Effects of anterior cingulate cortex lesions on a continuous performance task for mice

Autor: Hvoslef-Eide, Martha, Nilsson, Simon Ro, Hailwood, Jonathan M, Robbins, Trevor W, Saksida, Lisa M, Mar, Adam C, Bussey, Timothy J

Important tools in the study of prefrontal cortical-dependent executive functions are cross-species behavioural tasks with translational validity. A widely used test of executive function and attention in humans is the continuous performance task (CP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a8ca22842084dae0a88b03ef6f2688

Dopamine D2-like receptor stimulation blocks negative feedback in visual and spatial reversal learning in the rat: behavioural and computational evidence

Autor: Alsiö, Johan, Phillips, Benjamin U, Sala-Bayo, Júlia, Nilsson, Simon RO, Calafat-Pla, Teresa C, Rizwand, Arazo, Plumbridge, Jessica M, López-Cruz, Laura, Dalley, Jeffrey W, Cardinal, Rudolf N, Mar, Adam C, Robbins, Trevor W

RATIONALE: Dopamine D2-like receptors (D2R) are important drug targets in schizophrenia and Parkinson's disease, but D2R ligands also cause cognitive inflexibility such as poor reversal learning. The specific role of D2R in reversal learning remains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa087c04c2754f8aa71051bd93f79e2a

Effects of anterior cingulate cortex lesions on a continuous performance task for mice.

Autor: Hvoslef-Eide M; Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, UK.; MRC and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, UK.; Department of Biosciences, University of Oslo, PO Box 1066, Blindern, 0371 Oslo, Norway., Nilsson SR; Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, UK.; MRC and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, UK.; Neuroscience Institute, New York University Medical Center, New York, NY, USA.; Department of Neuroscience and Physiology, New York University Medical Center, New York, NY, USA., Hailwood JM; Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, UK.; MRC and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, UK., Robbins TW; Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, UK.; MRC and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, UK., Saksida LM; Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, UK.; MRC and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, UK.; Molecular Medicine Research Group, Robarts Research Institute & Department of Physiology, Western University, London, ON, Canada.; Pharmacology, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.; The Brain and Mind Institute, Western University, London, ON, Canada., Mar AC; Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, UK.; MRC and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, UK.; Neuroscience Institute, New York University Medical Center, New York, NY, USA.; Department of Neuroscience and Physiology, New York University Medical Center, New York, NY, USA., Bussey TJ; Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, UK.; MRC and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, UK.; Molecular Medicine Research Group, Robarts Research Institute & Department of Physiology, Western University, London, ON, Canada.; Pharmacology, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.; The Brain and Mind Institute, Western University, London, ON, Canada.

Publikováno v: Brain and neuroscience advances [Brain Neurosci Adv] 2018 Jan; Vol. 2. Date of Electronic Publication: 2018 May 29.