Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Nils Paust"'
Autor:
Benita Johannsen, Desirée Baumgartner, Michal Karpíšek, David Stejskal, Noémie Boillat-Blanco, José Knüsli, Marcus Panning, Nils Paust, Roland Zengerle, Konstantinos Mitsakakis
Publikováno v:
Biosensors, Vol 13, Iss 12, p 1009 (2023)
C-reactive protein is a well-studied host response biomarker, whose diagnostic performance depends on its accurate classification into concentration zones defined by clinical scenario-specific cutoff values. We validated a newly developed, bead-based
Externí odkaz:
https://doaj.org/article/499cf3b6dd93476c868d2394ca763f99
Autor:
Daniel M. Kainz, Bastian J. Breiner, Susanna M. Früh, Tobias Hutzenlaub, Roland Zengerle, Nils Paust
Publikováno v:
Microsystems & Nanoengineering, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Despite the widespread application of point-of-care lateral flow tests, the viscosity dependence of these assay results remains a significant challenge. Here, we employ centrifugal microfluidic flow control through the nitrocellulose membran
Externí odkaz:
https://doaj.org/article/dd64700eedb14ce7ab3605a5eac347f0
Autor:
Sebastian Hin, Nils Paust, Markus Rombach, Jan Lüddecke, Mara Specht, Roland Zengerle, Konstantinos Mitsakakis
Publikováno v:
Micromachines, Vol 13, Iss 12, p 2112 (2022)
Centrifugal microfluidics enables fully automated molecular diagnostics at the point-of-need. However, the integration of solid-phase nucleic acid extraction remains a challenge. Under this scope, we developed the magnetophoresis under continuous rot
Externí odkaz:
https://doaj.org/article/c03b7567a84247ef9895a7b1bec3d585
Autor:
Benita Johannsen, Desirée Baumgartner, Lena Karkossa, Nils Paust, Michal Karpíšek, Nagihan Bostanci, Roland Zengerle, Konstantinos Mitsakakis
Publikováno v:
Biosensors, Vol 12, Iss 6, p 413 (2022)
In this paper, we present the ImmunoDisk, a fully automated sample-to-answer centrifugal microfluidic cartridge, integrating a heterogeneous, wash-free, magnetic- and fluorescent bead-based immunoassay (bound-free phase detection immunoassay/BFPD-IA)
Externí odkaz:
https://doaj.org/article/cc033274b2274537bdc7b2c015b029aa
Autor:
Sebastian Hin, Benjamin Lopez-Jimena, Mohammed Bakheit, Vanessa Klein, Seamus Stack, Cheikh Fall, Amadou Sall, Khalid Enan, Mohamed Mustafa, Liz Gillies, Viorel Rusu, Sven Goethel, Nils Paust, Roland Zengerle, Sieghard Frischmann, Manfred Weidmann, Konstantinos Mitsakakis
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009177 (2021)
BackgroundIn this work, a platform was developed and tested to allow to detect a variety of candidate viral, bacterial and parasitic pathogens, for acute fever of unknown origin. The platform is based on a centrifugal microfluidic cartridge, the LabD
Externí odkaz:
https://doaj.org/article/bc4d38e4f63249c587951b10be519b90
Autor:
Desirée Baumgartner, Benita Johannsen, Mara Specht, Jan Lüddecke, Markus Rombach, Sebastian Hin, Nils Paust, Felix von Stetten, Roland Zengerle, Christopher Herz, Johannes R. Peham, Pune N. Paqué, Thomas Attin, Joël S. Jenzer, Philipp Körner, Patrick R. Schmidlin, Thomas Thurnheer, Florian J. Wegehaupt, Wendy E. Kaman, Andrew Stubbs, John P. Hays, Viorel Rusu, Alex Michie, Thomas Binsl, David Stejskal, Michal Karpíšek, Kai Bao, Nagihan Bostanci, Georgios N. Belibasakis, Konstantinos Mitsakakis
Publikováno v:
Biosensors, Vol 11, Iss 11, p 423 (2021)
Periodontitis and dental caries are two major bacterially induced, non-communicable diseases that cause the deterioration of oral health, with implications in patients’ general health. Early, precise diagnosis and personalized monitoring are essent
Externí odkaz:
https://doaj.org/article/99cf5461c1914ad484eb0d8614eb3dc2
Autor:
Lisa Becherer, Jacob Friedrich Hess, Sieghard Frischmann, Mohammed Bakheit, Hans Nitschko, Silvina Stinco, Friedrich Zitz, Hannes Hofer, Giampiero Porro, Florian Hausladen, Karl Stock, Dominik Drossart, Holger Wurm, Hanna Kuhn, Dominik Huber, Tobias Hutzenlaub, Nils Paust, Mark Keller, Oliver Strohmeier, Simon Wadle, Nadine Borst, Roland Zengerle, Felix von Stetten
Publikováno v:
Micromachines, Vol 12, Iss 2, p 159 (2021)
This paper presents a universal point-of-care system for fully automated quantification of human T-cell lymphotropic virus type 1 (HTLV-1) proviral load, including genomic RNA, based on digital reverse RNA transcription and c-DNA amplification by MD
Externí odkaz:
https://doaj.org/article/4a5b12acd76d4d2a9e78791e90dfe337
Autor:
Martin Schulz, Sophia Probst, Silvia Calabrese, Ana R. Homann, Nadine Borst, Marian Weiss, Felix von Stetten, Roland Zengerle, Nils Paust
Publikováno v:
Molecules, Vol 25, Iss 8, p 1914 (2020)
We present a versatile tool for the generation of monodisperse water-in-fluorinated-oil droplets in standard reaction tubes by centrifugal step emulsification. The microfluidic cartridge is designed as an insert into a standard 2 mL reaction tube and
Externí odkaz:
https://doaj.org/article/be136a0e990a485aa5a7b1fe6c16cb87
Publikováno v:
Micromachines, Vol 6, Iss 8, Pp 1180-1188 (2015)
The high throughput preparation of emulsions with high internal volume fractions is important for many different applications, e.g., drug delivery. However, most emulsification techniques reach only low internal volume fractions and need stable flow
Externí odkaz:
https://doaj.org/article/c87ea2c14c2a452ab74f83c84c33c485
Publikováno v:
Sensors, Vol 12, Iss 8, Pp 10550-10565 (2012)
In this paper a multi-disciplinary simulation of a capacitive droplet sensor based on an open plate capacitor as transducing element is presented. The numerical simulations are based on the finite volume method (FVM), including calculations of an ele
Externí odkaz:
https://doaj.org/article/0b14438147294c189ea81ad5082ae761