Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nils Kost"'
Autor:
Kyoko Hiragami-Hamada, Szabolcs Soeroes, Miroslav Nikolov, Bryan Wilkins, Sarah Kreuz, Carol Chen, Inti A. De La Rosa-Velázquez, Hans Michael Zenn, Nils Kost, Wiebke Pohl, Aleksandar Chernev, Dirk Schwarzer, Thomas Jenuwein, Matthew Lorincz, Bastian Zimmermann, Peter Jomo Walla, Heinz Neumann, Tuncay Baubec, Henning Urlaub, Wolfgang Fischle
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Heterochromatin protein 1 (HP1), including HP1 α, β and γ, is a family of non-histone chromatin factors thought to be involved in chromatin organization. Here, the authors show that dimeric HP1β interacts dynamically with H3K9me3, a hallmark of h
Externí odkaz:
https://doaj.org/article/daad9f601a9746829955629c5cc1bf39
Autor:
Dinshaw J. Patel, David Soong, Robert G. Roeder, Zhanyun Tang, Nils Kost, Tomoyoshi Nakadai, Olivier Elemento, Zhanxin Wang, Wei Yi Chen, Stephen D. Nimer, Ari Melnick, Xiao-Jian Sun, Lan Wang, Yanwen Jiang, Wolfgang Fischle
Publikováno v:
Nature
A multiprotein complex containing AML1–ETO, the most common fusion protein found in acute myeloid leukaemia, is revealed and analysed in leukaemic cells, and a novel, functionally important protein-binding interface is identified. The fusion protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd59509ca7c2e495320789bd06ed2a34
https://doi.org/10.1038/nature12287
https://doi.org/10.1038/nature12287
Autor:
Tuncay Baubec, Sarah Kreuz, Henning Urlaub, Carol Chen, Matthew C. Lorincz, Dirk Schwarzer, Wiebke H. Pohl, Szabolcs Soeroes, Bastian Zimmermann, Thomas Jenuwein, Miroslav Nikolov, Inti A. De La Rosa-Velázquez, Wolfgang Fischle, Aleksandar Chernev, Peter Walla, Bryan J. Wilkins, Heinz Neumann, Nils Kost, Hans Michael Zenn, Kyoko Hiragami-Hamada
Publikováno v:
Europe PubMed Central
Nature communications
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Nature communications
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Histone H3 trimethylation of lysine 9 (H3K9me3) and proteins of the heterochromatin protein 1 (HP1) family are hallmarks of heterochromatin, a state of compacted DNA essential for genome stability and long-term transcriptional silencing. The mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8eb3af37c1c77dbd9b956d1a8f4e9e5
https://doi.org/10.1038/ncomms11310
https://doi.org/10.1038/ncomms11310
Autor:
Nils Kost, Renate Renkawitz-Pohl, Miroslav Nikolov, Wolfgang Fischle, Christina Rathke, Dietmar Riedel, Alexandra Stützer, Sophie Kaiser, Yogesh B. Ostwal
Publikováno v:
Nucleic Acids Research
Despite insights on the cellular level, the molecular details of chromatin reorganization in sperm development, which involves replacement of histone proteins by specialized factors to allow ultra most condensation of the genome, are not well underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c559d47c6b01fb1e88b366f9b2a4883
https://hdl.handle.net/11858/00-001M-0000-0025-7418-811858/00-001M-0000-0025-741A-411858/00-001M-0000-0025-741B-2
https://hdl.handle.net/11858/00-001M-0000-0025-7418-811858/00-001M-0000-0025-741A-411858/00-001M-0000-0025-741B-2
Autor:
Peter Walla, Markus Zweckstetter, Stefan Becker, Nasrollah Rezaei-Ghaleh, Wolfgang Fischle, Francesca Munari, Nils Kost, Alexandra Stützer, Rebecca Klingberg, Dirk Schwarzer, Kathy Ann Gelato, Bastian Zimmermann, Hans Michael Zenn, Sabrina Schröder, Adrian Schomburg, Szabolcs Soeroes
Publikováno v:
The journal of biological chemistry 287(40), 33756-33765 (2012). doi:10.1074/jbc.M112.390849
The journal of biological chemistry, 287: 33756-33765
Journal of Biological Chemistry
The journal of biological chemistry, 287: 33756-33765
Journal of Biological Chemistry
CAPSULE: BACKGROUND: Chromatin-HP1 (heterochromatin protein 1) interaction is crucial for heterochromatin assembly. RESULTS: hHP1β uses alternative interfaces to bind nucleosomes depending on histone 3 methylation within a highly dynamic complex. CO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f67324e819c48c3733b935768b83f9
http://hdl.handle.net/11562/973712
http://hdl.handle.net/11562/973712
Autor:
Dinshaw J. Patel, Stephen D. Nimer, Nils Kost, Zuoheng Wang, Xiao-Jian Sun, Olivier Elemento, T. D. Soong, T. Nakadai, Wei Yi Chen, Yanwen Jiang, Zhanyun Tang, Wolfgang Fischle, R. G. Röder, Ari Melnick
Publikováno v:
Cancer Research. 73:LB-111
Transcription factors are frequently altered in leukemia through chromosomal translocation, mutation or aberrant expression. AML1-ETO, a fusion protein generated by the t(8;21) translocation in acute myeloid leukemia (AML), is a transcription factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca9a1a2db1bf1aa249fffdbc3e7dd808
https://doi.org/10.1158/1538-7445.am2013-lb-111
https://doi.org/10.1158/1538-7445.am2013-lb-111