Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Nilufer Ertekin‐Taner"'
Autor:
Rebecca R. Valentino, Chloe Ramnarine, Michael G. Heckman, Patrick W. Johnson, Alexandra I. Soto-Beasley, Ronald L. Walton, Shunsuke Koga, Koji Kasanuki, Melissa E. Murray, Ryan J. Uitti, Julie A. Fields, Hugo Botha, Vijay K. Ramanan, Kejal Kantarci, Val J. Lowe, Clifford R. Jack, Nilufer Ertekin-Taner, Rodolfo Savica, Jonathan Graff-Radford, Ronald C. Petersen, Joseph E. Parisi, R. Ross Reichard, Neill R. Graff-Radford, Tanis J. Ferman, Bradley F. Boeve, Zbigniew K. Wszolek, Dennis W. Dickson, Owen A. Ross
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Dementia with Lewy bodies (DLB) is clinically diagnosed when patients develop dementia less than a year after parkinsonism onset. Age is the primary risk factor for DLB and mitochondrial health influences ageing through effective oxidative p
Externí odkaz:
https://doaj.org/article/3ccebbf408344276a4d599bfa2266e82
Autor:
Keith A. Josephs, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Edythe A. Strand, Mary M. Machulda, Hugo Botha, Peter R. Martin, Nha Trang Thu Pham, Julie Stierwalt, Farwa Ali, Marina Buciuc, Matthew Baker, Cristhoper H. Fernandez De Castro, Anthony J. Spychalla, Christopher G. Schwarz, Robert I. Reid, Matthew L. Senjem, Clifford R. Jack, Val J. Lowe, Eileen H. Bigio, Ross R. Reichard, Eric. J. Polley, Nilufer Ertekin-Taner, Rosa Rademakers, Michael A. DeTure, Owen A. Ross, Dennis W. Dickson, Jennifer L. Whitwell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Progressive apraxia of speech (PAOS) is a neurodegenerative syndrome of multiple etiologies which affects spoken communication. Here, the authors characterized the molecular pathology, biochemistry, genetics and longitudinal neuroimaging of 32 autops
Externí odkaz:
https://doaj.org/article/ed3e8ba520e446b7a84a4834659451e7
Autor:
Keith A. Josephs, Nirubol Tosakulwong, Jonathan Graff‐Radford, Stephen D. Weigand, Marina Buciuc, Mary M. Machulda, David T. Jones, Christopher G. Schwarz, Matthew L. Senjem, Nilufer Ertekin‐Taner, Kejal Kantarci, Bradley F. Boeve, David S. Knopman, Clifford R. Jack Jr, Ronald C. Petersen, Val J. Lowe, Jennifer L. Whitwell
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 5, Pp 707-721 (2020)
Abstract Objective To assess the relationships between MRI volumetry and [18F]flortaucipir PET of typical and atypical clinical phenotypes of Alzheimer’s disease, by genarian (age by decade). Methods Five‐hundred and sixty‐four participants inc
Externí odkaz:
https://doaj.org/article/22a5396855af451d927648451c1a092c
Autor:
Mark T. W. Ebbert, Tanner D. Jensen, Karen Jansen-West, Jonathon P. Sens, Joseph S. Reddy, Perry G. Ridge, John S. K. Kauwe, Veronique Belzil, Luc Pregent, Minerva M. Carrasquillo, Dirk Keene, Eric Larson, Paul Crane, Yan W. Asmann, Nilufer Ertekin-Taner, Steven G. Younkin, Owen A. Ross, Rosa Rademakers, Leonard Petrucelli, John D. Fryer
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-23 (2019)
Abstract Background The human genome contains “dark” gene regions that cannot be adequately assembled or aligned using standard short-read sequencing technologies, preventing researchers from identifying mutations within these gene regions that m
Externí odkaz:
https://doaj.org/article/e1a9587d951a4a8790ff8810d11b99d5
Autor:
Denis A Baird, Jimmy Z Liu, Jie Zheng, Solveig K Sieberts, Thanneer Perumal, Benjamin Elsworth, Tom G Richardson, Chia-Yen Chen, Minerva M Carrasquillo, Mariet Allen, Joseph S Reddy, Philip L De Jager, Nilufer Ertekin-Taner, Lara M Mangravite, Ben Logsdon, Karol Estrada, Philip C Haycock, Gibran Hemani, Heiko Runz, George Davey Smith, Tom R Gaunt, AMP-AD eQTL working group
Publikováno v:
PLoS Genetics, Vol 17, Iss 1, p e1009224 (2021)
Discovering drugs that efficiently treat brain diseases has been challenging. Genetic variants that modulate the expression of potential drug targets can be utilized to assess the efficacy of therapeutic interventions. We therefore employed Mendelian
Externí odkaz:
https://doaj.org/article/babae9ca2db7499a9961a514ab39539e
Autor:
Minerva M Carrasquillo, Olivia Belbin, Fanggeng Zou, Mariet Allen, Nilufer Ertekin-Taner, Morad Ansari, Samantha L Wilcox, Mariah R Kashino, Li Ma, Linda H Younkin, Samuel G Younkin, Curtis S Younkin, Toros A Dincman, Melissa E Howard, Chanley C Howell, Chloe M Stanton, Christopher M Watson, Michael Crump, Veronique Vitart, Caroline Hayward, Nicholas D Hastie, Igor Rudan, Harry Campbell, Ozren Polasek, Kristelle Brown, Peter Passmore, David Craig, Bernadette McGuinness, Stephen Todd, Patrick G Kehoe, David M Mann, A David Smith, Helen Beaumont, Donald Warden, Clive Holmes, Reinhard Heun, Heike Kölsch, Noor Kalsheker, V Shane Pankratz, Dennis W Dickson, Neill R Graff-Radford, Ronald C Petersen, Alan F Wright, Steven G Younkin, Kevin Morgan
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8764 (2010)
BACKGROUND:The insulin-degrading enzyme gene (IDE) is a strong functional and positional candidate for late onset Alzheimer's disease (LOAD). METHODOLOGY/PRINCIPAL FINDINGS:We examined conserved regions of IDE and its 10 kb flanks in 269 AD cases and
Externí odkaz:
https://doaj.org/article/30705a34921a465983afe4754bf3908f
Autor:
Carling G. Robinson, Joseph R. Duffy, Heather A. Clark, Rene L. Utianski, Mary M. Machulda, Hugo Botha, Neha Atulkumar Singh, Nha Trang Thu Pham, Nilufer Ertekin‐Taner, Dennis W. Dickson, Val J. Lowe, Jennifer L. Whitwell, Keith A. Josephs
Publikováno v:
European Journal of Neurology. 30:1209-1219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f03fb82996d1759a1e30fc0d7851ac56
https://doi.org/10.1111/ene.15764
https://doi.org/10.1111/ene.15764
Autor:
Neha Atulkumar Singh, Jonathan Graff-Radford, Mary M. Machulda, Christopher G. Schwarz, Matthew C. Baker, Rosa Rademakers, Nilufer Ertekin-Taner, Val J. Lowe, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
J Neurol
Posterior cortical atrophy (PCA) and logopenic progressive aphasia (LPA) are clinical syndromes that commonly have underlying Alzheimer’s disease (AD), although non-AD pathologies have also been reported. PET imaging allows for identification of be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b978ad1d5b0c1a335186f0348a31ce3
https://doi.org/10.1007/s00415-022-11330-5
https://doi.org/10.1007/s00415-022-11330-5
Autor:
Carling Robinson, Joseph Duffy, Heather Clark, Rene Utianski, Mary Machulda, Hugo Botha, Neha Atulkumar Singh, Nha Trang Thu Pham, Peter Martin, Nilufer Ertekin-Taner, Dennis Dickson, Val Lowe, Jennifer Whitwell, Keith Josephs
Publikováno v:
Sunday, April 23.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72bcc75345760ae63edff1a954d16ec2
https://doi.org/10.1212/wnl.0000000000202410
https://doi.org/10.1212/wnl.0000000000202410
Autor:
Neha Atulkumar Singh, Peter R. Martin, Jonathan Graff‐Radford, Mary M. Machulda, Minerva M. Carrasquillo, Nilufer Ertekin‐Taner, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
Alzheimer's & Dementia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0790bddf94a8868c2de80acaf8533544
https://doi.org/10.1002/alz.13059
https://doi.org/10.1002/alz.13059