Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nimer Mehyar"'
Autor:
Nimer Mehyar
Publikováno v:
Journal of Virus Eradication, Vol 9, Iss 2, Pp 100327- (2023)
Introduction: The recent outbreak of SARS-CoV-2 has significantly increased the need to find inhibitors that target the essential enzymes for viral replication in host cells. This systematic review was conducted to identify potential inhibitors of SA
Externí odkaz:
https://doaj.org/article/ee2d1230ec4a4a1c9f94e3abdb723343
Autor:
Zeyad Alehaideb, Nimer Mehyar, Mai Al Ajaji, Mohammed Alassiri, Manal Alaamery, Bader Al Debasi, Bandar Alghanem, Jahad Alghamdi, Bahauddeen M. Alrfaei, Barrak Al Somaie, Ahmed Bakillah, Tlili Barhoumi, Yosra Boudjelal, Ibrahim Bushnak, Majid Alfadhel, Sheraz Gul, Imadul Islam, Mo Li, Theam Soon Lim, Salam Massadeh, Lamis Mouyes, Adel Nefzi, Atef Nehdi, Wyatt Yue, Ahmed Alaskar, Mohamed Boudjelal
Publikováno v:
Proceedings, Vol 43, Iss 1, p 6 (2020)
Following the success of our first therapeutic discovery conference in 2017 and the selection of King Abdullah International Medical Research Centre (KAIMRC) as the first Phase 1 clinical site in the Kingdom of Saudi Arabia, we organized our second c
Externí odkaz:
https://doaj.org/article/b0d1d6ad7de6437eae0dd94aec9ea656
Autor:
Abdullah Mashhour, Ahmed Alaskar, B A Somaie, Y Alobaida, S Alkhaldi, Imadul Islam, H A Alhadrami, Nimer Mehyar, A M Tolah, M Al Ghobain, Bandar Alghanem, Mohamed Boudjelal
Publikováno v:
SAR and QSAR in Environmental Research. 32:963-983
The coronavirus helicase is an essential enzyme required for viral replication/transcription pathways. Structural studies revealed a sulphate moiety that interacts with key residues within the nucleotide-binding site of the helicase. Compounds with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eec2fc9c4c6136b4cb1c2dadb6a66d5
https://doi.org/10.1080/1062936x.2021.1993995
https://doi.org/10.1080/1062936x.2021.1993995
Autor:
Mohamed Boudjelal, Imadul Islam, A S Askar, Sheraz Gul, A O Adedeji, Nimer Mehyar, Abdullah Mashhour
Publikováno v:
SAR and QSAR in Environmental Research
A Förster resonance energy transfer (FRET)-based assay was used to screen the FDA-approved compound library against the MERS-CoV helicase, an essential enzyme for virus replication within the host cell. Five compounds inhibited the helicase activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc9bf807d0b66226a999bfbd8faa0a5
Publikováno v:
Journal of infection in developing countries, 15(4):450-462
Rare diseases frequently attack and weaken the immune system, increasing the patient’s vulnerability to develop severe conditions after viral infections, such as COVID-19. Many patients with rare diseases also suffer from mental retardation and dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3947dd6999c93582245201df182bb352
https://pubmed.ncbi.nlm.nih.gov/33956643
https://pubmed.ncbi.nlm.nih.gov/33956643
Autor:
Ibrahim Bushnak, Nimer Mehyar, Jahad Alghamdi, Manal Alaamery, Mai Al Ajaji, Theam Soon Lim, Imadul Islam, Bandar Alghanem, Mohamed Boudjelal, Ahmed Bakillah, Sheraz Gul, Ahmed Alaskar, Majid Alfadhel, Barrak Al Somaie, Mohammed Alassiri, Mo Li, Atef Nehdi, Adel Nefzi, Tlili Barhoumi, Salam Massadeh, Bader Al Debasi, Zeyad Alehaideb, Yosra Boudjelal, Bahauddeen M. Alrfaei, Wyatt Yue, Lamis Mouyes
Publikováno v:
Proceedings, Vol 43, Iss 6, p 6 (2020)
Following the success of our first therapeutic discovery conference in 2017 and the selection of King Abdullah International Medical Research Centre (KAIMRC) as the first Phase 1 clinical site in the Kingdom of Saudi Arabia, we organized our second c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7cd35b92925b580268cedf2c2af5f2
https://www.mdpi.com/2504-3900/43/1/6
https://www.mdpi.com/2504-3900/43/1/6
Autor:
Nimer Mehyar
Adenosine 5′-triphosphate (ATP) can release hexokinase I (HKI) from its binding site on the outer mitochondrial membrane, but the mechanism of ATP release of HKI from mitochondria is unclear. ATP binds to the C-terminal half of HKI as a substrate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0751429deb2d5f985c96c4e2ba41e29
https://doi.org/10.31274/etd-180810-2151
https://doi.org/10.31274/etd-180810-2151
Autor:
Nimer Mehyar
The objective of this study was to investigate the effect of daily glucagon subcutaneous injections of 15 mg and oral administration of 400 mL glycerol during the first 14 d postpartum on the rates of gluconeogenesis in liver and lipogenesis and lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abd9001f0e67fffed2e9c85f6f781862
https://doi.org/10.31274/etd-180810-912
https://doi.org/10.31274/etd-180810-912
Mechanism of ATP‐dependent release of wild type and mutant human brain hexokinases from mitochondria
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbeed9c2ac261720f25ddcfa6f3cbc54
https://doi.org/10.1096/fasebj.24.1_supplement.510.6
https://doi.org/10.1096/fasebj.24.1_supplement.510.6