Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Nils Wiedemann"'
Publikováno v:
FEBS Open Bio, Vol 14, Iss 10, Pp 1595-1609 (2024)
β‐barrel membrane proteins in the mitochondrial outer membrane are crucial for mediating the metabolite exchange between the cytosol and the mitochondrial intermembrane space. In addition, the β‐barrel membrane protein subunit Tom40 of the tran
Externí odkaz:
https://doaj.org/article/93c94b4b56fa4f359fa68338243a6d40
Autor:
Heike Rampelt, Iva Sucec, Beate Bersch, Patrick Horten, Inge Perschil, Jean-Claude Martinou, Martin van der Laan, Nils Wiedemann, Paul Schanda, Nikolaus Pfanner
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background The mitochondrial pyruvate carrier (MPC) plays a central role in energy metabolism by transporting pyruvate across the inner mitochondrial membrane. Its heterodimeric composition and homology to SWEET and semiSWEET transporters se
Externí odkaz:
https://doaj.org/article/b7ca500a447d438abd73801cf1639dc7
Autor:
Marcel Morgenstern, Sebastian B. Stiller, Philipp Lübbert, Christian D. Peikert, Stefan Dannenmaier, Friedel Drepper, Uri Weill, Philipp Höß, Reinhild Feuerstein, Michael Gebert, Maria Bohnert, Martin van der Laan, Maya Schuldiner, Conny Schütze, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Publikováno v:
Cell Reports, Vol 19, Iss 13, Pp 2836-2852 (2017)
Mitochondria perform central functions in cellular bioenergetics, metabolism, and signaling, and their dysfunction has been linked to numerous diseases. The available studies cover only part of the mitochondrial proteome, and a separation of core mit
Externí odkaz:
https://doaj.org/article/afe2beb6dfb24cbab29ea223b1e61717
Autor:
Lars Ellenrieder, Łukasz Opaliński, Lars Becker, Vivien Krüger, Oliver Mirus, Sebastian P. Straub, Katharina Ebell, Nadine Flinner, Sebastian B. Stiller, Bernard Guiard, Chris Meisinger, Nils Wiedemann, Enrico Schleiff, Richard Wagner, Nikolaus Pfanner, Thomas Becker
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The protein Mdm10 is known to be present in the endoplasmic reticulum-mitochondria encounter structure (ERMES) and in mitochondrial sorting and assembly machinery (SAM). Here, the authors examine how this protein interacts with SAM and EMRES, showing
Externí odkaz:
https://doaj.org/article/9bf2b01669244292939e16b34fde2489
Autor:
Alexis Hofherr, Claudia Seger, Fiona Fitzpatrick, Tilman Busch, Elisabeth Michel, Jingting Luan, Lea Osterried, Frieder Linden, Albrecht Kramer-Zucker, Barbara Wakimoto, Conny Schütze, Nils Wiedemann, Anna Artati, Jerzy Adamski, Gerd Walz, Edmund R S Kunji, Craig Montell, Terry Watnick, Michael Köttgen
Publikováno v:
PLoS Biology, Vol 16, Iss 8, p e2005651 (2018)
Cilia are organelles specialized in movement and signal transduction. The ciliary transient receptor potential ion channel polycystin-2 (TRPP2) controls elementary cilia-mediated physiological functions ranging from male fertility and kidney developm
Externí odkaz:
https://doaj.org/article/fb76b96ee34346ac93852c1d9cd88af5
Publikováno v:
Metabolites, Vol 9, Iss 11, p 266 (2019)
Yeast cells respond to heat stress by remodeling their gene expression, resulting in the changes of the corresponding proteins and metabolites. Compared to the intensively investigated transcriptome and proteome, the metabolic response to heat stress
Externí odkaz:
https://doaj.org/article/24c2809632994b33904f127cd884deec
Autor:
Yael Elbaz-Alon, Michal Eisenberg-Bord, Vera Shinder, Sebastian Berthold Stiller, Eyal Shimoni, Nils Wiedemann, Tamar Geiger, Maya Schuldiner
Publikováno v:
Cell Reports, Vol 12, Iss 1, Pp 7-14 (2015)
Communication between organelles is crucial for eukaryotic cells to function as one coherent unit. An important means of communication is through membrane contact sites, where two organelles come into close proximity allowing the transport of lipids
Externí odkaz:
https://doaj.org/article/9b63551d194c46829252fcee8ae16d89
Publikováno v:
Molecular Cell. 83:890-910
Autor:
Uwe Schulte, Fabian den Brave, Alexander Haupt, Arushi Gupta, Jiyao Song, Catrin S. Müller, Jeannine Engelke, Swadha Mishra, Christoph Mårtensson, Lars Ellenrieder, Chantal Priesnitz, Sebastian P. Straub, Kim Nguyen Doan, Bogusz Kulawiak, Wolfgang Bildl, Heike Rampelt, Nils Wiedemann, Nikolaus Pfanner, Bernd Fakler, Thomas Becker
Publikováno v:
Nature. 614:153-159
Mitochondria have crucial roles in cellular energetics, metabolism, signalling and quality control1–4. They contain around 1,000 different proteins that often assemble into complexes and supercomplexes such as respiratory complexes and preprotein t
Autor:
Hironori Takeda, Jon V. Busto, Caroline Lindau, Akihisa Tsutsumi, Kentaro Tomii, Kenichiro Imai, Yu Yamamori, Takatsugu Hirokawa, Chie Motono, Iniyan Ganesan, Lena-Sophie Wenz, Thomas Becker, Masahide Kikkawa, Nikolaus Pfanner, Nils Wiedemann, Toshiya Endo
Publikováno v:
Nature Structural & Molecular Biology. 30:176-187
Mitochondrial β-barrel proteins are essential for the transport of metabolites, ions and proteins. The sorting and assembly machinery (SAM) mediates their folding and membrane insertion. We report the cryo-electron microscopy structure of the yeast