Zobrazeno 1 - 10 of 43 pro vyhledávání: '"Nilva K, Cervigne"'
2
Akademický článek
Polypodium leucotomos targets multiple aspects of oral carcinogenesis and it is a potential antitumor phytotherapy against tongue cancer growth
Autor: Pammela A. Lacerda, Luan C. Oenning, Guilherme Cuoghi Bellato, Lucilene Lopes-Santos, Natalícia de Jesus Antunes, Bruno Augusto Linhares Almeida Mariz, Gabriela Teixeira, Rafael Vasconcelos, Gustavo Ferreira Simões, Ivani Aparecida de Souza, Clóvis Antônio Lopes Pinto, Tuula Salo, Ricardo D. Coletta, Taize M. Augusto, Carine Ervolino de Oliveira, Nilva K. Cervigne
Publikováno v: Frontiers in Pharmacology, Vol 13 (2023)
Introduction: Oral cancer refers to malignant tumors, of which 90% are squamous cell carcinomas (OSCCs). These malignancies exhibit rapid progression, poor prognosis, and often mutilating therapeutical approaches. The determination of a prophylactic
Externí odkaz: https://doaj.org/article/3ded6523d37b43989e102f13404dd962
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3
Akademický článek
Heparanase 1 Upregulation Promotes Tumor Progression and Is a Predictor of Low Survival for Oral Cancer
Autor: André A. Nimtz Rodrigues, Lucilene Lopes-Santos, Pammela A. Lacerda, Mariana F. Juste, Bruno Augusto Mariz, Débora C. Cajazeiro, Victoria Giacobbe, Rafael Borges, André Casarim, Giovanna De Sanctis Callegari, Fernando Antônio M. Claret Arcadipane, Ivan Aprahamian, Tuula Anneli Salo, Carine Ervolino De Oliveira, Ricardo D. Coletta, Taize M. Augusto, Nilva K. Cervigne
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Oral cavity cancer is still an important public health problem throughout the world. Oral squamous cell carcinomas (OSCCs) can be quite aggressive and metastatic, with a low survival rate and poor prognosis. However, this is usually relat
Externí odkaz: https://doaj.org/article/b0652a39da7543c78612b70ed68a4ae6
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4
Akademický článek
Extracellular vesicles derived from cancer-associated fibroblasts induce the migration and invasion of oral squamous cell carcinoma
Autor: Mauricio Rocha Dourado, Johanna Korvala, Pirjo Åström, Carine Ervolino De Oliveira, Nilva K. Cervigne, Luciana Souto Mofatto, Debora Campanella Bastos, Ana Camila Pereira Messetti, Edgard Graner, Adriana Franco Paes Leme, Ricardo D. Coletta, Tuula Salo
Publikováno v: Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
As one of the most abundant constituents of the tumour microenvironment (TME), cancer-associated fibroblasts (CAF) display critical roles during tumour progression and metastasis. Multiple classes of molecules including growth factors, cytokines, pro
Externí odkaz: https://doaj.org/article/cf16c292469e401288fee3fbf2baf47f
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7
Akademický článek
Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis.
Autor: Andreia Bufalino, Nilva K Cervigne, Carine Ervolino de Oliveira, Felipe Paiva Fonseca, Priscila Campioni Rodrigues, Carolina Carneiro Soares Macedo, Lays Martin Sobral, Marcia Costa Miguel, Marcio Ajudarte Lopes, Adriana Franco Paes Leme, Daniel W Lambert, Tuula A Salo, Luiz Paulo Kowalski, Edgard Graner, Ricardo D Coletta
Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0136599 (2015)
Deregulated expression of activin A is reported in several tumors, but its biological functions in oral squamous cell carcinoma (OSCC) are unknown. Here, we investigate whether activin A can play a causal role in OSCCs. Activin A expression was asses
Externí odkaz: https://doaj.org/article/37f3ac3ffecf4ed7a7a49507ee684d09
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9
Akademický článek
Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma.
Autor: Rebeca Kawahara, Daniela C Granato, Carolina M Carnielli, Nilva K Cervigne, Carine E Oliveria, César Rivera, Sami Yokoo, Felipe P Fonseca, Marcio Lopes, Alan R Santos-Silva, Edgard Graner, Ricardo D Coletta, Adriana Franco Paes Leme
Publikováno v: PLoS ONE, Vol 9, Iss 12, p e115004 (2014)
Oral squamous cell carcinoma is the most common type of cancer in the oral cavity, representing more than 90% of all oral cancers. The characterization of altered molecules in oral cancer is essential to understand molecular mechanisms underlying tum
Externí odkaz: https://doaj.org/article/89b4b0faf930444c98a96b911fc8386c
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10
Akademický článek
Integrated proteomics identified up-regulated focal adhesion-mediated proteins in human squamous cell carcinoma in an orthotopic murine model.
Autor: Daniela C Granato, Mariana R Zanetti, Rebeca Kawahara, Sami Yokoo, Romênia R Domingues, Annelize Z Aragão, Michelle Agostini, Marcelo F Carazzolle, Ramon O Vidal, Isadora L Flores, Johanna Korvala, Nilva K Cervigne, Alan R S Silva, Ricardo D Coletta, Edgard Graner, Nicholas E Sherman, Adriana F Paes Leme
Publikováno v: PLoS ONE, Vol 9, Iss 5, p e98208 (2014)
Understanding the molecular mechanisms of oral carcinogenesis will yield important advances in diagnostics, prognostics, effective treatment, and outcome of oral cancer. Hence, in this study we have investigated the proteomic and peptidomic profiles
Externí odkaz: https://doaj.org/article/c265446ab5814a659b4cbd0f9f9771f2
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Plný text Recenzováno Digitální knihovna AV ČR
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