Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nimish K. Acharya"'
Autor:
Eric L. Goldwaser, Randel L. Swanson, Edgardo J. Arroyo, Venkat Venkataraman, Mary C. Kosciuk, Robert G. Nagele, L. Elliot Hong, Nimish K. Acharya
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
Though hippocampal volume reduction is a pathological hallmark of schizophrenia, the molecular pathway(s) responsible for this degeneration remains unknown. Recent reports have suggested the potential role of impaired blood-brain barrier (BBB) functi
Externí odkaz:
https://doaj.org/article/842c1a1ee00b414cba7bacbfa489e27b
Autor:
Cassandra A. DeMarshall, Eric P. Nagele, Abhirup Sarkar, Nimish K. Acharya, George Godsey, Eric L. Goldwaser, Mary Kosciuk, Umashanger Thayasivam, Min Han, Benjamin Belinka, Robert G. Nagele, Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 3, Iss 1, Pp 51-62 (2016)
Abstract Introduction There is an urgent need to identify biomarkers that can accurately detect and diagnose Alzheimer's disease (AD). Autoantibodies are abundant and ubiquitous in human sera and have been previously demonstrated as disease‐specifi
Externí odkaz:
https://doaj.org/article/8fac21f2aa454f0492d14a499fa13658
Autor:
Clara Zhu, Georgianna Sandilos, John Williamson, Robert Emery, Rebecca Platoff, Upasana Joneja, Nimish K. Acharya, Andrew Lin, Jeremy Badach, Brian Zilberman, Jozef Madzo, Jaroslav Jelinek, Ping Zhang, Young Ki Hong
Publikováno v:
Surgery. 173:1045-1051
Publikováno v:
Cureus.
Traumatic brain injury (TBI) exposure has been associated with an increased risk of age-related cognitive decline or dementia in multiple epidemiological studies. Current therapeutic interventions in the field of Brain Injury Medicine focus largely o
Autor:
Abhirup Sarkar, Hao Wu, Eric L. Goldwaser, Mary C. Kosciuk, George A. Godsey, Robert G. Nagele, Nimish K. Acharya, Cassandra DeMarshall
Publikováno v:
Journal of Alzheimer's Disease
Blood-brain barrier (BBB) permeability is a recognized early feature of Alzheimer's disease (AD). In the present study, we examined consequences of increased BBB permeability on the development of AD-related pathology by tracking selected leaked plas
Autor:
Eric P Nagele, Min Han, Nimish K Acharya, Cassandra DeMarshall, Mary C Kosciuk, Robert G Nagele
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60726 (2013)
The presence of self-reactive IgG autoantibodies in human sera is largely thought to represent a breakdown in central tolerance and is typically regarded as a harbinger of autoimmune pathology. In the present study, immune-response profiling of human
Externí odkaz:
https://doaj.org/article/16c67cad77854cf8a2a52afafada0fc4
Autor:
Eric L. Goldwaser, Mary C. Kosciuk, Venkat Venkataraman, George A. Godsey, Theresa A. Freeman, Robert G. Nagele, Hao Wu, Xin Qi, Robert L. Wilensky, Nimish K. Acharya, Colin H. Macphee
Publikováno v:
Diabetes and Vascular Disease Research. 14:200-213
Using a porcine model of diabetes mellitus and hypercholesterolaemia, we previously showed that diabetes mellitus and hypercholesterolaemia is associated with a chronic increase in blood–brain barrier permeability in the cerebral cortex, leading to
Publikováno v:
Journal of Alzheimer's Disease. 54:445-456
Alzheimer's disease (AD) and diabetes mellitus (DM) are among the most pervasive and devastating disorders that afflict people throughout the world. Although typically associated with older demographics, recent epidemiologic studies have reported par
Autor:
Umashanger Thayasivam, Eric P. Nagele, Abhirup Sarkar, Alzheimer's Disease Neuroimaging Initiative, Benjamin Belinka, Eric L. Goldwaser, Robert G. Nagele, Mary C. Kosciuk, Nimish K. Acharya, George A. Godsey, Min Han, Cassandra DeMarshall
Publikováno v:
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 3, Iss 1, Pp 51-62 (2016)
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 3, Iss 1, Pp 51-62 (2016)
Introduction There is an urgent need to identify biomarkers that can accurately detect and diagnose Alzheimer's disease (AD). Autoantibodies are abundant and ubiquitous in human sera and have been previously demonstrated as disease‐specific biomark
Autor:
Cristina A. Johnson, Douglas M. Leonard, Jacqueline M. Dash, Denah M. Appelt, Martin M. Forsberg, Nimish K. Acharya, Eric L. Goldwaser, Mary C. Kosciuk, Cassandra DeMarshall, George A. Godsey, Robert G. Nagele, Abhirup Sarkar, Caitlin P. Hale
Publikováno v:
Brain Research. 1620:29-41
A large percentage of patients subjected to general anesthesia at 65 years and older exhibit postoperative delirium (POD). Here, we test the hypothesis that inhaled anesthetics (IAs), such as Sevoflurane and Isoflurane, act directly on brain vascular