Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nima Ghitani"'
Autor:
Laura K. Case, Jaquette Liljencrantz, Nicholas Madian, Aaron Necaise, Justin Tubbs, Micaela McCall, Megan L. Bradson, Marcin Szczot, Mark H. Pitcher, Nima Ghitani, Eleni Frangos, Jonathan Cole, Diana Bharucha-Goebel, Dimah Saade, Tracy Ogata, Sandra Donkervoort, A. Reghan Foley, Carsten G. Bönnemann, Håkan Olausson, M. Catherine Bushnell, Alexander T. Chesler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The mechanisms underlying deep pressure sensing are not fully understood. Here the authors demonstrate that while two individuals lacking Aβ fibers demonstrate impaired deep pressure sensing, seven individuals with PIEZO2 loss of function mutations
Externí odkaz:
https://doaj.org/article/b005162b0b26483ea9700b4ecfd44b19
Autor:
Nima Ghitani, Alexander T. Chesler
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2121-2122 (2019)
Soohong et al. (2019) reveal a class of vagal afferents—defined by Piezo2 expression—that innervate the aorta and function to sense blood pressure fluctuations. Their study describes the morphologies and role of these neurons in vascular regulati
Externí odkaz:
https://doaj.org/article/939c663349b94d8cba81c807498624c9
Autor:
Ardem Patapoutian, Alexander T. Chesler, Jason A. Keller, Marcin Szczot, Carsten G. Bönnemann, Adam Coombs, Ihab Daou, Lisa Stowers, Dimah Saade, Kara L. Marshall, Tracy Ogata, Nima Ghitani
Publikováno v:
Nature
Henry Miller stated that "to relieve a full bladder is one of the great human joys". Urination is critically important in health and ailments of the lower urinary tract cause high pathological burden. Although there have been advances in understandin
Autor:
Justin D. Tubbs, Laura K. Case, Eleni Frangos, Diana Bharucha-Goebel, Nima Ghitani, Håkan Olausson, Dimah Saade, Mark H. Pitcher, Jonathan Cole, Nicholas Madian, Aaron Necaise, Micaela V. McCall, Jaquette Liljencrantz, Marcin Szczot, Alexander T. Chesler, Sandra Donkervoort, A. Reghan Foley, Megan Bradson, Tracy Ogata, Carsten G. Bönnemann, M. Catherine Bushnell
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The sensation of pressure allows us to feel sustained compression and body strain. While our understanding of cutaneous touch has grown significantly in recent years, how deep tissue sensations are detected remains less clear. Here, we use quantitati
Autor:
Lars J. von Buchholtz, Nicholas J. P. Ryba, Alexander T. Chesler, Julia A. Licholai, Nima Ghitani, Ruby M. Lam
Publikováno v:
Neuron
Summary Single-cell RNA-sequencing and in vivo functional imaging provide expansive but disconnected views of neuronal diversity. Here, we developed a strategy for linking these modes of classification to explore molecular and cellular mechanisms res
Publikováno v:
Ghitani, N; Bayguinov, PO; Basso, MA; & Jackson, MB. (2016). A sodium afterdepolarization in rat superior colliculus neurons and its contribution to population activity.. Journal of neurophysiology, 116(1), 191-200. doi: 10.1152/jn.01138.2015. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2kq054d1
The mammalian superior colliculus (SC) is a midbrain structure that integrates multimodal sensory inputs and computes commands to initiate rapid eye movements. SC neurons burst with the sudden onset of a visual stimulus, followed by persistent activi
Autor:
Diana Bharucha-Goebel, Ruby M. Lam, Laura K. Case, James H. Thompson, Dimah Saade, Taylor Gordon, Aaron Necaise, Arnab Barik, Jaquette Liljencrantz, Carsten G. Bönnemann, M. Catherine Bushnell, Sandra Donkervoort, Alexander T. Chesler, A. Reghan Foley, Nima Ghitani, Marcin Szczot
Tissue injury and inflammation markedly alter touch perception, making normally innocuous sensations become intensely painful. Although this sensory distortion, known as tactile allodynia, is one of the most common types of pain, the mechanism by whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171e6301b1cb5845bd3132f26f4c4d62
https://europepmc.org/articles/PMC6875774/
https://europepmc.org/articles/PMC6875774/
Publikováno v:
Journal of Neurophysiology. 113:1249-1259
Genetically encoded voltage sensors expand the optogenetics toolkit into the important realm of electrical recording, enabling researchers to study the dynamic activity of complex neural circuits in real time. However, these probes have thus far perf
Publikováno v:
Neuron. 100:1491-1503.e3
Summary Response to danger needs to be rapid and appropriate. In humans, nocifensive behaviors often precede conscious pain perception. Much is known about local spinal cord circuits for simple reflexive responses, but the mechanisms underlying more
Publikováno v:
Journal of neurophysiology, vol 114, iss 1
Bayguinov, PO; Ghitani, N; Jackson, MB; & Basso, MA. (2015). A hard-wired priority map in the superior colliculus shaped by asymmetric inhibitory circuitry. Journal of Neurophysiology, 114(1), 662-676. doi: 10.1152/jn.00144.2015. UCLA: Retrieved from: http://www.escholarship.org/uc/item/93g1g6tq
Bayguinov, PO; Ghitani, N; Jackson, MB; & Basso, MA. (2015). A hard-wired priority map in the superior colliculus shaped by asymmetric inhibitory circuitry. Journal of Neurophysiology, 114(1), 662-676. doi: 10.1152/jn.00144.2015. UCLA: Retrieved from: http://www.escholarship.org/uc/item/93g1g6tq
© 2015 the American Physiological Society. The mammalian superior colliculus (SC) is a laminar midbrain structure that translates visual signals into commands to shift the focus of attention and gaze. The SC plays an integral role in selecting targe