Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nimol Kloeung"'
Autor:
Mélissa Mairet-Khedim, Camille Roesch, Nimol Khim, Sreynet Srun, Anthony Bouillon, Saorin Kim, Sopheakvatey Ke, Chhayleang Kauy, Nimol Kloeung, Rotha Eam, Chanra Khean, Chanvong Kul, Sophy Chy, Rithea Leang, Pascal Ringwald, Jean-Christophe Barale, Benoit Witkowski
Publikováno v:
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, 2023, 78 (2), pp.411-417. ⟨10.1093/jac/dkac403⟩
Journal of Antimicrobial Chemotherapy, 2023, 78 (2), pp.411-417. ⟨10.1093/jac/dkac403⟩
Background In early 2016, in Preah Vihear, Northern Cambodia, artesunate/mefloquine was used to cope with dihydroartemisinin/piperaquine-resistant Plasmodium falciparum parasites. Following this policy, P. falciparum strains harbouring molecular mark
Autor:
Saorin Kim, Chhayleang Kauy, Maria Dorina Bustos, Nimol Kloeung, Rotha Eam, Nimol Khim, Denis Mey Bouth, Sopheakvatey Ke, Brigitte Izac, Benoit Witkowski, Rithea Leang, Melissa Mairet-Khedim, Pascal Ringwald, Frédéric Ariey, Camille Marmai, Sophy Chy
Publikováno v:
Clinical Infectious Diseases
Clinical Infectious Diseases, Oxford University Press (OUP), 2021, 73 (3), pp.406-413. ⟨10.1093/cid/ciaa628⟩
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases, 2021, 73 (3), pp.406-413. ⟨10.1093/cid/ciaa628⟩
Clinical Infectious Diseases, Oxford University Press (OUP), 2021, 73 (3), pp.406-413. ⟨10.1093/cid/ciaa628⟩
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases, 2021, 73 (3), pp.406-413. ⟨10.1093/cid/ciaa628⟩
Background Artesunate-amodiaquine is a potential therapy for uncomplicated malaria in Cambodia. Methods Between September 2016 and January 2017, artesunate-amodiaquine efficacy and safety were evaluated in a prospective, open-label, single-arm observ
Autor:
Jean Christophe Barale, Chanra Khean, Nimol Khim, Sopheakvatey Ke, Saorin Kim, Benoit Witkowski, Nimol Kloeung, Didier Leboulleux, Pascal Ringwald, Didier Leroy, Didier Menard, Chhayleang Kauy, Rithea Leang, Rotha Eam, Flore Nardella, Alain Pellet, Melissa Mairet-Khedim
Publikováno v:
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (11), pp.3240-3244. ⟨10.1093/jac/dkz340⟩
Journal of Antimicrobial Chemotherapy, 2019, 74 (11), pp.3240-3244. ⟨10.1093/jac/dkz340⟩
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (11), pp.3240-3244. ⟨10.1093/jac/dkz340⟩
Journal of Antimicrobial Chemotherapy, 2019, 74 (11), pp.3240-3244. ⟨10.1093/jac/dkz340⟩
Background Cambodia is the epicentre of resistance emergence for virtually all antimalarial drugs. Selection and spread of parasites resistant to artemisinin-based combination therapy (ACT) is a major threat for malaria elimination, hence the need to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79452f4aa0339ba58daf2ec0fdb34d08
https://hal-pasteur.archives-ouvertes.fr/pasteur-02385376
https://hal-pasteur.archives-ouvertes.fr/pasteur-02385376
Autor:
Valentine Duru, Rekol Huy, Laurence Ma, David A. Fidock, Rotha Eam, Saorin Kim, Gregory Nuel, Benjamin Saintpierre, Christiane Bouchier, Sophy Chy, Didier Menard, Jean-Christophe Barale, Leila S. Ross, Odile Mercereau-Puijalon, Kaknika Loch, Eric Legrand, Benoit Witkowski, Frédéric Ariey, Johann Beghain, Chanra Khean, Rithea Leang, Anthony Bouillon, Nimol Khim, Malen Ken, Nimol Kloeung, Anais Domergue, Sopheakvatey Ke, Pascal Ringwald
Publikováno v:
The Lancet. Infectious Diseases
The Lancet Infectious Diseases
The Lancet Infectious Diseases, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩
The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2016, In Press, Corrected Proof, 〈http://www.sciencedirect.com/science/article/pii/S1473309916304157〉. 〈10.1016/S1473-3099(16)30415-7〉
The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩
The Lancet Infectious Diseases
The Lancet Infectious Diseases, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩
The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2016, In Press, Corrected Proof, 〈http://www.sciencedirect.com/science/article/pii/S1473309916304157〉. 〈10.1016/S1473-3099(16)30415-7〉
The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2016, 17 (2), pp.174-183. ⟨10.1016/S1473-3099(16)30415-7⟩
SummaryBackgroundWestern Cambodia is the epicentre of Plasmodium falciparum multidrug resistance and is facing high rates of dihydroartemisinin–piperaquine treatment failures. Genetic tools to detect the multidrug-resistant parasites are needed. Ar
Autor:
Rithea Leang, Sophie Chy, Antoine Berry, Pascal Ringwald, Saorin Kim, Odile Mercereau-Puijalon, Rupam Tripura, Pheaktra Chim, Socheat Duong, Françoise Benoit-Vical, Jean-Christophe Barale, Didier Menard, Nimol Kloeung, Nimol Khim, Olivier Gorgette, Sopheakvatey Ke, Benoit Witkowski, Frédéric Ariey, Arjen M. Dondorp
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 2013, 57 (2), pp.914-923. ⟨10.1128/AAC.01868-12⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2013, 57 (2), pp.914-923. ⟨10.1128/AAC.01868-12⟩
Antimicrobial Agents and Chemotherapy, 2013, 57 (2), pp.914-923. ⟨10.1128/AAC.01868-12⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2013, 57 (2), pp.914-923. ⟨10.1128/AAC.01868-12⟩
The declining efficacy of artemisinin derivatives against Plasmodium falciparum in western Cambodia is a major concern. The knowledge gap in the understanding of the mechanisms involved hampers designing monitoring tools. Here, we culture-adapted 20
Autor:
Anais Domergue, Odile Mercereau-Puijalon, Rithea Leang, Malen Ken, Dysoley Lek, Johann Beghain, Benoit Witkowski, Nimol Khim, Kaknika Loch, Rekol Huy, Frédéric Ariey, Saorin Kim, Chanra Khean, Nimol Kloeung, Valentine Duru, Rotha Eam, Philippe J Guerin, Sophy Chy, Didier Menard, Sopheakvatey Ke
Publikováno v:
BMC Medicine
BMC Medicine, BioMed Central, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩
BMC Medicine, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩
BMC Medicine, BioMed Central, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩
BMC Medicine, 2015, 13 (1), pp.305. ⟨10.1186/s12916-015-0539-5⟩
Background The declining efficacy of dihydroartemisinin-piperaquine against Plasmodium falciparum in Cambodia, along with increasing numbers of recrudescent cases, suggests resistance to both artemisinin and piperaquine. Available in vitro piperaquin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2859730365064376e124365485e9dce
https://hal.archives-ouvertes.fr/hal-02560638/document
https://hal.archives-ouvertes.fr/hal-02560638/document
Autor:
Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
Flow chart of patients included in the final analysis of the 2014 retrospective study. Cambodia 2014 and isolates used in ex vivo assays. (PDF 52 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f6722a3a496948067000eb341120d1
Autor:
Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
In vitro piperaquine survival assay survival rate distribution in 32 culture-adapted P. falciparum isolates from Cambodia in 2012 according to mutations or copy number variation in candidate genes significantly associated with piperaquine resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fccd5cfd8d8017f4d42b1a42c09371
Autor:
Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
Patient information and corresponding data from ex vivo piperaquine survival assays performed on P. falciparum isolates from Rattanakiri, Siem Reap, Stung Treng and Mondulkiri provinces in 2014. (PDF 77 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5666633cdb884e016017171986397f83
Autor:
Duru, Valentine, Nimol Khim, Rithea Leang, Saorin Kim, Anais Domergue, Nimol Kloeung, Sopheakvatey Ke, Chy, Sophy, Rotha Eam, Chanra Khean, Kaknika Loch, Ken, Malen, Dysoley Lek, Beghain, Johann, FrĂŠdĂŠric Ariey, Guerin, Philippe, Rekol Huy, Mercereau-Puijalon, Odile, Benoit Witkowski, Menard, Didier
Results of the piperaquine concentration measurements in culture supernatants of different wells in plate used for the classical isotopic assay, containing increasing piperaquine concentrations (from 1.91 nM in PPQ11 to 2000 nM in PPQ1). (DOCX 12 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973c6693bc37316f612455590bfb7e82