Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nimmashetti Naganna"'
Publikováno v:
ACS Omega, Vol 5, Iss 6, Pp 2690-2698 (2020)
Externí odkaz:
https://doaj.org/article/37bedbeca966411599aa0f5ef3109a4f
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 6, Pp 2690-2698 (2020)
ACS Omega, Vol 5, Iss 6, Pp 2690-2698 (2020)
Ponatinib is a multikinase inhibitor that is used to treat chronic myeloid leukemia patients harboring mutated ABL1(T315I) kinase. Due to the potent inhibition of FLT3, RET, and fibroblast growth factor receptors (FGFRs), it is also being evaluated a
Publikováno v:
Organicbiomolecular chemistry. 17(30)
The use of peptides as therapeutics has been growing due to their biocompatibility. Solid phase peptide synthesis typically used to access these peptides requires excess reagents and/or microwave irradiation to drive reactions to completion because t
Ponatinib is a multikinase inhibitor that is used to treat chronic myeloid leukemia patients harboring mutated ABL1(T315I) kinase. Due to the potent inhibition of FLT3, RET and FGFRs, it is also being evaluated against AML, biliary and lung cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f8b6a9fd5f5d83ede6b35d3a989f41
https://doi.org/10.26434/chemrxiv.7325162
https://doi.org/10.26434/chemrxiv.7325162
Autor:
Nandita Madhavan, Nimmashetti Naganna
Publikováno v:
RSC Advances. 5:93027-93031
Soluble polymers that can be readily isolated via precipitation and possess multiple amino acid attachment sites are highly attractive for peptide synthesis. Polyethylene glycol supports that solubilize the growing peptide chain and can be readily is
Autor:
Nandita Madhavan, Nimmashetti Naganna
Publikováno v:
IndraStra Global.
Solid-phase peptide synthesis has been an attractive method for synthesizing peptides because it is quick and can be automated. The heterogeneous reaction medium in solid-phase peptide synthesis necessitates the use of large equivalents of reagents t
Autor:
Nandita Madhavan, Nimmashetti Naganna
Publikováno v:
IndraStra Global.
Poly(norbornene) supports comprising solubilizing ethylene glycol units and multiple amino acid attachment sites have been developed for peptide synthesis. A variety of amino acids have been efficiently loaded (0.6-1.1 mmol/g) onto the support in hig