mechanism regulating RNA function. Here, we show that fragile X mental retardation protein (FMRP) reads m6A to promote nuclear export of methylated mRNA targets during neura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37998ba9411992fe02068322f72c1c25
https://pubmed.ncbi.nlm.nih.gov/31340148
https://pubmed.ncbi.nlm.nih.gov/31340148
Autor:
Zhihua Feng, Chien-Ping Ko, Thomas O. Crawford, Charlotte J. Sumner, Brittany M. Edens, Benjamin Taige Hong, Jorge A. Cantu, Christie C. Sze, Susan C. Su, Yong Chao Ma, Ben Yang, Jacek Topczewski, Long Ma, Nimrod Miller, Han Shi
Publikováno v:
The Journal of Neuroscience. 35:6038-6050
Mechanisms underlying motor neuron degeneration in spinal muscular atrophy (SMA), the leading inherited cause of infant mortality, remain largely unknown. Many studies have established the importance of hyperphosphorylation of the microtubule-associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e27737bba2dcaf09c4a034807ae550
https://doi.org/10.1523/jneurosci.3716-14.2015
https://doi.org/10.1523/jneurosci.3716-14.2015