Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nils Homer"'
Autor:
Michael James Clark, Nils Homer, Brian D O'Connor, Zugen Chen, Ascia Eskin, Hane Lee, Barry Merriman, Stanley F Nelson
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007392 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1000832.].
Externí odkaz:
https://doaj.org/article/73af865225ee49c598b02cb89e808d4d
Autor:
Michael James Clark, Nils Homer, Brian D O'Connor, Zugen Chen, Ascia Eskin, Hane Lee, Barry Merriman, Stanley F Nelson
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000832 (2010)
U87MG is a commonly studied grade IV glioma cell line that has been analyzed in at least 1,700 publications over four decades. In order to comprehensively characterize the genome of this cell line and to serve as a model of broad cancer genome sequen
Externí odkaz:
https://doaj.org/article/ef09ff9dfbbe4e8799a9b10e7a4d3823
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7767 (2009)
BACKGROUND:The new generation of massively parallel DNA sequencers, combined with the challenge of whole human genome resequencing, result in the need for rapid and accurate alignment of billions of short DNA sequence reads to a large reference genom
Externí odkaz:
https://doaj.org/article/020b391cc56844ae9e96162b43e3ba8e
Autor:
Nils Homer, Szabolcs Szelinger, Margot Redman, David Duggan, Waibhav Tembe, Jill Muehling, John V Pearson, Dietrich A Stephan, Stanley F Nelson, David W Craig
Publikováno v:
PLoS Genetics, Vol 4, Iss 8, p e1000167 (2008)
We use high-density single nucleotide polymorphism (SNP) genotyping microarrays to demonstrate the ability to accurately and robustly determine whether individuals are in a complex genomic DNA mixture. We first develop a theoretical framework for det
Externí odkaz:
https://doaj.org/article/c9895e435c9a4521b761c40ee612f8a4
Autor:
June Snedecor, Tim Fennell, Seth Stadick, Nils Homer, Joana Antunes, Kathryn Stephens, Cydne Holt
1.AbstractForensic genetic genealogy (FGG) has primarily relied upon dense single nucleotide polymorphism (SNP) profiles from forensic samples or unidentified human remains queried against online genealogy database(s) of known profiles generated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0839bddd7099995e130d678bec6eaa1b
https://doi.org/10.1101/2022.08.22.504804
https://doi.org/10.1101/2022.08.22.504804
Correction: U87MG Decoded: The Genomic Sequence of a Cytogenetically Aberrant Human Cancer Cell Line
Autor:
Zugen Chen, Ascia Eskin, Barry Merriman, Michael J. Clark, Brian O'Connor, Hane Lee, Stanley F. Nelson, Nils Homer
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 5, p e1007392 (2018)
PLoS Genetics, Vol 14, Iss 5, p e1007392 (2018)
U87MG is a commonly studied grade IV glioma cell line that has been analyzed in at least 1,700 publications over four decades. In order to comprehensively characterize the genome of this cell line and to serve as a model of broad cancer genome sequen
Autor:
Heng Li, Nils Homer
Publikováno v:
Briefings in Bioinformatics. 11:473-483
Rapidly evolving sequencing technologies produce data on an unparalleled scale. A central challenge to the analysis of this data is sequence alignment, whereby sequence reads must be compared to a reference. A wide variety of alignment algorithms and
Publikováno v:
Journal of Computational Biology. 16:565-577
As a first step in analyzing high-throughput data in genome-wide studies, several algorithms are available to identify and prioritize candidates lists for downstream fine-mapping. The prioritized candidates could be differentially expressed genes, ab
Autor:
Margot Redman, Nils Homer, Trisha Laub, Szabolcs Szelinger, Traci Pawlowski, Aswin Sekar, Gary Nunn, Matthew J. Huentelman, John V. Pearson, David Craig, Dietrich A. Stephan, Jason J. Corneveaux
Publikováno v:
Nature methods
We developed a generalized framework for multiplexed resequencing of targeted regions of the human genome on the Illumina Genome Analyzer using degenerate indexed DNA sequence barcodes ligated to fragmented DNA prior to sequencing. Using this method,
Autor:
John V. Pearson, Margot Redman, Nils Homer, Dietrich A. Stephan, Szabolcs Szelinger, David Craig, Waibhav Tembe, Stanley F. Nelson
Publikováno v:
Bioinformatics. 24:1896-1902
Summary: For many genome-wide association (GWA) studies individually genotyping one million or more SNPs provides a marginal increase in coverage at a substantial cost. Much of the information gained is redundant due to the correlation structure inhe