In Utero Exposure to Environmental Tobacco Smoke Increases Neuroinflammation in Offspring

Autor: Ana Carolina Cardoso dos Santos Durão, Wesley Nogueira Brandão, Vitor Bruno, Lídia Emmanuela W. Spelta, Stephanie de Oliveira Duro, Nilton Barreto dos Santos, Beatriz Aparecida Passos Bismara Paranhos, Nágela Ghabdan Zanluqui, Maurício Yonamine, Jean Pierre Schatzmann Peron, Carolina Demarchi Munhoz, Tania Marcourakis

Publikováno v: Frontiers in Toxicology, Vol 3 (2022)

The embryonic stage is the most vulnerable period for congenital abnormalities. Due to its prolonged developmental course, the central nervous system (CNS) is susceptible to numerous genetic, epigenetic, and environmental influences. During embryo im

Externí odkaz: https://doaj.org/article/6204e2d4d552483d984fd067cb5ac0da

The resilience of adolescent male rats to acute stress-induced delayed anxiety is age-related and glucocorticoid release-dependent

Autor: Rodrigo Campos-Cardoso, Leonardo Santana Novaes, Lívea Dornela Godoy, Nilton Barreto dos Santos, Juliano Genaro Perfetto, Willian Lazarini-Lopes, Norberto Garcia-Cairasco, Cláudia Maria Padovan, Carolina Demarchi Munhoz

Publikováno v: Campos-Cardoso, R, Novaes, L S, Godoy, L D, Dos Santos, N B, Perfetto, J G, Lazarini-Lopes, W, Garcia-Cairasco, N, Padovan, C M & Munhoz, C D 2023, ' The resilience of adolescent male rats to acute stress-induced delayed anxiety is age-related and glucocorticoid release-dependent ', Neuropharmacology, vol. 226, 109385, pp. 109385 . https://doi.org/10.1016/j.neuropharm.2022.109385
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Studies investigated how stressful experiences modulate physiological and behavioral responses and the consequences of stress-induced corticosterone release in anxiety-like behavior. Adolescence is crucial to brain maturation, and several neurobiolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6caea38cca8c54abbb4d8ae0d78c2b5
https://pure.au.dk/portal/da/publications/the-resilience-of-adolescent-male-rats-to-acute-stressinduced-delayed-anxiety-is-agerelated-and-glucocorticoid-releasedependent(80fa0e4b-4023-427b-a954-17850fcde144).html

AHR is a Zika virus host factor and a candidate target for antiviral therapy

Autor: Leonardo Romorini, Carolina Demarchi Munhoz, Zhongyan Wang, Francisco J. Quintana, Seyed Mohamad Sadegh Modaresi, Cristina Gutiérrez-Vázquez, Jean Pierre Schatzmann Peron, Lee Gehrke, María S. Rodriguez Varela, Nágela Ghabdan Zanluqui, Andreia Barroso, Cybele C. García, Carolina Manganeli Polonio, Irene Bosch, Zhaorong Li, Veit Rothhammer, Federico Giovannoni, Emily C. Tjon, David H. Sherr, Liliana Maria Sanmarco, Nilton Barreto dos Santos, Maria Florencia Torti, Elsa B. Damonte, Michael A. Wheeler, Maisa C. Takenaka

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nat Neurosci

Zika virus (ZIKV) is a flavivirus linked to multiple birth defects including microcephaly, known as congenital ZIKV syndrome. The identification of host factors involved in ZIKV replication may guide efficacious therapeutic interventions. In genome-w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e4af53499bb8671d621c9dd2a4438d
https://doi.org/10.1038/s41593-020-0664-0

SARS-CoV-2 Infection Impacts Carbon Metabolism and Depends on Glutamine for Replication in Syrian Hamster Astrocytes

Autor: Lilian Gomes de Oliveira, Yan de Souza Angelo, Pedro Yamamoto, Victor Corasolla Carregari, Fernanda Crunfi, Guilherme Reis-de-Oliveira, Lícia Costa, Érica Almeida Duque, Nilton Barreto dos Santos, Glaucia Maria Almeida, Egidi Mayara Firmino, Isadora Marques Paiva, Carolina Manganeli Polonio, Nagela Ghabdan Zanluqui, Marília Garcia de Oliveira, Gustavo Gastão Davanzo, Marina Caçador Ayupe, Caio Loureiro Salgado, Antônio Francisco de Souza Filho, Marcelo Valdemir de Araújo, Taiana Tainá Silva-Pereira, Angélica Cristine de Almeida Campos, Luiz Gustavo Bentim Góes, Marielton dos Passos Cunha, Maria Regina D’Império Lima, Denise Morais Fonseca, Ana Márcia de Sá Guimarães, Paola Camargo Minoprio, Carolina Demarchi Munhoz, Cláudia Madalena Cabrera Mori, Pedro Manoel Moraes-Vieira, Thiago Mattar Cunha, Daniel Martins-de-Souza, Jean Pierre Schatzmann Peron

Coronaviruses belong to a well-known family of enveloped RNA viruses and are the causative agent of the common cold. Although the seasonal coronaviruses do not pose a threat to human life, three members of this family, i.e., SARS-CoV, MERS-CoV and re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb09be1a80088de41613d29f6695cac0
https://doi.org/10.1101/2021.10.23.465567

Norepinephrine and glucocorticoids modulate chronic unpredictable stress-induced increase in the Type 2 CRF and glucocorticoid receptors in brain structures related to the HPA Axis activation

Autor: Joelcimar Martins, Jackson C. Bittencourt, M. B. Malta, Carolina Demarchi Munhoz, Rosana Camarini, Cristoforo Scavone, Luciane V. Sita, Leonardo S. Novaes, Nilton Barreto dos Santos

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

The stress response is multifactorial and enrolls circuitries to build a coordinated reaction, leading to behavioral, endocrine, and autonomic changes. These changes are mainly related to the hypothalamus-pituitary-adrenal (HPA) axis activation and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c9332b38aaafdfe22b57ca07c4cf17