Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Nils B. Becker"'
Autor:
Mina N. F. Morcos, Congxin Li, Clara M. Munz, Alessandro Greco, Nicole Dressel, Susanne Reinhardt, Katrin Sameith, Andreas Dahl, Nils B. Becker, Axel Roers, Thomas Höfer, Alexander Gerbaulet
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Hematopoietic stem cells produce diverse cell lineages. Here, the authors apply single-cell RNA-seq, computational integration of non-perturbative approaches for fate-mapping, and mitotic tracking to chart lineage decisions in native hematopoiesis an
Externí odkaz:
https://doaj.org/article/6dc5319467ea4f6cb5ff6f5b2c8e6b18
Autor:
Vanessa S Stürmer, Sophie Stopper, Patrick Binder, Anja Klemmer, Nicolas P Lichti, Nils B Becker, Julien Guizetti
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011807 (2023)
Malaria is caused by the rapid proliferation of Plasmodium parasites in patients and disease severity correlates with the number of infected red blood cells in circulation. Parasite multiplication within red blood cells is called schizogony and occur
Externí odkaz:
https://doaj.org/article/57c3e9705a3d4c2db08ef00bed8ccc9c
Autor:
Stefanie Scherer, Susanne G. Oberle, Kristiyan Kanev, Ann-Katrin Gerullis, Ming Wu, Gustavo P. de Almeida, Daniel J. Puleston, Francesc Baixauli, Lilian Aly, Alessandro Greco, Tamar Nizharadze, Nils B. Becker, Madlaina v. Hoesslin, Lara V. Donhauser, Jacqueline Berner, Talyn Chu, Hayley A. McNamara, Zeynep Esencan, Patrick Roelli, Christine Wurmser, Ingo Kleiter, Maria J. G. T. Vehreschild, Christoph A. Mayer, Percy Knolle, Martin Klingenspor, Valeria Fumagalli, Matteo Iannacone, Martin Prlic, Thomas Korn, Erika L. Pearce, Thomas Höfer, Anna M. Schulz, Dietmar Zehn
Publikováno v:
Nature Immunology
Blocking pyrimidine de novo synthesis by inhibiting dihydroorotate dehydrogenase is used to treat autoimmunity and prevent expansion of rapidly dividing cell populations including activated T cells. Here we show memory T cell precursors are resistant
Publikováno v:
eLife, Vol 9 (2020)
Cell heterogeneity may be caused by stochastic or deterministic effects. The inheritance of regulators through cell division is a key deterministic force, but identifying inheritance effects in a systematic manner has been challenging. Here, we measu
Externí odkaz:
https://doaj.org/article/1209053ba7064e51b1cefe170e40feea
Autor:
Vanessa S. Stürmer, Sophie Stopper, Patrick Binder, Anja Klemmer, Nils B. Becker, Julien Guizetti
Malaria is caused by the rapid proliferation ofPlasmodiumparasites in patients and disease severity correlates with the number of infected red blood cells in circulation. Parasite multiplication within red blood cells is called schizogony and occurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6d445477de6dbab517fd07e9448523a
https://doi.org/10.1101/2023.01.20.524890
https://doi.org/10.1101/2023.01.20.524890
Autor:
Age J. Tjalma, Vahe Galstyan, Jeroen Goedhart, Lotte Slim, Nils B. Becker, Pieter Rein ten Wolde
Living cells can leverage correlations in environmental fluctuations to predict the future environment and mount a response ahead of time. To this end, cells need to encode the past signal into the output of the intracellular network from which the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f0084d9a7de15bd4db7c896189af9d
http://arxiv.org/abs/2301.03964
http://arxiv.org/abs/2301.03964
Autor:
Severina Klaus, Patrick Binder, Juyeop Kim, Marta Machado, Charlotta Funaya, Violetta Schaaf, Darius Klaschka, Aiste Kudulyte, Marek Cyrklaff, Vibor Laketa, Thomas Höfer, Julien Guizetti, Nils B. Becker, Friedrich Frischknecht, Ulrich S. Schwarz, Markus Ganter
Publikováno v:
Science Advances. 8
Malaria-causing parasites proliferate within erythrocytes through schizogony, forming multinucleated stages before cellularization. Nuclear multiplication does not follow a strict geometric 2 n progression, and each proliferative cycle produces a var
Publikováno v:
The ISME Journal
ISME J
ISME J
Quality–quantity tradeoffs govern the production of propagules across taxa and can explain variability in life-history traits in higher organisms. A quality–quantity tradeoff was recently discovered in spore forming bacteria, but whether it impac
Publikováno v:
Journal of Theoretical Biology. 481:100-109
Hematopoiesis is a paradigm for tissue development and renewal from stem cells. Experiments show that the maintenance of hematopoietic stem cells (HSCs) relies on signals from niche cells. However, it is not known how the size of the HSC compartment
Publikováno v:
Proc Natl Acad Sci U S A
In multicellular organisms, antiviral defense mechanisms evoke a reliable collective immune response despite the noisy nature of biochemical communication between tissue cells. A molecular hub of this response, the interferon I receptor (IFNAR), disc