Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nils Schmerer"'
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The classic understanding of molecular disease-mechanisms is largely based on protein-centric models. During the past decade however, genetic studies have identified numerous disease-loci in the human genome that do not encode proteins. Such non-codi
Externí odkaz:
https://doaj.org/article/1adb40d6aafa43ea848deebb60de82d6
Autor:
Alexander Visekruna, Ulrich Steinhoff, Markus Bosmann, Bernd Schmeck, Wilhelm Bertrams, Leon N. Schulte, Nils Schmerer, Arjun Sharma, Hans-Joachim Mollenkopf, Aleksandra Lopez Krol, Daniel Staudenraus, Maik Luu, Hanna Leister
Apart from the constitutive proteasome, the immunoproteasome that comprises the three proteolytic subunits LMP2, MECL-1, and LMP7 is expressed in most immune cells. In this study, we describe opposing roles for immunoproteasomes in regulating the tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5cc6c0bfb1239e3c0ef9c613c33c00
https://doi.org/10.1158/2326-6066.c.6550153.v1
https://doi.org/10.1158/2326-6066.c.6550153.v1
Autor:
Alexander Visekruna, Ulrich Steinhoff, Markus Bosmann, Bernd Schmeck, Wilhelm Bertrams, Leon N. Schulte, Nils Schmerer, Arjun Sharma, Hans-Joachim Mollenkopf, Aleksandra Lopez Krol, Daniel Staudenraus, Maik Luu, Hanna Leister
Supplementary Figures 1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e79165f16ec57e3632c2ad4a331fb88
https://doi.org/10.1158/2326-6066.22543144
https://doi.org/10.1158/2326-6066.22543144
Autor:
Marina Aznaourova, Nils Schmerer, Harshavardhan Janga, Zhenhua Zhang, Kim Pauck, Judith Bushe, Sarah M. Volkers, Daniel Wendisch, Philipp Georg, Evgenia Ntini, Michelle Aillaud, Margrit Gündisch, Elisabeth Mack, Chrysanthi Skevaki, Christian Keller, Christian Bauer, Wilhelm Bertrams, Annalisa Marsico, Andrea Nist, Thorsten Stiewe, Achim D. Gruber, Clemens Ruppert, Yang Li, Holger Garn, Leif E. Sander, Bernd Schmeck, Leon N. Schulte
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 119(36):e2120680119. NATL ACAD SCIENCES
Proc. Natl. Acad. Sci. U.S.A. 119:e2120680119 (2022)
Proceedings of the National Academy of Sciences of the United States of America, 119(36):e2120680119. NATL ACAD SCIENCES
Proc. Natl. Acad. Sci. U.S.A. 119:e2120680119 (2022)
The systemic immune response to viral infection is shaped by master transcription factors, such as NF-κB, STAT1, or PU.1. Although long noncoding RNAs (lncRNAs) have been suggested as important regulators of transcription factor activity, their cont
Autor:
Hanna Leister, Ulrich Steinhoff, Bernd Schmeck, Maik Luu, Leon N. Schulte, Markus Bosmann, Hans-Joachim Mollenkopf, Daniel Staudenraus, Alexander Visekruna, Wilhelm Bertrams, Aleksandra Lopez Krol, Nils Schmerer, Arjun Sharma
Publikováno v:
Cancer Immunol Res
Apart from the constitutive proteasome, the immunoproteasome that comprises the three proteolytic subunits LMP2, MECL-1, and LMP7 is expressed in most immune cells. In this study, we describe opposing roles for immunoproteasomes in regulating the tum
Autor:
Kim Pauck, Sarah M. Volkers, Leon N. Schulte, Daniel Wendisch, Margrit Guendisch, Yang Li, Judith Hoppe, Christian Keller, Elisabeth Mack, Philipp Georg, Christian Bauer, Andrea Nist, Holger Garn, Wilhelm Bertrams, Harshavardhan Janga, Marina Aznaourova, Leif E. Sander, Chrysanthi Skevaki, Thorsten Stiewe, Achim D. Gruber, Clemens Ruppert, Zhenhua Zhang, Nils Schmerer, Bernd Schmeck
The systemic immune response to viral infection is shaped by master transcription factors such as NFκB or PU.1. Although long non-coding RNAs (lncRNAs) have been suggested as important regulators of transcription factor activity, their contributions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adab11fdddafb03fa3cc4068e0b48372
https://doi.org/10.1101/2021.11.05.467458
https://doi.org/10.1101/2021.11.05.467458
Autor:
Leon Schulte, Nils Schmerer
Publikováno v:
WIREs RNA. 12
Autor:
Nils Schmerer, Leon N. Schulte
Publikováno v:
Wiley interdisciplinary reviews. RNAREFERENCES. 12(6)
Infectious and inflammatory diseases remain major causes of mortality and morbidity worldwide. To combat bacterial infections, the mammalian immune system employs a myriad of regulators, which secure the effective initiation of inflammatory responses
Autor:
Simon Dökel, Stephanie Sefried, Nils Schmerer, Leif E. Sander, Marcus Lechner, Bernd Schmeck, Leon N. Schulte, Marina Aznaourova, Achim D. Gruber, Andreas Kaufmann, Harshavardhan Janga, Sarah M. Volkers, Uwe Linne, Jens Dorna, Philipp Georg, Stefan Bauer, Judith Hoppe
Publikováno v:
Proc Natl Acad Sci U S A
RNA has been proposed as an important scaffolding factor in the nucleus, aiding protein complex assembly in the dense intracellular milieu. Architectural contributions of RNA to cytosolic signaling pathways, however, remain largely unknown. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ddb95003eac84519c0848a4981c58e3
https://europepmc.org/articles/PMC7183186/
https://europepmc.org/articles/PMC7183186/