Výsledky vyhledávání - "Nils A. Kulak"

Akademický článek

Proteomics Analysis of Monocyte-Derived Hepatocyte-Like Cells Identifies Integrin Beta 3 as a Specific Biomarker for Drug-Induced Liver Injury by Diclofenac

Autor: Diana Dragoi, Andreas Benesic, Garwin Pichler, Nils A. Kulak, Harald S. Bartsch, Alexander L. Gerbes

Publikováno v: Frontiers in Pharmacology, Vol 9 (2018)

Idiosyncratic drug-induced liver injury (iDILI) is a major cause of acute liver failure resulting in liver transplantation or death. Prediction and diagnosis of iDILI remain a great challenge, as current models provide unsatisfying results in terms o

Externí odkaz: https://doaj.org/article/2b6b684fe35942e89d4439aaa8b3ae41

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Loss-less Nano-fractionator for High Sensitivity, High Coverage Proteomics

Autor: Philipp E. Geyer, Nils A. Kulak, Matthias Mann

Publikováno v: Kulak, N A, Geyer, P E & Mann, M 2017, ' Loss-less Nano-fractionator for High Sensitivity, High Coverage Proteomics ', Molecular and Cellular Proteomics, vol. 16, no. 4, pp. 694-705 . https://doi.org/10.1074/mcp.O116.065136
Molecular & Cellular Proteomics : MCP
Molecular and Cellular Proteomics

Recent advances in mass spectrometry (MS)-based proteomics now allow very deep coverage of cellular proteomes. To achieve near-comprehensive identification and quantification, the combination of a first HPLC-based peptide fractionation orthogonal to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00100fd6e21338fa0ade85496dc5f69c
https://doi.org/10.1074/mcp.o116.065136

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Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans

Autor: Matthias Mann, Alexander Kohlmaier, Gabor Gäbel, Frank Beutner, Alexandros Nicolaou, Lesca M. Holdt, Bernd H. Northoff, Andreas Herbst, Anika Stahringer, Wolfgang Wilfert, Garwin Pichler, Markus Scholz, Daniel Teupser, Knut Krohn, Joachim Thiery, Nils A. Kulak, Kiran Musunuru, Kristina Sass

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications

Circular RNAs (circRNAs) are broadly expressed in eukaryotic cells, but their molecular mechanism in human disease remains obscure. Here we show that circular antisense non-coding RNA in the INK4 locus (circANRIL), which is transcribed at a locus of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5e947921932628f9792f1ea37324bf
https://doaj.org/article/151d6b7d2525435dacde77b53d5d85b1

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Proteomanalyse von hepatozyten-ähnlichen Zellen monozytären Ursprungs identifiziert ITGB3 als Biomarker für medikamentös-toxische Leberschäden durch Diclofenac

Autor: Andreas Benesic, Nils A. Kulak, D Dragoi, Alexander L. Gerbes, Harald Bartsch, Garwin Pichler

Publikováno v: Information und Programm: www.gfgb.org.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02c10f9689bed4ab4a5cf01f248f23f3
https://doi.org/10.1055/s-0038-1648566

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A Double-Barrel Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) System to Quantify 96 Interactomes per Day*

Autor: Eva C. Keilhauer, Fabian Hosp, Nils A. Kulak, Korbinian Mayr, Matthias Mann, H. Christian Eberl, Richard A. Scheltema

Publikováno v: Molecular & Cellular Proteomics : MCP
MOLECULAR & CELLULAR PROTEOMICS

The field of proteomics has evolved hand-in-hand with technological advances in LC-MS/MS systems, now enabling the analysis of very deep proteomes in a reasonable time. However, most applications do not deal with full cell or tissue proteomes but rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a044c1ed37f669eadd7fe27e7782bc5a
https://doi.org/10.1074/mcp.o115.049460

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