Zobrazeno 1 - 10 of 43 pro vyhledávání: '"Nils A. ‘t Hart"'
1
Akademický článek
Methylprednisolone Treatment in Brain Death-Induced Lung Inflammation–A Dose Comparative Study in Rats
Autor: Judith E. Van Zanden, Nils A. ’T Hart, Petra J. Ottens, Bo Liu, Rolando A. Rebolledo, Michiel E. Erasmus, Henri G. D. Leuvenink
Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)
Background: The process of brain death (BD) leads to a pro-inflammatory state of the donor lung, which deteriorates its quality. In an attempt to preserve lung quality, methylprednisolone is widely recommended in donor lung management. However, clini
Externí odkaz: https://doaj.org/article/1afef89b4ad54c299630b9dd7e5f6588
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2
Akademický článek
Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity
Autor: Daan van den Broek, T. Jeroen N. Hiltermann, Bonne Biesma, Winand N. M. Dinjens, Nils A. 't Hart, John W. J. Hinrichs, Mathie P. G. Leers, Kim Monkhorst, Matthijs van Oosterhout, Volkher Scharnhorst, Ed Schuuring, Ernst-Jan M. Speel, Michel M. van den Heuvel, Ron H. N. van Schaik, Jan von der Thüsen, Stefan M. Willems, Leonie de Visser, Marjolijn J. L. Ligtenberg
Publikováno v: Frontiers in Oncology, Vol 9 (2020)
The diagnostic landscape of non-small cell lung cancer (NSCLC) is changing rapidly with the availability of novel treatments. Despite high-level healthcare in the Netherlands, not all patients with NSCLC are tested with the currently relevant predict
Externí odkaz: https://doaj.org/article/690a5016a3c44acc879bb9a893ae5eb8
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3
Akademický článek
Hypothermic Oxygenated Machine Perfusion of the Human Donor Pancreas
Autor: Marjolein Leemkuil, MD, Grietje Lier, MD, Marten A. Engelse, PhD, Rutger J. Ploeg, PhD, Eelco J. P. de Koning, PhD, Nils A. ‘t Hart, PhD, Christina Krikke, MD, Henri G. D. Leuvenink, PhD
Publikováno v: Transplantation Direct, Vol 4, Iss 10, p e388 (2018)
Background. Transplantation of beta cells by pancreas or islet transplantation is the treatment of choice for a selected group of patients suffering from type 1 diabetes mellitus. Pancreata are frequently not accepted for transplantation, because of
Externí odkaz: https://doaj.org/article/e8cb835bdc2b41cb883976ee92e06ccd
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4
Akademický článek
Response to HER2 Inhibition in a Patient With Brain Metastasis With EGFR TKI Acquired Resistance and an HER2 Amplification
Autor: Arenda D. Meedendorp, Arja ter Elst, Nils A. ’t Hart, Harry J. M. Groen, Ed Schuuring, Anthonie J. van der Wekken
Publikováno v: Frontiers in Oncology, Vol 8 (2018)
A 62-year-old man was referred to our university hospital for treatment of advanced adenocarcinoma of the lung after disease progression on two lines of EGFR TKI and one line of chemotherapy. Fluorescent in situ hybridization analysis upon progressio
Externí odkaz: https://doaj.org/article/b480ae675d6142f99b0db7ea051f9a3c
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6
Quantitative comparison of PD-L1 IHC assays against NIST standard reference material 1934
Autor: Steven A. Bogen, Kodela Vani, Nils A 't Hart, Emina Torlakovic, Seshi R. Sompuram
Publikováno v: Modern Pathology. 35:326-332
Companion diagnostic immunohistochemistry (IHC) tests are developed and performed without incorporating the tools and principles of laboratory metrology. Basic analytic assay parameters such as lower limit of detection (LOD) and dynamic range are unk
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a984323d57fbfa341a06684caa815920
https://doi.org/10.1038/s41379-021-00884-w
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7
Formalin fixation for optimal concordance of programmed death-ligand 1 immunostaining between cytologic and histologic specimens from patients with non–small cell lung cancer
Autor: Bregje M Koomen, Nils A. 't Hart, Wim Timens, Stefan M. Willems, Judith M. Vonk, Jose van der Starre-Gaal, Kim Monkhorst, Jacqueline J C van der Meij, Jan H. von der Thüsen
Publikováno v: Cancer Cytopathology
Cancer cytopathology, 129(4), 304-317. Wiley
Cancer cytopathology, 129(4), 304-317. Wiley-Blackwell
Background Immunohistochemical staining of programmed death‐ligand 1 (PD‐L1) is used to determine which patients with non–small cell lung cancer (NSCLC) may benefit most from immunotherapy. Therapeutic management of many patients with NSCLC is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d52ac6a19a17afc0ce0209199c6617c
https://pure.eur.nl/en/publications/e93587c4-9710-4365-ba77-801c8bc23f84
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8
Staining Performance of ALK and ROS1 Immunohistochemistry and Influence on Interpretation in Non–Small-Cell Lung Cancer
Autor: Erik Thunnissen, Cleo Keppens, Karen Zwaenepoel, Elisabeth Dequeker, Ales Ryska, Jan H. von der Thüsen, Ed Schuuring, Nils A. 't Hart, Patrick Pauwels, Keith Miller
Publikováno v: Journal of Molecular Diagnostics, 22(12), 1438-1452. Elsevier Inc.
Journal of molecular diagnostics, 22(12), 1438-1452. ELSEVIER SCIENCE INC
The journal of molecular diagnostics
Keppens, C, von der Thüsen, J, Pauwels, P, Ryska, A, ’t Hart, N, Schuuring, E, Miller, K, Thunnissen, E, Zwaenepoel, K & Dequeker, E M C 2020, ' Staining Performance of ALK and ROS1 Immunohistochemistry and Influence on Interpretation in Non–Small-Cell Lung Cancer ', The Journal of molecular diagnostics, vol. 22, no. 12, pp. 1438-1452 . https://doi.org/10.1016/j.jmoldx.2020.09.006
The Journal of molecular diagnostics, 22(12), 1438-1452. Association of Molecular Pathology
Selection of non-small-cell lung cancer patients for treatment relies on the detection of expression of anaplastic lymphoma kinase (ALK) and ROS proto-oncogene 1 (ROS1) protein by immunohistochemistry (IHC). We evaluated staining performance for diff
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc4387d1f6871bb26bfb579e45f7902
https://doi.org/10.1016/j.jmoldx.2020.09.006
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9
The impact of a pathologist's personality on the interobserver variability and diagnostic accuracy of predictive PD-L1 immunohistochemistry in lung cancer
Autor: Rogier Butter, Liesbeth M. Hondelink, Lisette van Elswijk, Johannes L.G. Blaauwgeers, Elisabeth Bloemena, Rieneke Britstra, Nicole Bulkmans, Anna Lena van Gulik, Kim Monkhorst, Mathilda J. de Rooij, Ivana Slavujevic-Letic, Vincent T.H.B.M. Smit, Ernst-Jan M. Speel, Erik Thunnissen, Jan H. von der Thüsen, Wim Timens, Marc J. van de Vijver, David C.Y. Yick, Aeilko H. Zwinderman, Danielle Cohen, Nils A. 't Hart, Teodora Radonic
Publikováno v: Butter, R, Hondelink, L M, van Elswijk, L, Blaauwgeers, J L G, Bloemena, E, Britstra, R, Bulkmans, N, van Gulik, A L, Monkhorst, K, de Rooij, M J, Slavujevic-Letic, I, Smit, V T H B M, Speel, E-J M, Thunnissen, E, von der Thusen, J H, Timens, W, van de Vijver, M J, Yick, D C Y, Zwinderman, A H, Cohen, D, 't Hart, N A & Radonic, T 2022, ' The impact of a pathologist's personality on the interobserver variability and diagnostic accuracy of predictive PD-L1 immunohistochemistry in lung cancer ', Lung Cancer, vol. 166, pp. 143-149 . https://doi.org/10.1016/j.lungcan.2022.03.002
Lung Cancer, 166, 143-149. ELSEVIER IRELAND LTD
Lung Cancer, 166, 143-149. Elsevier Ireland Ltd
Lung cancer (Amsterdam, Netherlands), 166, 143-149. Elsevier Ireland Ltd
OBJECTIVES: Programmed death-ligand 1 (PD-L1) is the only approved predictive biomarker for immunotherapy in non-small cell lung cancer (NSCLC). However, predictive PD-L1 immunohistochemistry is subject to interobserver variability. We hypothesized t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e91c4dfdf95aaf2d5c8858a92d701a4
https://research.vumc.nl/en/publications/b0a56853-9990-4cd8-bc42-214dd162e9ce
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