Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nimna S. Ranatunga"'
Autor:
Nimna S. Ranatunga, Susan L. Forsburg
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 10, Pp 3049-3063 (2016)
The minichromosome maintenance (MCM) complex is the conserved helicase motor of the eukaryotic replication fork. Mutations in the Mcm4 subunit are associated with replication stress and double strand breaks in multiple systems. In this work, we chara
Externí odkaz:
https://doaj.org/article/a6e4892f3b6a488d88b3990998585e15
Autor:
Susan L. Forsburg, Nimna S. Ranatunga
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 10, Pp 3049-3063 (2016)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
The minichromosome maintenance (MCM) complex is the conserved helicase motor of the eukaryotic replication fork. Mutations in the Mcm4 subunit are associated with replication stress and double strand breaks in multiple systems. In this work, we chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0edf99b2ba4c26091ac4cc9d5e3eef
http://g3journal.org/lookup/doi/10.1534/g3.116.033571
http://g3journal.org/lookup/doi/10.1534/g3.116.033571
Publikováno v:
Molecular Biology of the Cell
Unable to complete S phase, a fission yeast MCM mutant evades the mitotic checkpoint, causing aneuploidy, chromosome fragments, and bridges. The formation of apparent yeast micronuclei that are membrane bound is shown in real time; they develop DNA d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba1ab678d45ac17e0c4f161ed3eb6b5
http://europepmc.org/articles/PMC4591689
http://europepmc.org/articles/PMC4591689
Autor:
Daniel B. Toso, Yang Fu, Z. Hong Zhou, Nimna S. Ranatunga, Ian Slaymaker, Xiaojiang S. Chen, Aaron S. Brewster, Susan L. Forsburg
Publikováno v:
Nucleic Acids Research
Deregulation of mini-chromosome maintenance (MCM) proteins is associated with genomic instability and cancer. MCM complexes are recruited to replication origins for genome duplication. Paradoxically, MCM proteins are in excess than the number of orig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daef7f163da5f8538a40257caf1b7c8d
https://pubmed.ncbi.nlm.nih.gov/23361460
https://pubmed.ncbi.nlm.nih.gov/23361460
Autor:
Xiaojiang S. Chen, Aaron S. Brewster, Daniel B. Toso, Ian Slaymaker, Yang Fu, Z. Hong Zhou, Susan L. Forsburg, Nimna S. Ranatunga
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 31:78-79
Deregulation of mini-chromosome maintenance (MCM) proteins are associated with genomic instability and cellular abnormality. MCM complexes are recruited to replication origins for S phase genome duplication. Paradoxically, MCM proteins are expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c675611cbdf66b0361d491aad4803dd
https://doi.org/10.1080/07391102.2013.786365
https://doi.org/10.1080/07391102.2013.786365