Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in mice.

Autor: Alberto Anastacio Amarilla, Marcilio Jorge Fumagalli, Mario Luis Figueiredo, Djalma S Lima-Junior, Nilton Nascimento Santos-Junior, Helda Liz Alfonso, Veronica Lippi, Amanda Cristina Trabuco, Flavio Lauretti, Vanessa Danielle Muller, David F Colón, João P M Luiz, Andreas Suhrbier, Yin Xiang Setoh, Alexander A Khromykh, Luiz Tadeu Moraes Figueiredo, Victor Hugo Aquino

Publikováno v: PLoS ONE, Vol 13, Iss 6, p e0199071 (2018)

Rocio virus (ROCV) was the causative agent of an unprecedented outbreak of encephalitis during the 1970s in the Vale do Ribeira, Sao Paulo State, in the Southeast region of Brazil. Surprisingly, no further cases of ROCV infection were identified afte

Externí odkaz: https://doaj.org/article/221bfa8e9d0a47deb9c80d160572561c

Microglial Activation Modulates Neuroendocrine Secretion During Experimental Sepsis

Autor: Maria José Alves da Rocha, Carlos Henrique Rocha Catalão, Luís Henrique Angenendt da Costa, Nilton Nascimento Santos-Junior

Publikováno v: Molecular Neurobiology. 58:2133-2144

Sepsis promotes an inflammatory state in the central nervous system (CNS) that may cause autonomic, cognitive, and endocrine changes. Microglia, a resident immune cell of the CNS, is activated in several brain regions during sepsis, suggesting its pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def8c9e3ee2f388e2a5cd1f2e75bc5c8
https://doi.org/10.1007/s12035-020-02241-5

Cardiovascular and autonomic dysfunction in murine ligature-induced periodontitis

Autor: Sandra Y. Fukada, Nilton Nascimento Santos-Junior, Helio Cesar Salgado, João Paulo Mesquita Luiz, Aline Barbosa Ribeiro, Alexandre Kanashiro, Mauro de Oliveira, Rubens Fazan Júnior, Thaise Mayumi Taira, José C. Alves-Filho

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)

The present study examined the hemodynamics [arterial pressure (AP), AP variability (APV), heart rate (HR), and heart rate variability (HRV)], cardiac function (echocardiographycally), and myocardial inflammation in Balb/c mice submitted to Periodont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaafaf35c90ebc049ae123246e1e6861

CCR2 plays a protective role in rocio virus–induced encephalitis by promoting macrophage infiltration into the brain

Autor: Naphak Modhiran, Mario Luis Garcia de Figueiredo, Victor Hugo Aquino, David F. Colón, Silvia Elena Sánchez Mendoza, Leonardo J. Galvão-Lima, Amanda C. Desiderá, Alexander A. Khromykh, Cleide Lúcia Araújo Silva, Helda Liz Alfonso, Richard L Spinieli, Nilton Nascimento Santos-Junior, Yin Xiang Setoh, Djalma S. Lima-Junior, Amanda Cristina Trabuco, João Paulo Mesquita Luiz, Sandra L. Balero Penharvel Martins, Nias Y. G. Peng, Luiz Tadeu Moraes Figueiredo, Eduardo Magalhães Rego, Veronica Lippi, Flávio Lauretti, Alberto A. Amarilla, Fernando Q. Cunha, Gabriel Shimizu Bassi, José C. Alves-Filho, Wilson Gómez Manrique, Christie Ramos Andrade Leite-Panissi, Marcílio Jorge Fumagalli

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The Journal of Infectious Diseases

Rocio virus (ROCV) is a highly neuropathogenic mosquito-transmitted flavivirus responsible for an unprecedented outbreak of human encephalitis during 1975–1976 in Sao Paulo State, Brazil. Previous studies have shown an increased number of inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6389b357cd773f38547270c8616a15

Neuroprotective action of Eicosapentaenoic (EPA) and Docosahexaenoic (DHA) acids on Paraquat intoxication in Drosophila melanogaster

Autor: Anderson de Oliveira Souza, Carlos Henrique Rocha Catalão, Nilton Nascimento Santos-Junior, Maria José Alves da Rocha, Júlia Fernanda dos Santos, Luciane C. Alberici, Carlos Antonio Couto-Lima

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Several studies have shown the protective effects of dietary enrichment of omega-3 (ω-3) long-chain fatty acids in several animal models of neurodegenerative diseases. Here we investigate if eicosapentaenoic (EPA) and Docosahexaenoic (DHA) acids (ω

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54bc255eef5e6064199d380c72418045
https://pubmed.ncbi.nlm.nih.gov/30502405