Zobrazeno 1 - 10
of 531
pro vyhledávání: '"Nimesh S"'
Autor:
Ming‐Zher Poh, Anthony J. Battisti, Li‐Fang Cheng, Janice Lin, Anil Patwardhan, Ganesh S. Venkataraman, Charles A. Athill, Nimesh S. Patel, Chinmay P. Patel, Christian E. Machado, Jeffrey T. Ellis, Lori A. Crosson, Yuriko Tamura, R. Scooter Plowman, Mintu P. Turakhia, Hamid Ghanbari
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 19 (2023)
Background Wearable devices may be useful for identification, quantification and characterization, and management of atrial fibrillation (AF). To date, consumer wrist‐worn devices for AF detection using photoplethysmography‐based algorithms perfo
Externí odkaz:
https://doaj.org/article/98723ac9697748189eb5d5ac1ce52cc5
Autor:
Jenny Blythe, Nimesh S. A. Patel, Will Spiring, Graham Easton, Dason Evans, Egle Meskevicius-Sadler, Hassan Noshib, Heather Gordon
Publikováno v:
BMC Medical Education, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background The Covid pandemic and associated lockdown forced medical schools globally not only to deliver emergency remote teaching, but to consider alternative methods of high stakes assessment. Here we outline our approach to the resit vir
Externí odkaz:
https://doaj.org/article/965e048af9724281afe52c187a728bf8
Autor:
Mansoor Nawaz Bangash, Tom E. F. Abbott, Nimesh S. A. Patel, Charles Johnston Hinds, Christoph Thiemermann, Rupert Mark Pearse
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: The β2-adrenoceptor agonist dopexamine may possess anti-inflammatory actions which could reduce organ injury during endotoxemia and laparotomy. Related effects on leucocyte-endothelial adhesion remain unclear.Methods: Thirty anesthetized
Externí odkaz:
https://doaj.org/article/108d926220474df392c0812ab69e8b0b
Autor:
Jale Yuzugulen, Julie A. Douthwaite, Elizabeth G. Wood, Inmaculada C. Villar, Nimesh S. A. Patel, James Jegard, Hubert Gaertner, Irène Rossitto-Borlat, Keith Rose, Oliver Hartley, Pedro R. Cutillas, Amrita Ahluwalia, Roger Corder
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Endothelin-1 (ET-1) is involved in the pathogenesis of cardiac and renal diseases, and in the progression of tumour growth in cancer, but current diagnosis and treatment remain inadequate. Peptides derived from the 212 amino acid precursor p
Externí odkaz:
https://doaj.org/article/c88405d4ef9a4272ab9b01473d274a6f
Autor:
Florence L. Johnson, Nimesh S. A. Patel, Gareth S. D. Purvis, Fausto Chiazza, Jianmin Chen, Regina Sordi, Guillaume Hache, Viktoria V. Merezhko, Massimo Collino, Muhammed M. Yaqoob, Christoph Thiemermann
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 7 (2017)
BackgroundAcute kidney injury (AKI) is a major risk factor for the development of chronic kidney disease. Nuclear factor‐κB is a nuclear transcription factor activated post‐ischemia, responsible for the transcription of proinflammatory proteins.
Externí odkaz:
https://doaj.org/article/c7a32313b4ea4cdfada5330912344727
Autor:
Areeg I. Khan, Sina M. Coldewey, Nimesh S. A. Patel, Mara Rogazzo, Massimo Collino, Muhammed M. Yaqoob, Peter Radermacher, Amar Kapoor, Christoph Thiemermann
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 4, Pp 1021-1030 (2013)
SUMMARY There is limited evidence that the tissue-protective effects of erythropoietin are mediated by a heterocomplex of the erythropoietin receptor and the β-common receptor (‘tissue-protective receptor’), which is pharmacologically distinct f
Externí odkaz:
https://doaj.org/article/c60206591bad4244a1df5c36426a8626
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 4, Pp 1031-1042 (2013)
SUMMARY Nuclear factor κB (NF-κB) plays a pivotal role in sepsis. Activation of NF-κB is initiated by the signal-induced ubiquitylation and subsequent degradation of inhibitors of kappa B (IκBs) primarily via activation of the IκB kinase (IKK).
Externí odkaz:
https://doaj.org/article/3a277bb0cf3642d2ae0882d54bc51793
Autor:
Kiran K. Nandra, Massimo Collino, Mara Rogazzo, Roberto Fantozzi, Nimesh S. A. Patel, Christoph Thiemermann
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 3, Pp 701-709 (2013)
SUMMARY Pre-treatment with erythropoietin (EPO) has been demonstrated to exert tissue-protective effects against ‘ischemia-reperfusion’-type injuries. This protection might be mediated by mobilization of bone marrow endothelial progenitor cells (
Externí odkaz:
https://doaj.org/article/594f2973fb2a47d28951feb4e68d9fae
Autor:
Regina Sordi, Fausto Chiazza, Nimesh S A Patel, Rachel A Doyle, Massimo Collino, Christoph Thiemermann
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122096 (2015)
Male rats were 'pretreated' with phosphate-buffered saline (PBS; i.p.) or LPS (1 mg/kg; i.p.) 24 h prior to HS. Mean arterial pressure (MAP) was maintained at 30 ± 2 mmHg for 90 min or until 25% of the shed blood had to be re-injected to sustain MAP
Externí odkaz:
https://doaj.org/article/f5a4b0b6568a40b9ac024412690fc09c
Autor:
Jianmin Chen, Fausto Chiazza, Massimo Collino, Nimesh S A Patel, Sina M Coldewey, Christoph Thiemermann
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100631 (2014)
Development of cardiac dysfunction is associated with increased morbidity and mortality in patients with sepsis. Increasing evidence shows that gender determines the degree of inflammatory response of the host and that females tolerate sepsis better
Externí odkaz:
https://doaj.org/article/d038a1cde9254ff8b13322c0dbe3d270