Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Nils C. Gauthier"'
Autor:
Andrea Ghisleni, Mayte Bonilla-Quintana, Michele Crestani, Zeno Lavagnino, Camilla Galli, Padmini Rangamani, Nils C. Gauthier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The cell cortex is a dynamic assembly formed by the plasma membrane and underlying cytoskeleton. As the main determinant of cell shape, the cortex ensures its integrity during passive and active deformations by adapting cytoskeleton topologi
Externí odkaz:
https://doaj.org/article/6ddace85f98342838f848ede09c0f3ef
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101331- (2022)
Summary: Glioblastoma (GBM) cells invade the brain by following linear structures like blood vessel walls and white matter tracts by using specific motility modes. In this protocol, we describe two micropatterning techniques allowing recapitulation o
Externí odkaz:
https://doaj.org/article/7448656c377c4c499400bd1550c90422
Autor:
Andrea Ghisleni, Camilla Galli, Pascale Monzo, Flora Ascione, Marc-Antoine Fardin, Giorgio Scita, Qingsen Li, Paolo Maiuri, Nils C. Gauthier
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
The cell cortex that supports the plasma membrane contains spectrin, a protein that interacts with the acto-myosin cytoskeleton. Here, the authors analyze spectrin behavior during cellular mechanoresponse and membrane trafficking, and observe spectri
Externí odkaz:
https://doaj.org/article/b49028cf2ff84964a7c443b6f61b4c67
Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis
Autor:
Sarah R. Barger, Nicholas S. Reilly, Maria S. Shutova, Qingsen Li, Paolo Maiuri, John M. Heddleston, Mark S. Mooseker, Richard A. Flavell, Tatyana Svitkina, Patrick W. Oakes, Mira Krendel, Nils C. Gauthier
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Phagocytosis of pathogens is thought to proceed through the sequential engagement of Fc-receptors on the phagocyte with antibodies on the target surface. Here authors show that myosin 1e and myosin 1f link the actin cytoskeleton to the membrane and a
Externí odkaz:
https://doaj.org/article/42adf260ea6c448fbdbf17cfb3eda9f6
Publikováno v:
Physical Review Research, Vol 2, Iss 3, p 033237 (2020)
During migration, cells exhibit a rich variety of seemingly random migration patterns, which makes unraveling the underlying mechanisms that control cell migration a difficult challenge. For efficient migration, cells require a mechanism for polariza
Externí odkaz:
https://doaj.org/article/289da6f9627e45a7b7820333808583bc
Autor:
Prabuddha Gupta, Nils C. Gauthier, Yu Cheng-Han, Yuan Zuanning, Bruno Pontes, Malte Ohmstede, René Martin, Hans-Joachim Knölker, Hans-Günther Döbereiner, Mira Krendel, Michael Sheetz
Publikováno v:
Biology Open, Vol 2, Iss 12, Pp 1288-1299 (2013)
Summary Because the actin network in active lamellipodia is continuously assembling at the edge, moving inward and disassembling, there is a question as to how actin-binding proteins and other components are transported to the leading edge and how na
Externí odkaz:
https://doaj.org/article/c4553e7e02cf4a579b58abc3b35031f5
Autor:
Daan Vorselen, Sarah R Barger, Yifan Wang, Wei Cai, Julie A Theriot, Nils C Gauthier, Mira Krendel
Publikováno v:
eLife, Vol 10 (2021)
Phagocytosis requires rapid actin reorganization and spatially controlled force generation to ingest targets ranging from pathogens to apoptotic cells. How actomyosin activity directs membrane extensions to engulf such diverse targets remains unclear
Externí odkaz:
https://doaj.org/article/aef0f4ad09434fbab2364d8bb7e93e64
Autor:
Raj Kumar Sadhu, Sarah R. Barger, Samo Penič, Aleš Iglič, Mira Krendel, Nils C. Gauthier, Nir S. Gov
Publikováno v:
Soft Matter. 19:31-43
Phagocytosis is the process of engulfment and internalization of comparatively large particles by cells, and plays a central role in the functioning of our immune system. We study the process of phagocytosis by considering a simplified coarse grained
Autor:
Michele Crestani, Nikolaos Kakogiannos, Fabio Iannelli, Tania Dini, Claudio Maderna, Monica Giannotta, Giuliana Pelicci, Paolo Maiuri, Pascale Monzo, Nils C. Gauthier
Glioblastomas are heterogeneous, primary brain tumors hiding several sub-populations. Patient-derived xenografts are considered gold-standards to study glioblastoma invasion. However, they present many disadvantages, including time consumption, compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a48ece0915a1d480c05681be5c2feaea
https://doi.org/10.1101/2023.02.24.529679
https://doi.org/10.1101/2023.02.24.529679