Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nima Akhavein"'
Autor:
Nima Akhavein, Marc M. Baum, Manjula Gunawardana, John A. Moss, Sandrine Calvez, Mariana Remedios-Chan, Rob Fanter, Steve Lenhard, Samantha Rusk, Leonard Azzarano, Deborah McCoy, Beat Jucker, Brian Johns, Matt Burke, Emile Velthuisen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract GSK2838232 (GSK8232) is a second-generation maturation inhibitor (MI) developed for the treatment of HIV with excellent broad-spectrum virological profiles. The compound has demonstrated promising clinical results as an orally administered a
Externí odkaz:
https://doaj.org/article/a3f234e950404360a54ad36a6723e69e
Autor:
Alejandro J. Paredes, Andi Dian Permana, Fabiana Volpe-Zanutto, Muhammad Nur Amir, Lalitkumar K. Vora, Ismaiel A. Tekko, Nima Akhavein, Andrew D. Weber, Eneko Larrañeta, Ryan F. Donnelly
Publikováno v:
Materials & Design, Vol 224, Iss , Pp 111416- (2022)
The role of microneedle array patches (MAPs) and, in particular, dissolving MAPs in transdermal drug delivery has increased exponentially over the last decade. MAPs are able to form drug depots in the viable skin from where poorly soluble drugs disso
Externí odkaz:
https://doaj.org/article/aee767f140d84c03bf9ac93281758edb
Autor:
Kurtis Moffatt, Ismaiel A. Tekko, Lalitkumar Vora, Fabiana Volpe-Zanutto, Aaron R. J. Hutton, Jessica Mistilis, Courtney Jarrahian, Nima Akhavein, Andrew D. Weber, Helen O. McCarthy, Ryan F. Donnelly
Publikováno v:
Moffatt, K, Tekko, I A, Vora, L, Volpe-Zanutto, F, Hutton, A R J, Mistilis, J, Jarrahian, C, Akhavein, N, Weber, A D, McCarthy, H O & Donnelly, R F 2022, ' Development and evaluation of dissolving microarray patches for co-administered and repeated intradermal delivery of long-acting rilpivirine and cabotegravir nanosuspensions for paediatric HIV antiretroviral therapy ', Pharmaceutical Research . https://doi.org/10.1007/s11095-022-03408-6
Purpose Whilst significant progress has been made to defeat HIV infection, the efficacy of antiretroviral (ARV) therapy in the paediatric population is often hindered by poor adherence. Currently, two long-acting (LA) intramuscular injectable nanosus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6007ca396343fc9afe60e09ae29de907
https://pure.qub.ac.uk/en/publications/34142e5f-d20d-4de9-9c09-7b9a4944e1bc
https://pure.qub.ac.uk/en/publications/34142e5f-d20d-4de9-9c09-7b9a4944e1bc
Autor:
Kurtis, Moffatt, Ismaiel A, Tekko, Lalitkumar, Vora, Fabiana, Volpe-Zanutto, Aaron R J, Hutton, Jessica, Mistilis, Courtney, Jarrahian, Nima, Akhavein, Andrew D, Weber, Helen O, McCarthy, Ryan F, Donnelly
Publikováno v:
Pharmaceutical research.
Whilst significant progress has been made to defeat HIV infection, the efficacy of antiretroviral (ARV) therapy in the paediatric population is often hindered by poor adherence. Currently, two long-acting (LA) intramuscular injectable nanosuspensions
Publikováno v:
Lab on a chip. 19(12)
A novel method for crystallization utilizing solvent/antisolvent extraction in microfluidic droplet liquid reactors has been developed for rapid and low-cost screening of crystal polymorphism (i.e. molecular crystallographic arrangement or internal s
Publikováno v:
Journal of Microencapsulation. :1-9
Autor:
Glenn T Peer, Gary T. Kinasewitz, Fletcher B. Taylor, Carl W. Oettinger, Nima Akhavein, Martin J. D'Souza
Publikováno v:
Journal of Microencapsulation. 24:337-348
Antisense oligomers to NF-kappaB (ASO) were incorporated into albumin microspheres to determine if microcapsules containing ASO inhibit pro-inflammatory cytokines to a greater extent than comparable doses of ASO in solution. Phagocytosis of microcaps
Autor:
Kimberly Gomes, Grace Allotey-Babington, Sucheta D'Sa, Zhaowei Jin, Naveen Bejugam, Marissa D'Souza, Sanjay Gaikwad, Nima Akhavein, Dinesh Aswani, Wenkai Tong, Nigel D'Souza, Richard Addo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54eeeaac18b7e74ee423ceeac080ed74
https://doi.org/10.1201/b18096-2
https://doi.org/10.1201/b18096-2
Autor:
Katja Behling, Daniel L.J. Thorek, Simone Alidori, Magnus Bergkvist, Michael R. McDevitt, Nima Akhavein, Katia Manova-Todorova, Yevgeniy Romin, Bradley J. Beattie, Dawn Queen, David A. Scheinberg
Publikováno v:
Journal of Urology. 196:1313-1314
RNA interference has tremendous yet unrealized potential to treat a wide range of illnesses. Innovative solutions are needed to protect and selectively deliver small interfering RNA (siRNA) cargo to and within a target cell to fully exploit siRNA as
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 29(38)
SAMs formed from mixtures of alkyne-silanes and alkane-silanes are used to control the areal density of click-reactive alkyne groups on the surface of flat germanium substrates, silicon wafers, and silica nanoparticles. Two new analytical tools are d