Bidirectional crosstalk between Hypoxia-Inducible Factor and glucocorticoid signalling in zebrafish larvae.

Autor: Davide Marchi, Kirankumar Santhakumar, Eleanor Markham, Nan Li, Karl-Heinz Storbeck, Nils Krone, Vincent T Cunliffe, Fredericus J M van Eeden

Publikováno v: PLoS Genetics, Vol 16, Iss 5, p e1008757 (2020)

In the last decades in vitro studies highlighted the potential for crosstalk between Hypoxia-Inducible Factor-(HIF) and glucocorticoid-(GC) signalling pathways. However, how this interplay precisely occurs in vivo is still debated. Here, we use zebra

Externí odkaz: https://doaj.org/article/4120931580a945a6be7c6327869b7d77

Factors Associated With Response to Growth Hormone in Pediatric Growth Disorders: Results of a 5-year Registry Analysis

Autor: Judith Ross, Moshe Fridman, Nicky Kelepouris, Kristine Murray, Nils Krone, Michel Polak, Tilman R Rohrer, Alberto Pietropoli, Neil Lawrence, Philippe Backeljauw

Publikováno v: Journal of the Endocrine Society. 7

Context Growth hormone (GH) therapy can increase linear growth in patients with growth hormone deficiency (GHD), Turner syndrome (TS), Noonan syndrome (NS), and Prader-Willi syndrome (PWS), although outcomes vary by disease state. Objective To assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::289a3dc47fa0ed95bab595b26306e86c
https://doi.org/10.1210/jendso/bvad026

Gonadectomy in conditions affecting sex development

Autor: Daniel Konrad, Aneta Gawlik, Rajni Sharma, Olcay Evliyaoğlu, Dejun Li, Marek Niedziela, Jeremy W. Tomlinson, Farida Jennane, Nils Krone, Sukran Poyrazoglu, Evgenia Globa, S Faisal Ahmed, Angela K Lucas-Herald, Inas Mazen, Liat de Vries, Andreas Kyriakou, Katherine Lachlan, Wiebke Arlt, Renata Markosyan, Antonia Brooke, Olaf Hiort, Gil Guerra Júnior, Ruth Krone, Colin Johnston, Gloria Hermann, Antonio Balsamo, Corina Lichiardopol, Hedi L Claahsen-van der Grinten, Vandana Jain, Vilhelm Mladenov, Nataliya Zelinska, Naomi Weintrob, Markus Bettendorf, Simone Fica, Ieuan A. Hughes, Laura Audí, Lidka Lisa, Klaus Mohnike, Mona Ellaithi, Paul-Martin Holterhus, Lavinia Nedelea, Mars Skaeil, Rodolfo Rey, Violeta Iotova, Hannema Se, Silvano Bertelloni, Rieko Tadokoro-Cuccaro, Feyza Darendeliler, Jillian Bryce, Lloyd J.W. Tack, Tulay Guran, Odile Gaisl, Justin H Davies, Martine Cools, Anna Nordenström, Federico Baronio, Marie Lindhardt Ljubicic, Ayla Güven

Publikováno v: European Journal of Endocrinology, 184, 6, pp. 791-801
Lucas-Herald, A K, Bryce, J, Kyriakou, A, Ljubicic, M L, Arlt, W, Audí, L, Balsamo, A, Baronio, F, Bertelloni, S, Bettendorf, M, Brooke, A, Claahsen-van der Grinten, H L, Davies, J, Hermann, G, de Vries, L, Hughes, I A, Tadokoro-Cuccaro, R, Darendeliler, F, Poyrazoglu, S, Ellaithi, M, Evliyaoglu, O, Fica, S, Stejereanu, L, Gawlik, A, Globa, E, Zelinska, N, Guran, T, Güven, A, Hannema, S, Hiort, O, Holterhus, P-M, Iotova, V, Mladenov, V, Jain, V, Sharma, R, Jennane, F, Johnston, C, Guerra-Junior, G, Konrad, D, Gaisl, O, Krone, N P, Krone, R, Lachlan, K, Li, D, Lichiardopol, C, Lisá, L, Markosyan, R L, Mazen, I, Mohnike, K, Niedziela, M, Nordenstrom, A, Rey, R A, Skae, M, Tack, L J, Tomlinson, J W, Weintrob, N, Cools, M & Ahmed, S F 2021, ' Gonadectomy In Conditions Affecting Sex Development-A Registry-Based Cohort Study ', European Journal of Endocrinology, vol. 184, no. 6, pp. 791-801 . https://doi.org/10.1530/EJE-20-1058
European Journal of Endocrinology, 184, 791-801
European Journal of Endocrinology, 184(6), 791-801. BioScientifica Ltd.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
European Journal of Endocrinology, 184(6), 791-801. Bioscientifica Ltd

Objectives To determine trends in clinical practice for individuals with DSD requiring gonadectomy. Design Retrospective cohort study. Methods Information regarding age at gonadectomy according to diagnosis; reported sex; time of presentation to spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5736d4ded04c320636341b53c9ff773c
https://pure.eur.nl/en/publications/3d58e4e1-4750-4f4b-a9f2-3b057e09a236

International practice of corticosteroid replacement therapy in congenital adrenal hyperplasia

Autor: S. F. Ahmed, Tatjana Milenkovic, Eduardo Corrêa Costa, Ruth Krone, Berenice B Mendonca, Niels H Birkebaek, Tania A. S. S. Bachega, Andrea Luczay, Irina-Alexandra Bacila, Martijn J J Finken, Sukran Poyrazoglu, Z. Yavas Abalı, Feyza Darendeliler, Tulay Guran, Eleni Daniel, H. J. van der Kamp, Márta Korbonits, Ajay Thankamony, Ana Vieites, Oliver Blankenstein, Heba Elsedfy, Antonio Balsamo, M. Sandrk, Nils Krone, N. Freeman, Jeremy W. Tomlinson, Klaus Mohnike, Corina Lichiardopol, H.L. Claahsen-van der Grinten, Martine Cools, Walter Bonfig, Salma R Ali, Mirela C Miranda, Rita Ortolano, L. de Vries, Navoda Atapattu, Sabine E. Hannema, Silvia Einaudi, Evelien F. Gevers, J. Bryce, Claire E Higham, Ayla Guven, Richard J. Ross, Violeta Iotova, Uta Neumann

Publikováno v: European Journal of Endocrinology, 184, 553-563
European Journal of Endocrinology, 184(4), 553-563. BioScientifica Ltd.
Bacila, I, Freeman, N, Daniel, E, Sandrk, M, Bryce, J, Ali, S R, Abali, Z Y, Atapattu, N, Bachega, T A, Balsamo, A, Birkebæk, N, Blankenstein, O, Bonfig, W, Cools, M, Costa, E C, Darendeliler, F, Einaudi, S, Elsedfy, H H, Finken, M J J, Gevers, E, Claahsen-Van der Grinten, H L, Guran, T, Güven, A, Hannema, S E, Higham, C E, Iotova, V, van der Kamp, H J, Korbonits, M, Krone, R E, Lichiardopol, C, Luczay, A, Mendonca, B B, Milenkovic, T, Miranda, M C, Mohnike, K, Neumann, U, Ortolano, R, Poyrazoglu, S, Thankamony, A, Tomlinson, J W, Vieites, A, de Vries, L, Ahmed, S F, Ross, R J & Krone, N P 2021, ' International practice of corticosteroid replacement therapy in congenital adrenal hyperplasia : Data from the I-CAH registry ', European Journal of Endocrinology, vol. 184, no. 4, pp. 553-563 . https://doi.org/10.1530/EJE-20-1249
EUROPEAN JOURNAL OF ENDOCRINOLOGY
European Journal of Endocrinology, 184(4), 553-563. Bioscientifica Ltd
Bacila, I, Freeman, N, Daniel, E, Sandrk, M, Bryce, J, Ali, S R, Abali, Z Y, Atapattu, N, Bachega, T A, Balsamo, A, Birkebæk, N, Blankenstein, O, Bonfig, W, Cools, M, Costa, E C, Darendeliler, F, Einaudi, S, Elsedfy, H H, Finken, M J J, Gevers, E, Claahsen-van der Grinten, H L, Guran, T, Güven, A, Hannema, S E, Higham, C E, Iotova, V, van der Kamp, H J, Korbonits, M, Krone, R E, Lichiardopol, C, Luczay, A, Mendonca, B B, Milenkovic, T, Miranda, M C, Mohnike, K, Neumann, U, Ortolano, R, Poyrazoglu, S, Thankamony, A, Tomlinson, J W, Vieites, A, de Vries, L, Ahmed, S F, Ross, R J & Krone, N P 2021, ' International practice of corticosteroid replacement therapy in congenital adrenal hyperplasia : Data from the I-CAH registry ', European Journal of Endocrinology, vol. 184, no. 4, pp. 553-563 . https://doi.org/10.1530/EJE-20-1249
European Journal of Endocrinology, 184, 4, pp. 553-563

Objective Despite published guidelines no unified approach to hormone replacement in congenital adrenal hyperplasia (CAH) exists. We aimed to explore geographical and temporal variations in the treatment with glucocorticoids and mineralocorticoids in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f9154fc2019becbacb0d0946a9859f2
https://doi.org/10.1530/EJE-20-1249

Real-World Estimates of Adrenal Insufficiency-Related Adverse Events in Children With Congenital Adrenal Hyperplasia

Autor: Berenice B. Mendonca, Ana Vieites, Salma R Ali, Nils Krone, Martijn J J Finken, S Faisal Ahmed, Ayla Guven, Richard J. Ross, Silvia Einaudi, Violeta Iotova, Tulay Guran, Rieko Tadokoro-Cuccaro, Evelien F. Gevers, Guilherme Guaragna-Filho, Eduardo Corrêa Costa, James Lewsey, Hannema Se, Mirela C Miranda, Ruth Krone, Rita Ortolano, Niels H Birkebaek, Houra Haghpanahan, Tania A. S. S. Bachega, Andrea Luczay, Sukran Poyrazoglu, Jillian Bryce, Corina Lichiardopol, Christa E. Flück, Oliver Blankenstein, Antonio Balsamo, Ieuan A. Hughes, Claire E Higham, Liat de Vries, Feyza Darendeliler, Hedi L Claahsen-van der Grinten, Martine Cools, Hetty J. van der Kamp, Ajay Thankamony, Anna Nordenström, Navoda Atapattu, Klaus Mohnike, Heba Elsedfy, Walter Bonfig, Li En Tan, Uta Neumann, Márta Korbonits, Tatjana Milenkovic

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 106, 1, pp. E192-E203
The Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 106, E192-E203
Ali, S R, Bryce, J, Haghpanahan, H, Lewsey, J D, Tan, L E, Atapattu, N, Birkebaek, N H, Blankenstein, O, Neumann, U, Balsamo, A, Ortolano, R, Bonfig, W, Claahsen-Van Der Grinten, H L, Cools, M, Costa, E C, Darendeliler, F, Poyrazoglu, S, Elsedfy, H, Finken, M J J, Fluck, C E, Gevers, E, Korbonits, M, Guaragna-Filho, G, Guran, T, Guven, A, Hannema, S E, Higham, C, Hughes, I A, Tadokoro-Cuccaro, R, Thankamony, A, Iotova, V, Krone, N P, Krone, R, Lichiardopol, C, Luczay, A, Mendonca, B B, Bachega, T A S S, Miranda, M C, Milenkovic, T, Mohnike, K, Nordenstrom, A, Einaudi, S, Van Der Kamp, H, Vieites, A, De Vries, L, Ross, R J M & Ahmed, S F 2021, ' Real-World Estimates of Adrenal Insufficiency-Related Adverse Events in Children with Congenital Adrenal Hyperplasia ', Journal of Clinical Endocrinology and Metabolism, vol. 106, no. 1, pp. E192-E203 . https://doi.org/10.1210/clinem/dgaa694
Ali, S R, Bryce, J, Haghpanahan, H, Lewsey, J D, Tan, L E, Atapattu, N, Birkebaek, N H, Blankenstein, O, Neumann, U, Balsamo, A, Ortolano, R, Bonfig, W, Claahsen-van der Grinten, H L, Cools, M, Costa, E C, Darendeliler, F, Poyrazoglu, S, Elsedfy, H, Finken, M J J, Fluck, C E, Gevers, E, Korbonits, M, Guaragna-Filho, G, Guran, T, Guven, A, Hannema, S E, Higham, C, Hughes, I A, Tadokoro-Cuccaro, R, Thankamony, A, Iotova, V, Krone, N P, Krone, R, Lichiardopol, C, Luczay, A, Mendonca, B B, Bachega, T A S S, Miranda, M C, Milenkovic, T, Mohnike, K, Nordenstrom, A, Einaudi, S, van der Kamp, H, Vieites, A, de Vries, L, Ross, R J M & Ahmed, S F 2021, ' Real-World Estimates of Adrenal Insufficiency-Related Adverse Events in Children With Congenital Adrenal Hyperplasia ', The Journal of clinical endocrinology and metabolism, vol. 106, no. 1, pp. e192-e203 . https://doi.org/10.1210/clinem/dgaa694
The Journal of clinical endocrinology and metabolism, 106(1), e192-e203. Endocrine Society
The Journal of clinical endocrinology and metabolism, 106(1), e192-e203. The Endocrine Society

Background Although congenital adrenal hyperplasia (CAH) is known to be associated with adrenal crises (AC), its association with patient- or clinician-reported sick day episodes (SDE) is less clear. Methods Data on children with classic 21-hydroxyla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8842585b2800121bbcc719a1f184139c
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/230378