Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nils Ohnesorge"'
Autor:
Mariana Neves, Antonina Klippert, Fanny Knöspel, Juliane Rudeck, Ailine Stolz, Zsofia Ban, Markus Becker, Kai Diederich, Barbara Grune, Pia Kahnau, Nils Ohnesorge, Johannes Pucher, Gilbert Schönfelder, Bettina Bert, Daniel Butzke
Publikováno v:
Journal of Biomedical Semantics, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Current animal protection laws require replacement of animal experiments with alternative methods, whenever such methods are suitable to reach the intended scientific objective. However, searching for alternative methods in the scientific li
Externí odkaz:
https://doaj.org/article/136f4476ca0443fba702bb7a53358b93
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Pain is an unpleasant, negative emotion and its debilitating effects are complex to manage. Mammalian models have long dominated research on nociception and pain, but there is increasing evidence for comparable processes in fish. The need to improve
Externí odkaz:
https://doaj.org/article/dc428f487b5649c080c9f76b421e6f91
Autor:
Sarah M. Wade, Nils Ohnesorge, Hayley McLoughlin, Monika Biniecka, Steven P. Carter, Michelle Trenkman, Clare C. Cunningham, Trudy McGarry, Mary Canavan, Breandán N. Kennedy, Douglas J. Veale, Ursula Fearon
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 402-413 (2019)
Background: Although neoangiogenesis is a hallmark of chronic inflammatory diseases such as inflammatory arthritis and many cancers, therapeutic agents targeting the vasculature remain elusive. Here we identified miR-125a as an important regulator of
Externí odkaz:
https://doaj.org/article/68d5954a96d04b878c687d48d5470037
Autor:
Nils Ohnesorge, Temitope Sasore, Daniel Hillary, Yolanda Alvarez, Michelle Carey, Breandán N. Kennedy
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Unbiased screening of large randomized chemical libraries in vivo is a powerful tool to find new drugs and targets. However, forward chemical screens in zebrafish can be time consuming and usually >99% of test compounds have no significant effect on
Externí odkaz:
https://doaj.org/article/4d017c23d5524fdcb233e2adce076d52
Autor:
Martin Lange, Nils Ohnesorge, Dennis Hoffmann, Susana F. Rocha, Rui Benedito, Arndt F. Siekmann
Publikováno v:
Developmental biology. 486
The formation of appropriately patterned blood vessel networks requires endothelial cell migration and proliferation. Signaling through the Vascular Endothelial Growth Factor A (VEGFA) pathway is instrumental in coordinating these processes. mRNA spl
Autor:
Mary Canavan, Clare C. Cunningham, Monika Biniecka, Hayley McLoughlin, Sarah M. Wade, Nils Ohnesorge, Douglas J. Veale, Steven P. Carter, Michelle Trenkman, Breandán N. Kennedy, Ursula Fearon, Trudy McGarry
Publikováno v:
EBioMedicine
Background Although neoangiogenesis is a hallmark of chronic inflammatory diseases such as inflammatory arthritis and many cancers, therapeutic agents targeting the vasculature remain elusive. Here we identified miR-125a as an important regulator of
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience, Vol 15 (2021)
Pain is an unpleasant, negative emotion and its debilitating effects are complex to manage. Mammalian models have long dominated research on nociception and pain, but there is increasing evidence for comparable processes in fish. The need to improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c47fb0b972cd963e7b40ef0b66824b6
https://refubium.fu-berlin.de/handle/fub188/31090
https://refubium.fu-berlin.de/handle/fub188/31090
Autor:
Nils Ohnesorge, Martin Lange, Elvin Leonard, Dennis Hoffmann, Arndt F. Siekmann, Rui Benedito, Susanna Rocha
SUMMARYThe formation of appropriately patterned blood vessel networks requires endothelial cell migration and proliferation. Signaling through the Vascular Endothelial Growth Factor A (VEGFA) pathway is instrumental in coordinating these processes. m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff957c824236bcc3e856c30a20a6f711
https://doi.org/10.1101/2020.04.01.018796
https://doi.org/10.1101/2020.04.01.018796
Autor:
Mary Canavan, Monika Biniecka, S. Wade, DJ Veale, Nils Ohnesorge, Ursula Fearon, Breandán N. Kennedy, Trudy McGarry, S Merrigan
Publikováno v:
Poster Presentations.
Background Psoriatic arthritis (PsA) is characterised by an early vascular phase which is essential in perpetuating pannus growth, immune responses and disease progression. Recently, numerous studies have highlighted the emerging importance of endoth
Autor:
Nils Ohnesorge, Brendan Kennedy, Ursula Fearon, Sarah M. Wade, Monika Biniecka, Douglas J. Veale, Stephaine Merrigan, Trudy McGarry
Publikováno v:
New players and novel targets in inflammation.
Introduction Psoriatic arthritis (PsA) is characterised by an early vascular phase which is essential in perpetuating pannus growth, immune responses and disease progression. Whilst established therapies, including methotrexate, anti-TNFs and Vitamin