Výsledky vyhledávání - "Nimesh Adhikari"

CLO19-050: Risk of Health- Related Quality of Life (HRQOL) Events in Patients With Advanced Solid Tumors Treated With Cabozantinib: A Combined Analysis of Four Phase 3 Randomized Controlled Trials

Autor: Sriman Swarup, Nimesh Adhikari, Anita Sultan, Myo Zaw, Ye Aung, Kyaw Zin Thein, Yin Mon Myat, Nusrat Jahan, Upama Sharma

Publikováno v: Journal of the National Comprehensive Cancer Network. 17:CLO19-050

Background: VEGFR, KIT, RET, and MET pathways are implicated in several solid tumors. Cabozantinib is an oral inhibitor of these kinase pathways, and hence has found its use in treatment of multiple malignancies. However, it has several side effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47360a58d2ea8083b38fd60961221fef
https://doi.org/10.6004/jnccn.2018.7150

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CLO19-051: CDK 4/6 Inhibitor-Associated Hematologic Toxicities and Febrile Neutropenia in Patients With Hormone Receptor-Positive HER2-Negative Metastatic Breast Cancer

Autor: Yin Mon Myat, Somedeb Ball, Nimesh Adhikari, Catherine Jones, Anita Sultan, Sriman Swarup, Kyaw Zin Thein, Myo H. Zaw, Francis Mogollon-Duffo

Publikováno v: Journal of the National Comprehensive Cancer Network. 17:CLO19-051

Background: Breast cancer is the most common cancer in women, and the majority of breast cancers express the estrogen receptor or progesterone receptor. Inhibition of CDK4/6 signaling pathway has shown survival benefit in advanced breast cancer by ov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4b0b4bbc0fbf3cefb2dea7c939c61ca
https://doi.org/10.6004/jnccn.2018.7152

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CLO19-024: Risk of Atrial Fibrillation and Pulmonary Toxicities in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Treated With Ibrutinib

Autor: Khaing Khaing Htwe, Anita Sultan, Tun W. Naing, Upama Sharma, Kyaw Zin Thein, Myo H. Zaw, Wai P. Thi, Sriman Swarup, Nimesh Adhikari, Nay N. Yee

Publikováno v: Journal of the National Comprehensive Cancer Network. 17:CLO19-024

Background: Bruton’s tyrosine kinase (BTK), a kinase downstream of the B-cell receptor, involves in the B cell survival and proliferation and has become an attractive therapeutic target. Ibrutinib is an oral potent, covalent inhibitor of BTK and he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a87cb3ee2c2da6df6d1ad9a7b2175b8a
https://doi.org/10.6004/jnccn.2018.7158

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Relative risk of hepatotoxicity associated with cyclin-dependent kinase inhibitors (CDK4/6i): A systematic review and meta-analysis of phase 3 randomized controlled trials

Autor: Shabnam Rehman, Sariya Wongsaengsak, Arrvind Raghunath, Lukman Aderoju Tijani, Nimesh Adhikari, Nusrat Jahan

Publikováno v: Journal of Clinical Oncology. 39:e13037-e13037

e13037 Background: Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) such as palbociclib, abemaciclib, and ribociclib have changed the landscape of management of estrogen receptor-positive and HER2-negative breast cancer in recent years. We conducted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d139ac9e3a9b769be69ec871c3c952f
https://doi.org/10.1200/jco.2021.39.15_suppl.e13037

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Phosphatidylinositol 3-Kinase (PI3K) Inhibitors-Related Hematological Toxicities in Patients with Relapsed and Refractory Chronic Lymphocytic Leukemia/ Small Lymphocytic Lymphoma

Autor: Ei Moe Phyu, Anita Sultan, Thura Win Htut, Sriman Swarup, Nyein Htway Yu, Myat Min Han, Bradley J. Grant, Kyaw Zin Thein, Nimesh Adhikari, Myint Aung Win, Nicholas D'Cunha, Yin Mon Myat, Chandler Graf, Donald P. Quick

Publikováno v: Blood. 134:5877-5877

Introduction: Chronic lymphocytic leukemia is the most prevalent adult leukemia in western countries. Phosphatidylinositol 3-kinase (PI3K) is a kinase protein involved in downstream signaling for the B-cell receptor signaling pathway and has been sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::893f4829b7ba7de6d6f0bcfd50f73642
https://doi.org/10.1182/blood-2019-123531

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Effective Implementation of a Structured Protocol for Facilitation of the Judicious Use of Antibody Test for Diagnosis of Heparin Induced Thrombocytopenia

Autor: Khatrina Swarup, Lukman Tijani, Nimesh Adhikari, Anita Sultan, Kyaw Zin Thein, Somedeb Ball, Francis Mogollon Duffo, Shabnam Rehman, Meda Srikala, Sriman Swarup

Publikováno v: Blood. 134:3462-3462

Introduction: Heparin induced thrombocytopenia (HIT) is a serious prothrombotic condition, usually triggered by exposure to heparin products with formation of antibodies to platelet factor 4/ heparin polyanion complexes. Diagnostic algorithm for HIT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6befee47babfde0b7aa8ed3069f3d1d
https://doi.org/10.1182/blood-2019-127249

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Tolerability in Patients with Multiple Myeloma Treated with Daratumumab: A Systematic Review and Meta-Analysis of Phase III Randomized Controlled Trials

Autor: Ei Moe Phyu, Kyaw Zin Thein, Lukman Tijani, Yin Mon Myat, Donald P. Quick, Myint Aung Win, Nicholas D'Cunha, Sriman Swarup, Nimesh Adhikari, Anita Sultan, Thura Win Htut, Akshar Dash, Myat Min Han, Sanjay Awasthi

Publikováno v: Blood. 134:1873-1873

Introduction: Multiple myeloma, which accounts for 1% of all cancers, is a hematologic cancer in which clonal plasma-cell proliferation leads to complications and death. Over the recent years, it has shown that the introduction of novel agents, inclu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92e540713643ad80e4642765bc7fac6f
https://doi.org/10.1182/blood-2019-123164

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Efficacy of Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma: A Combined Analysis of Three Phase III Randomized Controlled Trials

Autor: Ye Aung, Thura Win Htut, Fred Hardwicke, Sriman Swarup, Nicholas D'Cunha, Nimesh Adhikari, Kyaw Zin Thein, Pwint Phyu Hlaing, Lukman Tijani, Yin Mon Myat, Donald P. Quick, Anita Sultan, Myat Min Han, Upama Sharma

Publikováno v: Blood. 134:5479-5479

Introduction: The B-cell receptor signaling pathway involves in the pathogenesis of chronic lymphocytic leukemia/ small lymphocytic lymphoma (CLL/ SLL), the most common adult lymphoproliferative disorder in western countries. Ibrutinib, a novel Bruto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e965d1336deee4cdb9bdf372253cf79
https://doi.org/10.1182/blood-2019-123172

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