Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nils Dragsted"'
Autor:
Alan S. Bass, David Jones, Derek J. Leishman, Siddhartha Bhatt, Martin Traebert, Nils Dragsted, Jean-Pierre Valentin, Theodore J. Baird, Simon Authier, Ninette K. Andersen, Tomas Mow, Carrie Markgraf, Anders B. Lassen, Michael J. Curtis, Morten Laursen
Publikováno v:
Journal of pharmacological and toxicological methods. 105
In nonclinical toxicology the highest dose or exposure without test article-related adverse effects, known as the No Observed Adverse Effect Level (NOAEL), is a variable that may be determined. In safety pharmacology the vast majority of the endpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a22db161525d63f0329202b7e471ab
https://pubmed.ncbi.nlm.nih.gov/32866658
https://pubmed.ncbi.nlm.nih.gov/32866658
Autor:
Olivier Meyer, Ingrid Sjögren, Aileen Milne, Anders B. Lassen, Warren Harvey, Nils Dragsted, Rastislav Bator, Julie M. Larsen, Alys Bradley, Ninette K. Andersen
Publikováno v:
Journal of pharmacological and toxicological methods. 87
Introduction The novel PhysioTel™ Digital M11 telemetry implant was evaluated in socially housed monkeys with respect to both safety pharmacological cardiovascular (arterial blood pressure (BP), heart rate (HR) and electrocardiogram (ECG)) and toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb867fb6a999b4e7db30c1c3b778f490
https://pubmed.ncbi.nlm.nih.gov/28416413
https://pubmed.ncbi.nlm.nih.gov/28416413
Autor:
Michael J. Engwall, Simon Authier, Morten Laursen, Michael J. Curtis, Siddhartha Bhatt, Derek J. Leishman, Martin Traebert, Ninette K. Andersen, Alan S. Bass, David K. Jones, Tomas Mow, Carrie G. Markgraf, Theodore J. Baird, Nils Dragsted, Anders B. Lassen, Jean-Pierre Valentin, Zindy Raida
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 93:172-173
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c127f5f4fdd44eae1c35b57ae04cbec
https://doi.org/10.1016/j.vascn.2018.01.557
https://doi.org/10.1016/j.vascn.2018.01.557
Publikováno v:
Laboratory Animals. 37:94-99
The widespread use of individually ventilated cage (IVC) systems today has made the impact of CO2 on rodents a highly important matter. Leaving cages from these systems without ventilation increases CO2 concentrations inside the cages, as CO2 generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ac58ea38345571d0566b88b1e971cd
https://doi.org/10.1258/00236770360563723
https://doi.org/10.1258/00236770360563723
Publikováno v:
Laboratory Animals. 37:85-93
Today the use of individually ventilated cage systems (IVC systems) is common, especially for housing transgenic rodents. Typically, in each cage a ventilation rate of 40 to 50 air changes per hour is applied, but in some systems even up to 120 air c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc6965365c70e3b211936300a71b49e
https://doi.org/10.1258/00236770360563714
https://doi.org/10.1258/00236770360563714
Autor:
Lone Pridal, Finn Junager, Nils Dragsted, Anette Koch, J. Bondo Hansen, Svend Treppendahl, John Patrick Mogensen, Lars Ynddal, Anne Worsaae, Tina Møller Tagmose, Harrie C. M. Boonen, Per Arkhammar, Peter Mackay, Carsten Enggaard Stidsen, Philip Wahl, Thora B. Bodvarsdottir, Flemming Elmelund Nielsen
Publikováno v:
Journal of Medicinal Chemistry. 45:4171-4187
6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives were synthesized and characterized as activators of adenosine 5'-triphosphate (ATP) sensitive potassium (K(ATP)) channels in the beta-cells by measuring effects on membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad57c06500aa329c5150f5eecdc7560
https://doi.org/10.1021/jm0208121
https://doi.org/10.1021/jm0208121
Publikováno v:
European Journal of Pharmacology. 336:29-35
We have investigated the adrenergic antagonist effect of the antipsychotic sertindole in rat resistance vessels and in membranes of HEK293 cells transfected with alpha1-adrenoceptors. Segments of rat mesenteric small arteries or rat aorta were mounte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152df9e209e8971fe83bd7c6f7bac462
https://doi.org/10.1016/s0014-2999(97)01242-9
https://doi.org/10.1016/s0014-2999(97)01242-9
Publikováno v:
Laboratory animals. 40(3)
Rats with implanted telemetry transponders were blood sampled by jugular puncture, periorbital puncture or tail vein puncture, or sampled by jugular puncture in carbon dioxide (CO2), isoflurane or without anaesthesia in a crossover design. Heart rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea612ee87fb66bd770794c5a0598f73
https://pubmed.ncbi.nlm.nih.gov/16803643
https://pubmed.ncbi.nlm.nih.gov/16803643
Publikováno v:
Psychopharmacology. 137(3)
Lu 25-109 [5-(2-ethyl-2H-tetrazol-5-yl)-1,2, 3,6-tetrahydro-l-methylpyridine], has M1 agonistic and M2/M3 antagonistic effects at muscarinic receptors in vitro; a pharmacological profile that may be beneficial in treatment of Alzheimer’s disease. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d18da7f275a0327d700fe848d90387
https://pubmed.ncbi.nlm.nih.gov/9683000
https://pubmed.ncbi.nlm.nih.gov/9683000
Publikováno v:
Laboratory Animals; Apr2003, Vol. 37 Issue 2, p94, 6p