Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards

Autor: Federico Torta, Nils Hoffmann, Bo Burla, Irina Alecu, Makoto Arita, Takeshi Bamba, Steffany A. L. Bennett, Justine Bertrand-Michel, Britta Brügger, Mónica P. Cala, Dolores Camacho-Muñoz, Antonio Checa, Michael Chen, Michaela Chocholoušková, Michelle Cinel, Emeline Chu-Van, Benoit Colsch, Cristina Coman, Lisa Connell, Bebiana C. Sousa, Alex M. Dickens, Maria Fedorova, Finnur Freyr Eiríksson, Hector Gallart-Ayala, Mohan Ghorasaini, Martin Giera, Xue Li Guan, Mark Haid, Thomas Hankemeier, Amy Harms, Marcus Höring, Michal Holčapek, Thorsten Hornemann, Chunxiu Hu, Andreas J. Hülsmeier, Kevin Huynh, Christina M. Jones, Julijana Ivanisevic, Yoshihiro Izumi, Harald C. Köfeler, Sin Man Lam, Mike Lange, Jong Cheol Lee, Gerhard Liebisch, Katrice Lippa, Andrea F. Lopez-Clavijo, Malena Manzi, Manuela R. Martinefski, Raviswamy G. H. Math, Satyajit Mayor, Peter J. Meikle, María Eugenia Monge, Myeong Hee Moon, Sneha Muralidharan, Anna Nicolaou, Thao Nguyen-Tran, Valerie B. O’Donnell, Matej Orešič, Arvind Ramanathan, Fabien Riols, Daisuke Saigusa, Tracey B. Schock, Heidi Schwartz-Zimmermann, Guanghou Shui, Madhulika Singh, Masatomo Takahashi, Margrét Thorsteinsdóttir, Noriyuki Tomiyasu, Anthony Tournadre, Hiroshi Tsugawa, Victoria J. Tyrrell, Grace van der Gugten, Michael O. Wakelam, Craig E. Wheelock, Denise Wolrab, Guowang Xu, Tianrun Xu, John A. Bowden, Kim Ekroos, Robert Ahrends, Markus R. Wenk

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Abstract In this community effort, we compare measurements between 34 laboratories from 19 countries, utilizing mixtures of labelled authentic synthetic standards, to quantify by mass spectrometry four clinically used ceramide species in the NIST (Na

Externí odkaz: https://doaj.org/article/e8653562ef70466097f27cb7fad363e8

The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data

Autor: Dominik Kopczynski, Christer S. Ejsing, Jeffrey G. McDonald, Takeshi Bamba, Erin S. Baker, Justine Bertrand-Michel, Britta Brügger, Cristina Coman, Shane R. Ellis, Timothy J. Garrett, William J. Griffiths, Xue Li Guan, Xianlin Han, Marcus Höring, Michal Holčapek, Nils Hoffmann, Kevin Huynh, Rainer Lehmann, Jace W. Jones, Rima Kaddurah-Daouk, Harald C. Köfeler, Peter J. Meikle, Thomas O. Metz, Valerie B. O’Donnell, Daisuke Saigusa, Dominik Schwudke, Andrej Shevchenko, Federico Torta, Juan Antonio Vizcaíno, Ruth Welti, Markus R. Wenk, Denise Wolrab, Yu Xia, Kim Ekroos, Robert Ahrends, Gerhard Liebisch

Publikováno v: Journal of Lipid Research, Vol 65, Iss 9, Pp 100621- (2024)

The rapid increase in lipidomic studies has led to a collaborative effort within the community to establish standards and criteria for producing, documenting, and disseminating data. Creating a dynamic easy-to-use checklist that condenses key informa

Externí odkaz: https://doaj.org/article/3fdedc2e62704f2cb1a553af8d558f83

LipidCreator workbench to probe the lipidomic landscape

Autor: Bing Peng, Dominik Kopczynski, Brian S. Pratt, Christer S. Ejsing, Bo Burla, Martin Hermansson, Peter Imre Benke, Sock Hwee Tan, Mark Y. Chan, Federico Torta, Dominik Schwudke, Sven W. Meckelmann, Cristina Coman, Oliver J. Schmitz, Brendan MacLean, Mailin-Christin Manke, Oliver Borst, Markus R. Wenk, Nils Hoffmann, Robert Ahrends

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

Targeted mass spectrometry enables reproducible and accurate lipid quantification but dedicated software tools to develop targeted lipidomics assays are lacking. Here, the authors develop a targeted lipidomics workbench and lipid knowledgebase for th

Externí odkaz: https://doaj.org/article/cf125a979bd74b198ac9797a20846f29

Recommendations for good practice in MS-based lipidomics

Autor: Harald C. Köfeler, Robert Ahrends, Erin S. Baker, Kim Ekroos, Xianlin Han, Nils Hoffmann, Michal Holčapek, Markus R. Wenk, Gerhard Liebisch

Publikováno v: Journal of Lipid Research, Vol 62, Iss , Pp 100138- (2021)

In the last 2 decades, lipidomics has become one of the fastest expanding scientific disciplines in biomedical research. With an increasing number of new research groups to the field, it is even more important to design guidelines for assuring high s

Externí odkaz: https://doaj.org/article/92a585f7f3db439c898bcd07c0242453

The History of Carbohydrates in Type I Allergy

Autor: Miriam Hils, Florian Wölbing, Christiane Hilger, Jörg Fischer, Nils Hoffard, Tilo Biedermann

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Although first described decades ago, the relevance of carbohydrate specific antibodies as mediators of type I allergy had not been recognized until recently. Previously, allergen specific IgE antibodies binding to carbohydrate epitopes were consider

Externí odkaz: https://doaj.org/article/41f0652e2274413ebe06318778bf3dee